SelectScience InterviewsLife Sciences

Generate Images of Gels and Blots

2 May 2012
Generate Images of  Gels and Blots

Learn more about the new innovatively designed compact PXi for fast imaging of even the faintest bands in this video. Paul Ellwood, Syngene, explains the simplicity of using Syngene’s intuitive GeneSys imaging software and demonstrates how, with just one-click, scientists can generate perfect images of chemiluminescent blots, as well 1-D gels (up to 10cm x 12cm) stained with any fluorescence and IR commercial dyes time after time. Interview filmed by SelectScience at analytica 2012.

About the company

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Syngene

Headquartered in Cambridge, UK, and with a subsidiary operation in Frederick, Maryland, Syngene is a world leader in gel documentation (gel doc) and analysis systems, ranging from low cost entry level kits to fully computer controlled automatic analysers for fluorescence, chemiluminescence and proteomics workstations.

  • Gel documentation (gel doc) and image analysis systems for DNA and protein gels.
  • Chemiluminescence and fluorescence systems for Western blots and probes.
  • Proteomics hardware and software for 2D gel electrophoresis (2DGE).


    Syngene systems are used by more than 10,000 research organisations and over 50,000 individual scientists world-wide. Customers include many of the world?? top pharmaceutical companies and major research institutes. In addition to systems and software solutions, Syngene also provides technical expertise and extensive service support for its products.

    Syngene, founded in 1997 is a division of the Synoptics group. The other divisions, Syncroscopy and Synbiosis, specialise in digital imaging solutions for microscopy and microbial applications respectively. The Group uses sophisticated distribution channels to market its products with a global network of over 70 dealers and OEM partners.
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GeneSys

Syngene

The biggest difference between a Syngene system and any other is in the way the system is controlled. At the heart of all Syngene systems is GeneSys which is an application driven control software. You can use GeneSys in either Automatic or Manual mode. It is assumed that the user will know exactly what their application is and how they have prepared their gel or blot. In Auto Mode they simply enter this information into GeneSys (or recall it from a saved configuration) and the system takes over the rest. Behind GeneSys is an extensive database which contains data relating to a very wide range of applications, eg, fluorescence, chemiluminescene and chemifluorescence.Once the imaging system has been told what sample to expect then GeneSys decides what hardware configuration is best and sets the system ready for image capture. Things like camera control, exposure time, sensitivity setting, lighting requirements, lens control, filter selection – all of this is taken care of by GeneSys. The user just has to click the ‘capture’ button and wait for the perfect image to appear. GeneSys ensures scientists can quickly capture excellent images of even complex multiplex gels.The innovative GeneSys software features large touch-screen buttons which guide users effortlessly through set-up and image capture. Each screen prompts researchers to select, for example, the type of gel or blot they are using and what it is stained with.

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