ResourceDrug Discovery & Development
Researchers’ guide to products for ADME-Tox testing
5 Oct 2026This application note provides a comprehensive overview of BioIVT’s portfolio of in vitro ADME-Tox research products used to evaluate drug absorption, distribution, metabolism, excretion, and toxicity. Learn about primary hepatocytes, Kupffer cells, multicellular liver models, subcellular fractions and recombinant enzyme systems designed to support metabolism, drug-drug interaction, transporter, and toxicology studies. Plus, explore guidance on, species comparisons, product characterization, how to select appropriate test systems, and best practices for generating reliable, reproducible data throughout preclinical drug development.
Resource details:
Resource type: Application note
Page count: 29
Read time: 20 mins
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Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ADME
