Master EAD fragmentation for comprehensive characterization of next-gen protein therapeutics

6 Mar 2025

Find out how a groundbreaking electron-activated dissociation (EAD) approach can deliver deeper insights into complex therapeutics, including enhanced isomer identification, glycosylation profiling, and post-translational modification (PTM) analysis.

This SelectScience guide covers:

  • How EAD is a step change in fragmentation technology
  • Enhanced peptide mapping with collision-induced dissociation (CID) & EAD
  • Streamlined single-injection middle-down workflow
  • High sequence coverage & confident PTM analysis
  • Characterization of O-linked glycosylation
  • Enhanced sequence variant analysis

Discover advanced techniques in protein therapeutic development to optimize outcomes and overcome key challenges by downloading your free copy today.

Resource details:

  • Document type: SelectScience guide
  • Page count: 60
  • Read time: 90 mins
  • Edition: 1st

ZenoTOF 7600 system

SCIEX

Be extraordinary - welcome to the Zeno revolution, driven by the combined power of the Zeno trap and EAD

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Biologics Explorer software

SCIEX

Achieve clarity on your biotherapeutic. Leveraging the latest acquisition techniques and built on a heritage of proven performance, Biologics Explorer software delivers highly accurate and informative workflows for fully characterizing protein biotherapeutics. Reach decisions on the most important critical quality attributes for biopharmaceuticals faster and more confidently.

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EAD fragmentation for characterization of next-gen protein therapies - SelectScience guide