ResourceSeparations
Discover the Kinetex PS C18 HPLC/UHPLC Column’s Resistance to Dewetting and 100 % Aqueous Stability
18 Jul 2019This application note outlines a procedure for investigating potential retention time variation under high aqueous (> 99 % water) mobile phases conditions. The procedure involves stopping and restarting flow rate cycles and monitoring the retention of two polar basic probes (Dopamine and Epinephrine).
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Kinetex 2.6 µm PS C18
Phenomenex IncThe new Kinetex 2.6 µm PS C18 phase is beneficial for all types of compounds (acids, bases, neutrals), but especially for the analysis of polar basic compounds. The phase has demonstrated increased polar analyte retention, improved peak shape for troublesome basic analytes under typical reversed phase conditions, and a unique multi-modal interaction selectivity making it indispensable tool for multi-compound and metabolite profile screens.