Discover the Kinetex PS C18 HPLC/UHPLC Column’s Resistance to Dewetting and 100 % Aqueous Stability

This application note outlines a procedure for investigating potential retention time variation under high aqueous (> 99 % water) mobile phases conditions. The procedure involves stopping and restarting flow rate cycles and monitoring the retention of two polar basic probes (Dopamine and Epinephrine).