Next Generation Sequencing Products & Reviews

The Twist Alliance Clinical Research Exome helps support the Broad Institute Genomics Platform and was designed using validated data from clinical patient samples.

The Twist Alliance Canine Exome developed in collaboration with the Broad Institute

The Twist Alliance CNTG Exome - 41 MB provides highly uniform coverage of the entire exome as well as full coverage of the mitochondrial genome.

Coverage of rare disease-associated genes 

Coverage of 72 selected cancer-associated genes

The Twist Respiratory Virus Research Panel enables comprehensive detection and sequencing of 29 common respiratory viruses, allowing researchers to identify pathogens and analyze their genomes.

Fast and Easy Library Workflows

Twist's RNA Sequencing Solutions provide comprehensive next-generation sequencing (NGS) workflows, offering both targeted and whole transcriptome approaches to generate uniform, high-quality RNA sequencing libraries from diverse sample types.

The Twist RNA Exome offers a comprehensive solution for capturing human protein-coding regions, enabling efficient transcriptome analysis, isoform study, and fusion detection with high sensitivity and specificity.

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter System enhances the detection of low-frequency somatic variants in cell-free DNA (cfDNA) by incorporating unique molecular identifiers (UMIs) during library preparation, increasing sensitivity and reducing PCR errors.

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

BisCap® Human CpG Island Panel is targeted for detection of methylation status of 27,000 CpG island and also covers 13 commercial methylation markers. The panel could be widely used in methylation marker screening, early tumor screening, early detection, and etc.

Based on tumor-informed assays, combined with independently developed hybridization capture systems and high-throughput MRD Panel synthesis, we have launched a comprehensive MRD hybridization capture reagent set—including hybridization capture reagents, blocking sequences, and capture beads. Paired with free customized MRD Panels, this solution delivers a cost-effective and highly stable MRD detection protocol, promoting the p…

TargetSeq® Universal Blocking Oligo series products are used to block self-ligation of adapters to reduce non-specific adapter interaction during probe hybridization and thus to increase data utilization. iGeneTech offers 2 versions of universal blocking oligo for different library input in hybridization workflow, i.e., TargetSeq® Universal Blocking Oligo and TargetSeq® Eco Universal Blocking Oligo for up to 6 μg and 3 μg libr…

IGT® Adapter & UDI Primers is a series of adapter & unique dual-indexed primer kits used for NGS library construction of dsDNA, ssDNA and methylation DNA. iGeneTech provides 384 combinations of different UDI primers for high-throughput sequencing in a single lane, which reduces the false-positive rate caused by the index contaminations due to index hopping. For MultipSeq® library construction and low-frequency mutation tests,…

iGeneTech® owns the independently developed TargetSeq® hybridization capture sequencing technology and IGT® Oligo Pools synthesis platform, which enable the design of products targeting exon regions and offering comprehensive solutions for whole-exome sequencing across various species. As of now, we have successfully developed panels for the whole exomes of mice, rats, dogs, pigs, cattle, sheep, chickens, and more all of which…

TargetSeq® Human HLA Panel and TargetSeq® Human MHC Panel are HLA gene detection products based on TargetSeq® hybridization capture technology developed by iGeneTech. These panels are highly efficient in capturing the polymorphic region and combined with NGS technology to achieve high-precision typing of the HLA gene at 6 sites, and can be widely used in the field of immunology research.

IGT® Enzyme Plus Library Prep Kit V3 provides you a fast and streamlined workflow for NGS library preparation with enzymatic fragmentation strategy. The kit enables tunable fragmentation for different insert sizes according to experimental requirements and is suitable for genomic DNA and FFPE DNA samples with ranged sample input to generate satisfied yield. To achieve good performance with increased sequencing efficiency, IGT®…

TargetSeq One® Hyb & Wash Kit v3.0 is a fully upgraded version of the TargetSeq One® Hyb & Wash Kit. This upgrade has greatly simplified the reagent composition and operation process, reducing the operation time by more than 1 hour; meanwhile, in terms of product performance, the uniformity and capture efficiency have been significantly improved to a brand-new level. This means that the test results are accurate and reliable,…

AIExome® Human Exome Panel V5 is designed based on human reference genome GRCh38 and GRC. It covers about 34.69 Mb CDS region, and the probe coverage size is only 48.17 Mb, ensuring maximum coverage of the protein-coding region. AIExome® V5 has also been optimized for probe coverage of reference genome patches, high repeat regions and high GC content regions. AIExome® V5 series has 3 different versions and are open to semi-cus…

Clean up and size selection of DNA and RNA for NGS workflows using magnetic beads

Removal of unincorporated terminators from sequencing reactions using magnetic beads

In-depth understanding of complete genome in human, aninal, plant and microbe with end-to-end services.