ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…
Camargo ensures the appropriate regulatory requirements are met every step of the way, streamlining your drug development process all the way to approval.Ready to guide you through the preclinical stage of drug development, Camargo provides strategic support in the following areas: CRO selection Study design Study setup and execution Project management In clinical program development, camargo's focus is unwavering:…
Hepregen offers a range of DMPK services using their HepatoPac™ co-culture system. Hepregen has experienced scientific staff which work closely with our clients to design assays that meet their needs. We take great pride in our quality results and impeccable customer care. If you don't see your application of interest, our scientists can work with you to create a custom assay.DMPK Services: Metabolite Identification Intr…
Hepregen offers a range of toxicology services using their HepatoPac™ co-culture or Kupffer Cell Model systems. Hepregen's experienced scientific staff work closely with clients to design assays to meet their needs. Hepregen take great pride in their quality results and impeccable customer care. If you don't see your application of interest, their scientists can work with you to create a custom assay.Toxicology Services:…
Assessment of Neuronal Activity Using Microelectrode Array. The eCiphrNeuro assay uses primary cultures of rat cortical neurons. Cyprotex’s neuronal assay uses high throughput microelectrode array (MEA) technology to monitor electrophysiological activity. Neurons grown on microelectrode arrays recapitulate many features of neurons in vivo, including spontaneous activity (spiking and bursting), plasticity, organisation a…
At Peakdale we offer a range of in vitro ADMET predictive models, delivering accurate and reproducible data, maintaining a focus on efficient turnaround times to facilitate our customers' drug discovery programs. In addition to our core assays, we also offer our clients the flexibility of bespoke assay design. The majority of our assays utilise sensitive "state of the art" triple quad LC-MS/MS ESI detection. Complementing our…
Detect caspase-1 activity with the FLICA® Caspase 1 Assay Kit. This in vitro assay employs the green fluorescent inhibitor probe FAM-YVAD-FMK to label active caspase 1 enzyme in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry. Caspase 1 (ICE):Members of the mammalian caspase family of cysteinyl aspartate-specific proteases play disti…
Magic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…
A novel, far-red fluorescing dye that reveals hypoxic experience of individual cells.
This product is used for labeling of cells to trace multiple generations by flow cytometry.
This product is used for labeling of cells to trace multiple generations by flow cytometry.
This product is used for labeling of cells to trace multiple generations by flow cytometry.
Fastest, most potent broad spectrum caspase inhibitor.
Green Flourescent Caspase-3/7 Apoptosis assay for live cell assays. Analysis by flow cytometry, microscopy or fluorescence microplate
Pan Caspase, broad spectrum caspase, apoptosis inhibitor
Red Flourescent Pan Caspase Apoptosis assay for cell based assays
Red Flourescent Caspase 1 Cell death assay for cell based assays
Red Flourescent Caspase 8 Cell death assay for cell based assays
Green Flourescent Caspase 1 Cell death assay for cell based assays
Green Flourescent Caspase-3/7 Apoptosis assay for live cell assays. Analysis by flow cytometry, microscopy or fluorescence microplate
Green Flourescent Pan Caspase Cell death assay for cell based assays
