LC-MS Products & Reviews

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LC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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HLD PD03 Portable Dry Helium Leak Detector

Agilent Technologies

The Agilent HLD PD03 Dry Leak Detector uses a mass spectrometer tuned to detect helium, which is used as a tracer gas to locate and/or measure very small leaks in enclosed devices or systems. The compact, multi-use HLD PD03 is both a precise instrument and a robust workhorse, featuring an easy-to-use touch screen interface and menu structure that quickly connect users to powerful capabilities. Built-in application setups short…

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MS120 Rotary Vane Pump

Agilent Technologies

MS120 is the roughing (foreline) pump of choice for LC/MS instruments, designed for high pumping speed, low power consumption, and high stability in the 10-2 mbar pressure range Due to the outstanding performance of this roughing pump, there is no need for multiple roughing pumps operating in parallel. The packaging and cart like design allow for a quick and easy installation. The pump is equipped with a built-in Quiet Cove…

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Turbo V source

SCIEX

The Turbo V source is considered the gold standard in mass spec ionization. The patented orthogonal design delivers outstanding ionization efficiency and robustness across many applications, covering flow ranges of 5 uL/min to 3 mL/min. This renowned ion source acts as the foundation on which SCIEX mass spec systems are built and serves as the inspiration for many of the ion sources that followed.  

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IonDrive Turbo V source

SCIEX

The IonDriveâ„¢ Turbo V source increases the capacity of the legendary Turbo V source, maintaining the simple orthogonal design but with higher capacity heaters and a wider sweet spot for enhanced sensitivity.

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OptiFlow Turbo V source

SCIEX

The robustness and simplicity you’ve come to expect from a traditional analytical flow can now be experienced in your high-sensitivity microflow and nanoflow analyses. We have made this possible with standard size finger-tight fittings, and a new single-click source interface – allowing you to effortlessly connect your LC, column, and mass spec. The OptiFlow source is equipped with intelligent probe recognition technology t…

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Metabolite Identification (Met ID) for Oligonucleotides

ChemPartner

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

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EXP® Ti-lok™ Fitting

Optimize Technologies, Inc.

The EXP Ti-lok Fitting features a two-stage locking mechanism ideal for PEEK-clad or sleeved fused silica, such as PEEKsil™ tubing. The two-stage fitting features a patented auto-adjusting titanium hybrid ferrule that seats in any port. The titanium collet locking mechanism provides a second grip point to even the pressure load over the tubing and not crush the silica. The incorporated rear collet locking mechanism is not remo…

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Deformulation and Reverse Engineering

Alfa Chemistry

Alfa Chemistry’s Deformulation and Reverse Engineering Services provide analysis of product composition, material structure, and formulation using qualitative and quantitative techniques. The service supports ingredient identification, formulation profiling, and structural analysis to aid product improvement, quality benchmarking, supply continuity, and technical comparison across diverse materials.

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Pharmaceutical Analytical Services

Alfa Chemistry

Alfa Chemistry’s Pharmaceutical Analytical Services offer expert testing and characterization throughout drug development and production. Using a cGMP-compliant laboratory and advanced analytical techniques, we provide biopharmaceutical characterization, impurity profiling, stability assessment, and formulation analysis to ensure product safety, efficacy, and regulatory compliance.

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Syft Tracer Pharm11

Syft Technologies

Syft Tracer Pharm11 redefines genotoxic impurities analysis for compliant pharma and CDMO workflows as fast and easy with no sample preparation. This solution includes next-gen SIFT-MS Syft Tracer, a CTC autosampler, a high-throughput (HTP) inlet, and 21 CFR Part 11 compliant software SyftAuditTracer.

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Syft SafetySure

Syft Technologies

Syft SafetySure is a class-leading solution for rapid, reliable detection of hazardous chemicals such as fumigants and volatile toxic industrial chemicals in workplace settings. It provides reproducible identification and quantification of hazardous chemicals commonly found in workplaces such as methyl bromide, sulfuryl fluoride, chloropicrin, ethylene dibromide, ethylene oxide and phosphine. It's simple to use with no consuma…

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