ADME-Toxicology Products & Reviews

The kit is designed to use with Agilent Seahorse XF Pro analyzer for easily identifying drug-induced mitochondrial toxicity, to de-risk your drug pipeline.  It provides high sensitivity and specificity, reducing false positive and false negatives.  It is applicable to screen compound libraries with a throughput of 80 compounds per plate.  Assay performance metrics Z’ of > 0.5 is achievable following our assay workflow. 

Afla-V AQUA Strip Tests utilize the proven sensitivity and selectivity of VICAM's monoclonal antibodies to accurately detect and measure total aflatoxins (B1, B2, G1 & G2) at levels as low as 2.5 ppb and as high as 50 ppb. Afla-V AQUA eliminates the need for hazardous solvents using a water-based, dilution-free extraction procedure that develops in just 5 minutes. Results are displayed on the digital screen and may also be pr…

for Latex Agglutination and Latex Turbidimetry Immunoassay

Kits to covalently label dead cells, allowing cells with permeable plasma membranes to be excluded from analysis in flow cytometry. A wide variety of dye options for standard flow, spectral flow, and fluorescence microscopy.

With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.

Radio-telemetry monitoring of blood pressure, heart rate, ECG, temperature, activity

Accelerate Drug Discovery with Crown Bioscience's Comprehensive DMPK / ADME Services

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

A biologically relevant and powerful way to assess CD32/FcyRlla induced effects.

The Glucose-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glucose in biological samples.

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

Multiplate live-cell analysis system

ADAM SCC2, a fast, easy and accurate automated somatic cell counter, is composed of fluorescence optic and image analysis software. It can be useful equipment for dairies, smaller labs and veterinary establishments working with somatic cell analysis. It is helpful to the implementation of milk quality control.

ADAM SCC is fully compatible with the Direct Microscope Somatic Cell Count (DMSCC) with the unique image cytometer technology.

Simplify your omics research

Resolve cross-functional pathways

The new standard of excellence in quantitative metabolomics profiling

Unraveling the complexity of disease

Transforming medicine with metabolomics

Decoding lipid-driven biology