Cell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
With their proprietary technology, the iLite® technology Svar can develop Report Gene Assays – that area cleverly designed, sensitive and specific cell based reporter-gene system with luciferase readout. Svar can develop assays for virtually any pharmaceutical target that allow an easy, rapid and accurate test format for a wide range of applications, such as Immunogenicity and Potency assays.
Biotinylated Hyaluronan Binding protein (b-HABP) (versican G1 domain, VG1)
Measure cell invasion activity in a more physiologically-relevant microenvironment
The ideal cell migration assay for high-throughput screening applications
For screening of hyaluronidase inhibitors, and quantification of hyaluronidase activity in cells and other biological fluids.
This guideline describes the design, development, and validation of quantitative assays for proteins and peptides by mass spectrometry.
Combining the sensitivity of a fluorescence-based assay with a microplate format enables a rapid, quantitative readout suitable for high-throughput analysis. In a microplate well, the fluorescent signal can be generated within whole cells, in cell lysates, or in purified enzyme preparations and may then be analyzed by measuring fluorescence intensity from the well without the need for cellular imaging.
Aura® is the particle and aggregate detection system that combines Backgrounded Membrane Imaging which images 100% of your sample to give you count, size, and morphological information, with up to 2 channels of Fluorescence Membrane Microscopy. Identify if particles are protein or not with the first FMM channel and determine if your sample contains lipids, hydrophobic entities, or other aggregates of your choice with a second…
Meet the Gallery Plus Enzyme Master - the first automated enzyme analyzer designed specifically for enzyme assay applications, with flexibility and automation Thanks to custom designed software, all reagent additions, incubations, and measurements are fully-automated, which saves time, eliminates manual error, and improves method robustness. And with reliable instrumentation, you can facilitate a simple method transfer from R…
Meet the Gallery Enzyme Master - the first automated enzyme analyzer designed specifically for enzyme assay applications. Combining robust hardware and new custom designed software, this best-in-class solution delivers fully-automated incubation settings, reagent additions, and precise measurement calculations—all with a touch of a button. This enzyme analyzer offers the smartest (and fastest) way yet to streamline method dev…
The Luminex xMAP INTELLIFLEX System is the newest addition to the xMAP line of instruments. It comes in two configurations: the Luminex xMAP INTELLIFLEX System and the Luminex xMAP INTELLIFLEX DR-SE System. The main differences between the configurations are the dual reporter and side eject features available in the DR-SE configuration.
Celselect™ Slides capture and isolate individual rare cells, or CTCs based on their size
The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.
The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.
Svar offers assistance in gene therapy projects through robust platforms suited for all phases of drug development and experience from immunoassasy product development as well as their CRO services. Svar currently offer cell-based assays for Neutralizing antibody assessment and custom-made immunoassays for Total antibody assessment.
Complement biomarker assays target selected biomarkers of high relevance. These assays are important and well-suited for analyses in drug development and academic research. They stand out with very low cross-reactivity and high specificity as they bind neo-epitopes of cleaved products or complexes, where this is relevant.
In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.
Refeyn's TwoMP mass photometer measures the mass of single biomolecules in solution and without labels - for studies of protein interactions, oligomerisation and macromolecular assembly, and assessment of sample purity.
The TwoMP Auto combines the ease and efficiency of automation with the unmatched sensitivity and simplicity of Refeyn’s molecular mass measurement technology. It frees up operator time and offers enhanced precision, enabling rapid measurement of multiple samples with low sample consumption.
