CytoPakâ„¢ GMP Human IL-2 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, allowing direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.
3Mâ„¢ Harvest RC Centrate Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed to effectively clarify modern cell culture centrates. Centrate clarification using 3Mâ„¢ Harvest RC Centrate Chromatographic Clarifier may provide many benefits including process compression, high product recovery, and improved process economics.
ActiveMax® Streptavidin μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface. Streptavidin is a tetrameric protein providing 4 high-affinity biotin binding sites, which make it possible to fast prepare and customize your own sterile protein/antibody coupled beads for cell based assay, cell sorting, cell therapy process development and manufacturing use.
CytoPakâ„¢ GMP Human IL-7 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, enabling direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.
Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine. IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells.
GMP ActiveMax® Human T Cell Activation/Expansion CD3/CD28 Beads are 5.5 μm magnetic beads coated with GMP-grade CD3/CD28 antibodies, mimicking APC stimulation. Manufactured in a GMP-compliant, animal-free process, they enable in vitro isolation, stimulation, and expansion of T cells (CD3+, CD4+, CD8+, PBMC) for clinical and preclinical research.
ACRO offers two GMP-grade DLL4 proteins, GMP-DL4H27 (Flagship Product) and GMP-DL4H28 (Complementary Product), designed for iPSC cell culture and differentiation applications. While both proteins undergo similar manufacturing processes with minor procedural variations, they are strategically positioned to address distinct user needs.
The 3Mâ„¢ Harvest RC Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed as an efficient option for harvesting and clarification of modern cell cultures. Clarification using 3Mâ„¢ Harvest RC Chromatographic Clarifier may provide many benefits including fewer processing steps, higher yield and lower production time and costs.
Recombinant IL-2 is widely used in cell culture for the expansion of T cells. In cell culture, IL-2 is a frequently used cytokine for the proliferation, differentiation, and increased antibody secretion of B cells as they transform into plasma cells in vitro.
GMP Human Laminin 521 Protein supports feeder-free PSC culture, maintaining growth and stemness without differentiation for over 10 passages. It’s produced in a GMP-compliant, animal-free process with strict QC testing to ensure quality. Designed for clinical research, it enables a seamless transition from preclinical studies to cell therapy applications.
Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseasesreticulum. The dominant mechanism of IL-15 action is known as transpresentation.GMP IL-7 and GMP IL-15 are commonly used in combination for ex vivo expansion of T cells for cellular therapies.
Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa‑18 kDa Th2 cytokine that shows pleiotropic effects during immune responses.Due to its role in the differentiation of certain immune cell types, IL-4 is commonly used in combination with other growth factors to transform induced pluripotent stem cells into dendritic cells in high numbers.
ProVance™ columns are a high-performance disposable chromatography solution to help meet the growing demand for downstream purification. Until now, there has not been a cost-effective Protein A chromatography option for single-use manufacturing facilities. ProVance™ columns combine Grace proprietary incompressible silica with cost-effective Protein A and disposable column hardware.Grace is the world's largest supplier of spec…
A micro-well, plate-based bright field imaging cytometer for 2D and 3D culture using both adherent and suspension cells.
A micro-well, plate-based multi-channel bright field and 3 fluorescent channels imaging cytometer for 2D and 3D culture using both adherent and suspension cells.
A breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers
Access crystallization and formulation information at mL scale with the new Crystalline PV/RR
Advanced crossflow (AXF) mixing has solved the problem of how to efficiently create the highest quality micro and nano-spheres, emulsions, and crystals around a chosen size with a robust, cost-effective, scalable technology.
Our engineers designed the rCPC platform for pilot-scale purification tasks within a laboratory environment. It is ideal for all batch sizes, smaller or larger, or campaign type of research work, and continuous-batch production. To accommodate a user-friendly operation, RotaChrom offers a turn-key solution package for semi-automated solvent handling (preparation and recovery) upon request. rCPC can be utilized as an at-line p…
RotaChrom’s iCPC platform is the largest commercially available Centrifugal Partition Chromatography instrument in the world. Designed for industrial-scale purification projects in continuous batch operation mode, this device is by far the most cost-effective industrial-scale chromatography platform available on the market. It has the capacity to process hundreds of kilograms of crude input material per month.The iCPC uses si…
The pCPC is a tailor-made system by RotaChrom. It is a combination of the iCPC and a solvent preparation, recovery and regeneration system. It also delivers a proprietary automated biphasic solvent system preparation platform, providing a continuous feed to our iCPC instrument.pCPC encompasses a fully integrated production platform where complete solvent handling is provided beside the iCPC’s purification solutions. The syste…
Add even more to your production with pCPC combined with the Heivap platform. This is a complex solution which enables complete solvent handling and allows the elimination of solvents and final polish of the product. The strategic partnership RotaChrom entered into with Heidolph comes with the possibility to combine the pCPC with Heidolph Heivap platform. The scaled-up and extended system provides a versatile solution, while…
The Phi-TEC I is an adiabatic calorimeter that enables the characterization of thermal runaway hazards during process development and scale-up. The Phi-TEC I replicates industrial (large volume) conditions on a lab-scale, enabling thermal runaway hazards to be characterized safely and efficiently.
The Phi-TEC II is an adiabatic calorimeter, which supports the use of low Phi-factor test cells. This allows for manufacturing plant conditions to be fully replicated on a lab-scale thus allowing thermal runaway risks to be simulated and assessed.
