Scale-up Products & Reviews

The NucleoCounter® NC-202™ automated cell counter is our 3rd generation cassette-based image cytometer. Featuring improved hardware and new NC-View™ software, we take precision, speed and data management to new levels.

The Via2-Cassette™ is our unique cell sampling device, eliminating human error by combining cell sampling, staining and loading into a single press on a piston. Individually volume-calibrated, it guarantees the highest precision in cell counting. The Via2-Cassette™ is a disposable plastic unit containing the fluorescent dyes used for analysis to ensure user safety and operational ease.

NucleoCounter® instruments provide platforms for determination of viability and cell count as well as advanced image analysis of yeast, veterinary semen, insect cells and mammalian cells, both primary cells and cell cultures, including cells in aggregate or microcarrier cultures.

The NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence imaging to characterize cell properties. The NC-3000™ can perform high-speed cell count and viability analyses and it includes plug-and-play analytical assays of mammalian, yeast and insect cells. Pre-defined assays include a unique 5-minute cell cycle assay, a selection of apoptosis assays and a GFP transfection efficiency assay.

A micro-well, plate-based multi-channel bright field and 4 fluorescent channels imaging cytometer for 2D and 3D culture using both adherent and suspension cells.

The Thermo Scientific Pharma 11 is a unique, flexible twin screw extruder for hot melt extrusion and twin screw granulation.

DASGIP Parallel Bioreactor Systems for R&D and process development in both cell culture and microbiology allow for advanced bioprocess control and automation. Parallel processing, precise control of all relevant parameters, user-defined profiles and innumerable automation features result in accelerated and highly efficient process development. Our DASware software solutions support DoE, process historians and comprehensive…

Twin-screw extruders are well-established and used in a wide variety of food, polymer, and pharmaceutical applications to efficiently develop and produce high-quality products using a continuous process.  The modularity of the Thermo Scientific™ Process 11 Twin-screw extrusion equipment provides great flexibility in designing a process to accomplish your food process development goals.

YMC HT Glass Columns are specially designed to accommodate the stringent requirements of high-temperature liquid chromatography applications. Capable of performing efficiently at temperatures up to 70 °C, these columns are perfectly suited for a broad spectrum of purification tasks, particularly in biochemical liquid chromatography (BioLC), where high temperatures are pivotal.

From laboratory to pilot scale, YMC offers reliable, high quality glass columns for all kind of application areas.

YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling.

Does your application require customised pilot columns? With YMC Pilot columns, customised versions can be constructed to address your needs. Of course standard dimensions are available, too!

A breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers

Chemical process safety by design.

Improve reaction understanding with real-time in situ analysis.

Unattended, representative sampling for a wide range of chemical reactions.

Reaction and process understanding with real-time in situ analysis.

The Celsius ® S3 Benchtop System is a laboratory instrument made to evaluate freeze & thaw processes of new drug candidates in single-use bags with full scalability to production-scale Celsius ® platforms (FFT, FFTp and CFT).

The XcytoMatic® 40 (XM40™) is a high-throughput cell density and viability analyzer that can run 24 samples in under 14 minutes. The variation between cell counts for these samples is under 3%. If scale-out and scale-up is a concern, you can trust each XM40™ instrument in your production to deliver the same quality results.

The Phi-TEC I is an adiabatic calorimeter that enables the characterization of thermal runaway hazards during process development and scale-up. The Phi-TEC I replicates industrial (large volume) conditions on a lab-scale, enabling thermal runaway hazards to be characterized safely and efficiently.

The Phi-TEC II is an adiabatic calorimeter, which supports the use of low Phi-factor test cells. This allows for manufacturing plant conditions to be fully replicated on a lab-scale thus allowing thermal runaway risks to be simulated and assessed.

Developed with real world experience and customer feedback at the forefront of the design, the SNAP ® laboratory column range provides effective hardware solutions for liquid preparative chromatography.

Evolve ® Process Columns have been designed specifically for use in biopharmaceutical applications. Available in eight diameters, Evolve ® Process Columns provide cost effective, scalable, high performance technology suitable for use in both pilot and production scale chromatographic processes.

3M™ Harvest RC Centrate Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed to effectively clarify modern cell culture centrates. Centrate clarification using 3M™ Harvest RC Centrate Chromatographic Clarifier may provide many benefits including process compression, high product recovery, and improved process economics.

The 3M™ Harvest RC Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed as an efficient option for harvesting and clarification of modern cell cultures. Clarification using 3M™ Harvest RC Chromatographic Clarifier may provide many benefits including fewer processing steps, higher yield and lower production time and costs.