HTS Assay Kits Products & Reviews

Three kits to cover a wide range of cAMP concentrations.After the introduction of IP-One, the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity, the optimization of cAMP assays with the new HTRF® acceptor d2 offers a complete GPCR platform.The upgraded cAMP dynamic 2 and cAMP femto 2 assays, along with the new cAMP HiRa…

The Amnis NFkB translocation kit includes the conjugated antibody Anti-Hu NFkB (p50) Alexa Fluor 488, the nuclear stain 7-AAD along with the fixation solution, assay buffer and permeabilization buffer to rapidly detect and quantitate NFkB's translocation from the cytoplasm to the nucleus. Nuclear Factor kappa B (NFκB) transcription factor plays a central role in regulating many key processes in mammalian cells, including diff…

Application The Cytotoxicity Detection KitPLUS (LDH) is a fast, sensitive, and simple method to quantitate cytotoxicity/cytolysis based on the measurement of LDH activity released from damaged cells using the 96-well or 384-well plate format. The kit can be used in many different in vitro cell systems when damage to the plasma membrane occurs. For example: Detection and quantification of cell-mediated cytotoxicity. Deter…

The passive reference dye can be added to fluorescence-based quantitative PCR (qPCR) assays to compensate for non-PCR related variations in fluorescence. Product comes in 10 vials of 100 µL. 1mM for controlling the final dye concentration.

Gyrolab® Bioaffy™ 4000, the newest member of the Gyrolab Bioaffy family, offers 2-6 fold extended sensitivity for PK and biomarker analysis compared to Gyrolab Bioaffy 1000.

Cyto-Cellect™ Human IgGK Detection Kit offers a sensitive and robust assay for the detection of human IgG antibody secretion, ideal for streamlining cell isolation and titer determination.

Outstanding GMP QC Testing Services offering Bioassays throughout the lifecycle of drug development, to support the release, stability, and in-process testing of your drug.

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ClinMax Cytokine Detection Kits

NanoLuc® and NanoBiT® Luciferase Substrate for Animal Imaging Studies​

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to make these measurements in a single well of a plate, negating the need to run parallel assays. The first part of the assay is a nonlytic fluorescence assay (CellTiter-Fluor™ Cell Viability Assay) that measure…

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

IRDye 680RD is the near-infrared fluorescent dye of choice for applications in the 700 nm wavelength, especially Western blots, cell-based assays such as the In-Cell Western assay, and small animal imaging experiments.

IRDye Infrared Dyes and near-infrared (NIR) fluorescent imaging deliver enhanced sensitivity due to low background autofluorescence in the near-infrared region, therefore, giving a higher signal to noise ratios.