Drug discovery > Target Discovery Products & Reviews

A direct and efficient set of tools to study a gene’s function by transcriptional interference in its native context

Bioinformatics and Protein Array Services

Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.

Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…

Combining the sensitivity of a fluorescence-based assay with a microplate format enables a rapid, quantitative readout suitable for high-throughput analysis. In a microplate well, the fluorescent signal can be generated within whole cells, in cell lysates, or in purified enzyme preparations and may then be analyzed by measuring fluorescence intensity from the well without the need for cellular imaging.

Cell DIVE multiplexed imaging is an antibody-based hyperplexed technique addressing spatial cell biology and function within the tumor microenvironment. 

High-throughput online automated sample concentration LC-MS solution for water and beverage analysis

Automate complex and time-consuming sample preparation workflows integrated with LC-MS analysis

SU10 is a nanopipette-based tool for efficient and controlled delivery of material (such as CRISPR Cas9 complex, RNA, proteins) into the nucleus or cytoplasm of single cells in a highly automated manner. The CRISPR Cas9 complex can be delivered directly into the nucleus of a specific target cell in a minimally invasive manner through the utilized glass pipette in nanometer range (approx.100 nm).

A high-performance RNA sequencing (RNA-Seq) kit that captures long and short RNAs in a single library, even from limited and low-quality samples. The kit provides all of the components required to make an RNA-Seq library for Illumina platforms. The size of the kit is for 24 reactions.  

A high-performance RNA sequencing (RNA-Seq) kit that captures long and short RNAs in a single library, even from limited and low-quality samples. The kit provides all of the components required to make an RNA-Seq library for Illumina platforms. The size of the kit is for 96 reactions

For use with SEQuoia Complete Stranded RNA Library Prep Kits. Contains 12 unique dual indexed primers supplied in 12 separate vials, for 96 reactions  

For use with SEQuoia Complete Stranded RNA Library Prep Kits. Contains 96 unique dual indexed primers plated in a 96-well plate, for 96 reactions  

Use the SEQuoia RiboDepletion Kit to eliminate cytoplasmic ribosomal RNA (rRNA) and mitochondrial ribosomal RNA (mt rRNA) sequences from an RNA-Seq library.  

25 x 20 µl reactions; kit includes 400 µl Reliance Select 5X reaction mix, 25 µl Reliance reverse transcriptase, Reliance Select random primers, oligo(dT), DNase and buffer, nuclease-free water

100 x 20 µl reactions; kit includes 400 µl Reliance Select 5X reaction mix, 100 µl Reliance reverse transcriptase, Reliance Select random primers, oligo(dT), DNase and buffer, nuclease-free water  

500 x 20 µl reactions; bundle of 5 boxes of 100 reaction kit; includes 2,000 µl Reliance Select 5X reaction mix, 500 µl Reliance reverse transcriptase, Reliance Select random primers, oligo(dT), DNase and buffer, nuclease-free water  

Provides sensitive and specific quantitation of antibodies against four SARS-CoV-2 proteins: nucleocapsid, receptor binding domain, spike 1, and spike 2 viral proteins.  

Combined in a biplate format, Thermo Scientific™ Oxoid™ Columbia CNA Agar/Thermo Scientific™ Brilliance™ GBS Agar enables simple screening of GBS and Gram positive organisms on one plate. 

Boost laboratory efficiency with a universal plate format which is smarter by design  

The Quick-ITS™ Plus NGS Library Prep Kit is the fastest and simplest NGS library prep targeting the ITS region for high-throughput sequencing. 

Phytocannabinoid Mixture 8 (CRM) (Item No. 34043) is a certified reference material mixture that contains neutral, non-acid, forms of compounds that can be isolated from plants in the genus Cannabis.  Included are Δ9-THC, Δ8-THC, cannabinol, cannabidiol, (±)-cannabichromene, cannabidivarin, cannabigerol, and tetrahydrocannabivarin. It is provided as a DEA exempt preparation in an amber ampule in which the headspace has been p…

Melanie™ 9 is a comprehensive easy-to-use software solution for the visualization, matching, detection, quantitation, and analysis of 2D gel electrophoresis (2DE) and Western blot images.

Amersham™ brand Typhoon™ laser-scanner platform provides exceptional data quality through extremely sensitive detection, high image resolution, and a very broad linear dynamic range. These versatile imaging systems support multiple imaging modes, including phosphor imaging, red/green/blue (RGB) and long and short wavelengths of near infrared fluorescence (NIR), as well as optical densitometry (OD) of proteins in stained gels.

Aura® CL systems couples Fluorescent Membrane Microscopy and Backgrounded Membrane Imaging to help you understand what’s in your cell therapy. It detects, counts, sizes, and IDs cellular aggregates and subvisible particles and ID’s cellular from other particles without any machine learning so you can maximize the purity, safety, and efficacy of your therapeutic.