Drug discovery > Target Discovery Products & Reviews

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter System enhances the detection of low-frequency somatic variants in cell-free DNA (cfDNA) by incorporating unique molecular identifiers (UMIs) during library preparation, increasing sensitivity and reducing PCR errors.

Twist's cfDNA Pan-Cancer Reference Standard v2 provides researchers with high-quality, synthetic reference materials to assess and validate liquid biopsy assays, enhancing the detection of low-frequency cancer associated variants.

High Sensitivity. High Conversion. Low-Input

Twist’s RNA sequencing workflows offer a complete NGS solution that produces uniform libraries for RNA sequencing.

Clean up and size selection of DNA and RNA for NGS workflows using magnetic beads

Removal of unincorporated terminators from sequencing reactions using magnetic beads

TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins.

TOYOPEARL AF-rProtein L affinity resin for the capture of mAbs and mAb fragments 

TOYOPEARL Sulfate-650F offers a high binding capacity for IgG across a range of pH values and conductivities

The Transcreener® GDP GTPase Assay Kit directly measures GDP produced during GTP hydrolysis in a homogeneous mix‑and‑read format—no coupling enzymes needed. Compatible with GTPases, GAPs, and GEFs, it supports FP, FI, and TR‑FRET readouts using far‑red tracers to reduce interference. HTS‑ready with excellent sensitivity (Z′ ≥ 0.7), it streamlines screening and profiling workflows.

Simplify your workflow and save valuable laboratory time with the fully automated MACS® Sampler, a perfect extension for the MACS® Matchmaker instrument, allowing you to fully integrate automatization solution for your interaction studies.

With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!

Sino Biological has successfully developed anti-payload antibodies with high purity, specificity, and affinity, which are used for analyzing the plasma/serum PK profiles, DAR values, and drug load distribution of ADC drugs.

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

The Rapid_pH™ Automated 96 pH meter automates the pH measurements of samples in a 96 well format. The Rapid_pH allows samples to be processed in a fraction of the time compared to manual methods avoiding errors in both measurement and data registration. Full automation for well plates and other arrayed containers provides unattended runs and walk-away time.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Biotinylated Human CD20 Full Length, His,Avitag (CD0-H82E3) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus followed by an Avi tag with calculated MW of 36.9 kDa and migrates as 43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

The Scorpion Automated Liquid Handler delivers precise, efficient, and cost-effective liquid handling with versatile labware compatibility and advanced automation for workflows like protein crystallization, re-arraying, and normalization. Its compact design, intuitive software, and ability to handle diverse fluid viscosities and application workflows make it an ideal choice for labs seeking to improve throughput and reproducib…

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.

Cell Line-Derived Xenograft Models, Established multiple in vivo assay systems to evaluate novel anticancer compounds, with each assay specifically designed to understand a drug's mechanism of action, or an individual agent property.

Sirius T3 measures pKa, log P, and the solubility of ionizable drugs and small molecules using sub-milligram quantities of samples.

Biotinylated Human TNF-alpha, His, Avitag (TNA-H82E3) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™), and has a calculated MW of 20.0 kDa. The protein migrates as 21 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

OpenSPR® provides real-time, label-free SPR data at a fraction of the cost of existing solutions. Highly sensitive while being simple to maintain and operate, OpenSPR has been used by hundreds of researchers to generate publication-quality data.