Drug discovery > Pre-Clinical Development Products & Reviews

Radio-telemetry monitoring of blood pressure, heart rate, ECG, temperature, activity

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

Accelerate Drug Discovery with Crown Bioscience's Comprehensive DMPK / ADME Services

Cell Line-Derived Xenograft Models, Established multiple in vivo assay systems to evaluate novel anticancer compounds, with each assay specifically designed to understand a drug's mechanism of action, or an individual agent property.

Accelerate oncology drug development with Crown Bioscience’s PDX Mouse Clinical Trials. Leverage the world’s largest clinically relevant PDX collection to model patient tumor heterogeneity, predict clinical outcomes, discover biomarkers, and optimize drug strategies. Improve clinical translation and reduce attrition with highly predictive, patient-relevant insights.

CrownSyn™: Quantify and visualize drug synergy, antagonism, or additivity in vitro and in vivo with Crown Bioscience’s robust bioinformatics platform—empowering oncology researchers to optimize combination therapies with confidence.

Delve into biomarker discovery and drug development with Crown Bioscience’s next-generation proteomics services—leveraging 4D-DIA technology for deep, reproducible protein profiling and post-translational modification analysis.

Unlock immune insights with Crown Bioscience’s high-throughput flow cytometry—precisely characterize immune cell populations across tissues to elucidate drug mechanisms, assess pharmacodynamics, and optimize immunotherapies.

Accelerate the development of your immuno-oncology drugs with Crown Bioscience’s large panel of immunocompetent syngeneic models.

Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.

PDX Models Empower your research with models that reflect today’s patients and treatments.

Unlock deeper insights into tissue organization and cellular interactions with Crown Bioscience’s spatial biology and digital pathology services, featuring advanced imaging, automated analysis, and high-throughput biomarker screening for applications in cancer research, immunology, and more.

OrganoidXplore™, Organoid Panel Screening Service

Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.

Automated filtration and filling system designed to accurately and aseptically aliquot bulk product into multiple biocontainer bags or bottles.

eXTReme™ Seal features an extra-strong, thick adhesive to minimize evaporation yet removes easily without leaving residue on the plate.

eXTReme™ Seal features an extra-strong, thick adhesive to minimize evaporation yet removes easily without leaving residue on the plate.

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to triggers colitis in mice and rats when administered in drinking water.  

Previously known as SolventTrapSVOC Solvent Recovery System

SPE Disks for Water Extraction

Twin-screw extruders are well-established and used in a wide variety of food, polymer, and pharmaceutical applications to efficiently develop and produce high-quality products using a continuous process.  The modularity of the Thermo Scientific™ Process 11 Twin-screw extrusion equipment provides great flexibility in designing a process to accomplish your food process development goals.

ETHOS™ X microwave extraction line allows quick heating of the cannabis material for terpene isolation. Solvent-free extraction process takes only a few minutes and prevents any thermal degradation often noticed during use of conventional extraction methods. The fresh and characteristic taste of strain-specific cannabis is maintained, and high-quality terpenes are assured. The ETHOS X 2.0 is our latest generation of benchtop…

≥99.9% (titration), crystalline, primary standard, aminopeptidase substrate

≥99% (titration)

lyophilized powder, ≥3 TIU/mg solid