Drug discovery > Lead Discovery Products & Reviews

Twist Bioscience Gene Fragments improve your cloning process by minimizing colony screening. This allows you to save time and money by dramatically reducing cloning and sequencing costs. Think bigger, design on a grander scale, and accelerate your discoveries.

Unleash the full power of a well-designed library. With Twist Bioscience, you are assured that the library you design contains the specific modifications, exactly where you want them, saving you valuable resources for the downstream screening process.

High Throughput Antibody Production by Twist is a gene-to-protein workflow that relieves the costly bottleneck in discovery pipelines by producing tens to thousands of diverse antibodies for screening biophysical and pharmacokinetic properties. You submit the antibody sequence, and we’ll do the rest.

“Allround“ SEC-columns for initial analysis of unknown samples

EcoSEC Elite and EcoSEC HT GPC/SEC Systems enable efficient polymer characterization

TSKgel GPC columns for organic-soluble polymers are packed with spherical particles composed of polystyrene crosslinked with divinylbenzene (PS-DVB)

Ca++Pure-HA is a hydroxyapatite resin used in the chromatographic separation of biomolecules.

TSKgel FcR-IIIA-NPR  affinity columns for direct analysis of mAb activity.

TSKgel Protein A-5PW affinity columns for direct analysis of mAb titer. 

TOYOPEARL NH2-750F offers a high binding capacity across a range of pH values and conductivities

TSKgel SuperQ-5PW is especially suited for industrial purification of oligonucleotides

TSKgel Butyl-NPR hydrophobic interaction columns for analysis of antibody-drug conjugates (ADCs) and as an orthogonal method to analyze protein aggregation, oxidation and deamidations.

The TSKgel DNA-NPR weak anion exchange column is designed to analyze nucleic acids. It routinely separates plasmid isoforms, PCR products and oligonucleotides.

BellBrook Labs delivers bespoke assay development and lead discovery solutions using its Transcreener® HTS platforms. Their expert team optimizes detection of small-molecule modulators for enzyme targets—tailoring buffer, enzyme, and detection conditions to yield strong initial-velocity signals (Z’ 0.7–0.9) in just 2–4 weeks.

The Transcreener® ADP² Kinase Assay Kit universally detects ADP produced by any kinase or ATPase using a direct mix‑and‑read format, eliminating coupling steps. Available in FP, FI, and TR‑FRET formats with far‑red tracers to minimize interference, it's HTS-ready across 96‑, 384‑, and 1536‑well plates with robust Z' ≥ 0.7 performance.

The Transcreener® AMP²/GMP² Phosphodiesterase Assay Kit directly detects AMP or GMP produced by PDEs, ligases, synthetases, ENPP1, and related enzymes using a mix‑and‑read FP or TR‑FRET format—no coupling steps needed. Compatible with 1–1000 µM native substrates, it delivers excellent HTS performance (Z’ ≥ 0.7, ≥100 mP shift) in a one-step, far‑red fluorescence assay.

Titian Software's Mosaic is a leading sample management software solution for life science laboratories, which tracks and manages every step of the sample lifecycle for any type of sample. Mosaic suits any scale of company as its library of ready-to-go modules are configured to meet your specific needs for sample management.

Luminoskan Ascent Microplate Luminometer - Ideal for luminometric research applications The Luminoskan Ascent is a dedicated microplate luminometer, ideal for glow and flash luminometric assays. Application areas of the Luminoskan Ascent Reporter gene assays ATP assays Cytotoxicity Immunoassays DNA quantitation Cell proliferation Phagocytosis Intracellular Ca2+ Enzyme assays Microbiological assays Reactive oxygen assays Advant…

Heating and mixing in 1.5 mL reaction vessels.

Ideal plate for:Cell culture Reactions in 96 Well format up to 1,2 ml i.e. 2,2 ml Storage of samples and transport Round base facilitatesrecovery of samples Compatible with automated systems Can be used with adhesive seal, heat sealing or with theautoclavable Deepwell Mat 96 Autoclavable (121°C, 20 min.)

High performance compact “workhorse” UV/Vis Spectrophotometer for the analytical laboratory. Ideal in a multiuser, multi-application laboratory and for users who require IQ/OQ validation Features Long life Xenon source On-board software for standard and life science applications plus method storage Built in self test diagnostics for GLP instrument performance validation 8 position sample changer as standard Optiona…

A compact benchtop process mass spectrometer for general purpose locations. With a choice of 8 or 16 sample inlet ports, the ProLine can be configured for any application. Interchangeable quadrupole head and electronics with automatic tuning eliminate the need for specialist service technicians.

The UV3000 detector delivers multi-dimensional spectral datra for applications raging from trace analysis to prep, as well as SFC to CE.

The PIKE MIRacle™ is a universal ATR sampling accessory for analysis of solids, liquids, pastes, gels, and intractable materials.

Entry level, two-channel NMR system for proton and carbon operation.