Creative Biolabs Products & Reviews

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Toxicity & Safety Evaluation Services

Creative Biolabs

We offer extensive Toxicity & Safety Evaluation Services to identify potential risks in drug candidates early. Our comprehensive capabilities cover General, Local, Developmental, and Organ-Specific Toxicity (including liver, cardio, and neuro) across numerous animal species, administered via various routes, to characterize drug safety.

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One-Stop CAR-T Therapy Development

Creative Biolabs

Creative Biolabs delivers an end-to-end CAR-T development pathway—from target/scFv discovery, CAR design and vectoring, and cell engineering to in-vitro/in-vivo efficacy, IND authoring, and manufacturing support. Modular and GMP-aligned, the platform spans autologous and allogeneic routes (incl. TRAC/Cas9 and mRNA) to de-risk translation for hematologic and solid tumor programs.

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TCR-Like Antibody Development Solutions

Creative Biolabs

End‑to‑end TCR‑like antibody services targeting peptide–MHC complexes—covering immunogen design, pMHC screening, affinity maturation, developability optimization, and functional validation—with output as IgG, bispecifics, or CAR constructs to access intracellular‑derived antigens.

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Microglia Phagocytosis Assay Service

Creative Biolabs

Microglia are the resident macrophages in the central nervous system (CNS). One of their most important characteristics is their ability to phagocytose, which plays a pivotal role in maintaining brain homeostasis and responding to neurodegenerative diseases. In vitro microglial phagocytosis assays assist in understanding how microglia maintain tissue homeostasis in healthy and disease states.

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One-Stop Solid Tumor Targeting CAR-T Development Solutions

Creative Biolabs

End‑to‑end solid‑tumor CAR‑T development—from antigen/scFv discovery and CAR optimization to cell engineering, in‑vitro/in‑vivo efficacy, and IND support. Incorporates dual/logic‑gated and armored CARs, plus trafficking and persistence enhancements to overcome the tumor microenvironment and improve safety and translation.

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Pharmacology & Pharmacodynamics Studies

Creative Biolabs

Creative Biolabs provides comprehensive PK/PD studies for nonclinical drug evaluation (determining efficacy, safety, dosing). Key features: vast disease models (oncology, neurology, etc.), advanced model tech (CRISPR, humanized mice), integrated PK/PD/safety analysis, and global scientific consultation.

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Human Astrocytes

Creative Biolabs

Primary human astrocytes from Creative Biolabs are isolated from the human brain (cerebral cortex) and can be used to study the function of the CNS and how nerve cells interact.

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Recombinant Human Anti-RSV Antibody (D25)

Creative Biolabs

Recombinant Human Antibody (D25) is capable of binding to RSV, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-RSV mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-RSV mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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Phage Display CaVHHL-S2 Camel Synthetic Single Domain Antibody Library Screening Service

Creative Biolabs

Creative Biolabs provides screening services for the CaVHHL-S2 Camel Synthetic Single Domain Antibody Library but does not sell the library directly. Our advanced M13 pIII fusion phage display technology combined with high-throughput screening platforms enables clients to rapidly identify ideal antibody candidates while resolving issues like extended screening durations and the detection of low-affinity antibodies.

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Neuronal Microelectrode Array (MEA) Assay Service

Creative Biolabs

Microelectrode arrays (MEAs) are a valuable tool for recording and measuring neuronal activity. This technology allows us to evaluate in real time how neuronal activity behaves in an environmentally controlled environment. In addition to spontaneous neuronal activity, electrical or compound stimulation can be performed, and over 40 different parameters are recorded simultaneously.

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Genetic Engineering Model Development Services

Creative Biolabs

Creative Biolabs delivers expert Genetic Engineering Model Development. Their core expertise lies in utilizing CRISPR/Cas9 and TALEN to create precise Knockout, Knockin, Knockdown, and Humanized mouse models, providing powerful, custom tools for advanced disease research and therapeutic testing.

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Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library Screening Service

Creative Biolabs

The Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library serves as a leading resource to expedite the discovery of high-quality antibodies with exceptional specificity. Our library makes efficient identification of optimized drug candidates possible through the use of advanced humanization and randomization technologies, together with a strong high-throughput screening platform.

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TIL Therapy Development Solutions

Creative Biolabs

Configurable TIL therapy development spanning tumor processing, TIL isolation/rapid expansion, functional and phenotypic qualification, and release criteria—paired with manufacturing‑aligned process development and IND documentation to de‑risk scale‑up for solid‑tumor programs.

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Humanized Mouse Models

Creative Biolabs

We specialize in Humanized Mouse Models, overcoming species limits for in vivo human-specific disease studies. We construct diverse systems, including Immune Checkpoint knock-in and PBL/SRC SCID mice, by engrafting functional human cells to power crucial research in oncology, infectious diseases, and immunity.

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Custom Viral Vector Development Services

Creative Biolabs

End-to-end viral vector design and construction covering vector/serotype selection, expression-cassette optimization, cloning, packaging, purification, and QC. Supports AAV, lentivirus, adenovirus, HSV, vaccinia, and baculovirus with scalable production and documentation for in vitro/in vivo studies and IND-enabling work.

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