Status:
ReviewerMember since: 2022
Organization: Yenepoya Research Centre
The instrument is awesome for all the material science applications
Application Area: Drug delivery and biotracking
"The instrument is ultimate!!! I have used it several times for particle size and zeta potential studies and found that it is scientists friendly and gives results in no time. Therefore, I prefer Malvern Zetasizer Ultra for my drug delivery studies and I have published a good impact journal recently in Q1 journal that is Carbohydrate polymers (IF: 10.7)(https://doi.org/10.1016/j.carbpol.2022.119426). Thanks to Malvern Panalytical"
Manufacturer's ResponseThank you for the review and congratulations on the paper.
Status:
ReviewerMember since: 2022
Organization: Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur
Its extremely user friendly, cost effective, 100% reliable, does what it claims.
Application Area:Analysis of Pharmaceutical Samples
"We used this equipment to analyze our formulation in Nano scale which we developed for the treatment of osteoarthritis. Because of the easy layout and working of this instrument, it makes the work done faster. Also, the results are extremely consistent and reproducible. Such characteristics are very important to our pharma industry as it will directly affect the health of the patient consuming the product."
Status:
ReviewerMember since: 2021
Organization: University of Zagreb
Great results, can't live without Zetasizer Ultra
Application Area:Pharmaceuticals
"I am able to achieve precise and reproducible results with it. Also, the device is easy to use and the software is user-friendly. Their application support is readily available in terms of service and interpretation of the acquired data. We never regretted the money invested in this device, it is worth every penny though."
Status:
ReviewerMember since: 2021
Organization: Fluxus, Inc.
Easy to acquire data, analysis tools needs some improvements, great tech support.
Application Area:Analyzing macromolecular and nanoparticle sizes and zeta potential
"The Zetasizer Ultra is a very useful instrument for our R&D activities as we can measure sizes of antibodies and other proteins, assess their aggregation status, and determine also approximate concentrations using the 3 angle measurement capabilities. We are also using the Zeta Potential technique to measure surface charges, mainly for nanoparticles and surface-modified nanoparticles. The system is robust and little instructions are needed for newcomers to DLS/ZP. The "Measure" menu is easy to use, but the data analysis is not well outlined. For example, one can only save ONE custom configuration of data displays, but each user has its own preferences and needs. The selection of the data display parameters and measurement conditions are not well accessible/presentable. Maybe it would be an advantage to be able to split graphs and tables into two different monitors for a better overview and quicker data analysis. Data transfer to a server or between two PCs is not user-friendly at all. Way too many steps, Malvern should find a better solution. The newest software version (V2.0+) does not run on our lap PC and so far nobody could resolve it. The Tech Support from Ulf Nobbmann is excellent, mostly available and feedback is always on the point. Malvern may consider offering the ZS Ultra with two laser wavelengths in the same instrument! We have troubles sometimes with fluorescently labeled species and strong fluorescence reaching the detectors - the filter in front of the BS detector is not sufficient to eliminate all fluorescence if strong emitters are investigated. Would be great to simply switch to laser wavelengths which is not exciting fluorophores. Although DLS/ZP measurements are very straightforward to do on the ZS Ultra, continuous education is needed to become proficient. The Malvern Materials Talks are of substantial help, similar webinars."
Manufacturer's ResponseThanks for the comprehensive review
Status:
ReviewerMember since: 2021
Organization: Illumina Singapore Pte Ltd
Robust and simple to operate.
Application Area:Sizing and zeta potential measurement
"The Zetasizer was a great addition to the analytical instrument available in our lab for sizing and zeta potential experiment. The software is self-intuitive and easy to operate. The customer service is top-notched and the care team will regularly check in on the status or any troubleshooting issues which we might have. Overall, it's a useful instrument to help us generate quick data (in several mins)."
Manufacturer's ResponseThanks for the review and glad to hear you are finding the system intuitive to use and our local distributors are supporting our customers well.
Status:
ReviewerMember since: 2021
Organization: University of Padova
It is amazing, really easy to use and really useful results.
Application Area:Analyze PLGA nanoparticles concentration
"It is a really amazing instrument and really easy to use, even for new students. I obtained really good results, better than the one obtained with the old instrument. It is really innovative."
Manufacturer's ResponseThanks you Greta for your review, nice to hear that our product is easy to use for your students too.
Status:
ReviewerMember since: 2021
Organization: University of Padova
Repeatable and reliable results in a short amount of time.
Application Area:Measurement of size, PDI, zeta potential and concentration of lipid based nanoparticles
"After having the instrument in the laboratory, the technician thoroughly explained its use and functions and differences from Zetasizer nano which is the previous instrument we had in laboratory. I find the new Zetasizer very easy to use. It helps me to differentiate the different nanoparticle populations in my sample. Another good thing is that it has a filter for the fluorescent labeled nanoparticles."
Manufacturer's ResponseThanks for the review and glad to hear you are enjoying the new features.
Status:
ReviewerMember since: 2021
Organization: Università degli Studi di Padova
Easy to use instrument for sensitive analysis. Essential for a drug delivery lab!
Application Area:Drug delivery; nanoparticle size and particle concentration; z-potential
"Zetasizer Ultra is a very easy-to-use instrument that allows for high reproducible measurements. The most amazing feature is the particle concentration analysis which permits to obtain with no much effort well-defined results. The after sales care is very careful and reliable."
Manufacturer's ResponseThanks for your review and happy to hear you are making good use of the particle concentration features.
Status:
Advanced ReviewerMember since: 2020
Organization: Renata Ltd.
Greatly recommended for drug analysis!
Application Area:Dynamic light scattering analysis
"Great results obtained for analysis of mean hydrodynamic particle size and zeta potential of aqueous suspended samples. The samples were suspended and the triplicate experiment yielded consistent results."
Manufacturer's ResponseThanks for taking time to review and we’re glad you are getting the results you need from your Zetasizer Ultra.
Status:
ReviewerMember since: 2021
Organization: Becton Dickinson
Excellent System!
Application Area:Nanoparticle characterization
"This system is very user friendly compared to other particle sizers I have used previously. The method builder allows you to easily analyze several characteristics of our nanoparticles. I would highly recommend this product."
Manufacturer's ResponseWe are glad to hear that our new Zetasizer Ultra is user-friendly Lyndsay.
Status:
ReviewerMember since: 2021
Organization: Instituto Politécnico da Guarda
Can't work with nanotechnology without this instrument.
Application Area:Analyze nanoparticles characteristics
"Super easy to use the product. The software is very simple, although they should add a standard values table for the materials instead the user has to search the values on literature. A super useful instrument for nanoparticle characterization."
Manufacturer's ResponseThank you Jorge for sharing such a positive review. We are glad to hear that our new Zetasizer is easy to use and perfect for nanoparticle characterization.
Status:
ReviewerMember since: 2020
Organization: NanoMalaria Research Unit,Department of Pharmaceutics,Faculty of Pharmaceutical Sciences,Universit
An excellent device for nano-characterization.
Application Area:Characterization of solid nanoparticles
"Easy to use. Reproducible results. Convenient."
Manufacturer's ResponseThank you for the review Samuel, we hope your Zetasizer can help in your research on nanomedicines.
Status:
ReviewerMember since: 2020
Organization: University of Groningen
Easy to work with.
Application Area:Polymer characterisation
"Easy to use and the software thinks along with the user."
Manufacturer's ResponseThanks for the review, we value your feedback and taking your time to provide it.
Status:
ReviewerMember since: 2020
Organization: CSL Behring
No complaints.
Application Area:Particle size analysis
"No complaints - documentation for hourly qualification could be beefed up a little."
Manufacturer's ResponseReply, thanks for the review, however, we are a little bemused by the “hourly qualification” phrase could you contact us to explain further at https://www.malvernpanalytical.com/en/about-us/contact-us/? It’s not normally necessary to perform qualification at such a high frequency. Stay safe.
Status:
ReviewerMember since: 2019
Organization: Johnson Matthey
Easy-to-use yet powerful instrument.
Application Area:Raw material analysis for R&D
"The ZetaSizer Ultra is a dynamic, user-friendly instrument useful for a variety of applications. Malvern provides in-person training on the instrument and its theory that is very useful for newcomers to DLS and ELS measurements. There is a support team that consistently answers quickly with questions regarding interpreting data or other issues with the instrument. All and all a quality instrument and company to work with."
Manufacturer's ResponseAndrew, thank you for the feedback – glad you are enjoying the new system.
Status:
ReviewerMember since: 2019
Organization: MSR
Fantastic bit of equipment. Go for the Ultra not the Pro version.
Application Area:Monitoring protein aggregation
"A very useful piece of equipment. representing good value for money. Had some zeta potential problems during first use but that was down to my sample preparation."
Manufacturer's ResponseMany thanks for the feedback, if you have any particular feedback on our after sales support we would love to hear from you further.
The Zetasizer Ultra is the world’s most capable combined DLS and ELS system, incorporating Non-Invasive Back Scatter (NIBS®) and, uniquely, Multi-Angle Dynamic Light Scattering (MADLS) technology for the measurement of particle and molecular size. NIBS provides the versatility and sensitivity to measure over a wide concentration range, while MADLS permits a higher resolution view into your sample’s size distribution for those critical measurements.
An extension to MADLS affords the ability to directly analyze particle concentration. The measurement of particle concentration is calibration-free, suitable for a wide range of materials, requires no or little dilution, and is quick to use – all of which make it ideal as a screening technique. This is a unique capability of the Zetasizer Ultra which can even be applied to samples such as viruses and VLPs, which were previously very challenging to measure.
The Zetasizer Ultra also provides the highest sensitivity zeta potential and electrophoretic mobility measurements using M3-PALS technology. Our affordable disposable folded capillary cells enable measurements in extremely low volumes, without direct sample-electrode contact, using our patented diffusion barrier method. The information provided by these measurements is an excellent indicator of sample stability and/or propensity to aggregate.
The addition of Constant Current Mode for measuring electrophoretic mobility and zeta potential in high conductivity media reduces errors that can be associated with electrode polarization at higher ion concentrations.