The XF Cell Mito Stress Test is the gold standard for measuring mitochondrial function. Researchers use this critical assay to investigate functional differences among cell types and the effect of drug candidates, and to advance their understanding of cell physiology, disease pathology, and etiology.
The assay reports multiple key parameters, including basal respiration, ATP-linked respiration and spare respiratory capacity (SRC). The SRC metric is often used to evaluate the cells ability to meet an energetic challenge as cells go through activation, differentiation and/or proliferation, and has been implicated in cell fate determination.
For more information, please see the Agilent Seahorse XF Mito Stress Test Kit product website