Member since: 2017
Organization: Minerva Biotechnologies
Easy to use, reproducible data, multi-plate experiment capability.
Application Area: Immuno oncology
"XCelligence system is very easy to setup and use for multi-plate assays. Data is reproducible. ACEA has good after-sales support and have responded quickly and effectively to email/phone calls. Overall satisfied user and multi-plate experiments provide value for money."
Label-free, real-time cell analysis in a 384-well format.
The xCELLigence® RTCA HT instrument uses noninvasive electrical impedance monitoring to quantify cell proliferation, morphology change, and attachment quality in a label-free, real-time manner. The HT (high throughput) model differs from our other xCELLigence instruments in that it uses a 384-well electronic microtiter plate (E-Plate® 384). Up to four instruments can be integrated and controlled by a single analyzer/control unit, giving a total of 1536 wells. Configured for high-throughput screening applications, the RTCA HT model can be used either as a standalone instrument, or integrated into a high-throughput workflow using a Beckman FX (or equivalent) liquid handler for fully automated screening. User friendly software allows for real-time interfacing with the instrument, and includes real-time data display and analysis functions.
By skipping the guesswork associated with end-point assays and eliminating the time- and labor-intensive steps of traditional cell-based assays, real-time cell analysis (RTCA) with the xCELLigence RTCA HT vastly improves efficiency and overall productivity. By eliminating the need for labels/dyes, the physiological relevance of acquired data is maximized. The xCELLigence RTCA HT is currently being used worldwide in industrial and academic labs in applications that include, but are not limited to, the following: