Ultra Performance LC (UPLC) by Waters

Manufacturer Waters
4.5
/
5.0
  |  34 reviews
Making more informed decisions in less time is a universal asset in today's laboratory. Ultra Performance LC™ (UPLC™ ), a new category of separation science pioneered by Waters, will eliminate significant time and cost per sample from your analytical process—while improving the quality of your results. With UPLC technology you benefit from: more data, faster unparalleled sensitivity greater efficiency and confidence in results Waters ACQUITY UPLC™ and nanoACQUITY UPLC™ Systems use uniq... Read more


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Ultra Performance LC (UPLC)
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Average Rating: 4.5
34 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2022

  • Organization: COVALENT LABORATORIES PVT LTD



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Create Working
Rating: 4.7

  • Application Area: Quality control

"Excellent peroformance"

Review date: 15 Dec 2022 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Export Inspection Agency Mumbai



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fast detection and smooth operation, strongly recommended
Rating: 5.0

  • Application Area:CAP & NFM analysis in food products

"Getting repeated and reproducible results for analysis within limit."

Review date: 23 Nov 2021 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Agricutural University of Athens



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy and reliable
Rating: 5.0

  • Application Area:Analyse API

"I use it at work for analysis of APIs. It is easy to use, I don't face any problems. I like the reliability, I don't worry when I have to use it. I dont like that the tubes for mob phase are not transparent, makes it harder to watch if there is bubble presence."

Review date: 15 Nov 2021 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Contract Pharmacal Corp



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Enhanced precision, sensitivity and resolution.
Rating: 5.0

  • Application Area:Analyze degradation product in finished dosage form

"Waters UHPLC increases sample throughput, chromatographic efficiency, resolution between two peaks, sensitivity and decreases run time. The UHPLC system can handle pressure up to 15,000 psi."

Review date: 09 Jan 2021 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Intas pharmaceutical



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use.
Rating: 5.0

  • Application Area:Analytical chemistry

"Easy to run analysis, running time is low, software optimization is good, used with Empower."

Review date: 16 Jun 2020 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Afcona Chemicals Sdn Bhd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good product and saves a lot of time.
Rating: 5.0

  • Application Area:Analyze assays and related substances

"The instrument saves time and reduces the sample needed for 1 injection compared to HPLC. The software is easy to use and is able to track every single change in the injection."

Review date: 17 Mar 2020 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Merck



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Easy, fast, consistent, efficient and with a satisfactory life-time.
Rating: 4.7

  • Application Area:Biomolecules

"Enabling and speeding up complex methods, separating up to 300 species in a very efficient and consistent manner depending on chromatographic column employed."

Review date: 16 Mar 2020 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Tulex Pharmaceuticals Inc.



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Necessary for lab to function.
Rating: 4.0

  • Application Area:Raw material and drug product testing

"The UPLC tend to work as advertised, very quick and efficient. Whenever there is a problem, the service team is here within a few days and helps fix it."

Review date: 21 Nov 2019 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Astrazeneca



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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If you keep using it it works well.
Rating: 3.3

  • Application Area:Formulation of samples

"Great results if you keep using it, does not like to be sat unused. Less slovent required. Poor unbering of vial tray. Difficult with Empower - not user friendly."

Review date: 30 Oct 2019 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Saurashtra University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very good instrument with great functions, love to operate the instrument
Rating: 5.0

  • Application Area:API method validation

"Its really very great operating system for the analysis of active pharmaceutical ingredient. Easy of handling, good data interpretation."

Review date: 22 Mar 2019 | Ultra Performance LC (UPLC)


  • Status:

    Reviewer

  • Member since: 2017

  • Organization: MS



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Perfect for quantification
Rating: 4.3

  • Application Area:analyze large molecules

"Great product, and quick ease of use. Quantification is great and works for small and large molecules."

Review date: 26 Jul 2018 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Vermont Forensic Labs



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great
Rating: 5.0

  • Application Area:Forensic Science

"Great instrument. Easy to use and wonderful customer service"

Review date: 26 Jul 2018 | Ultra Performance LC (UPLC)
  • Status:

    Advanced Reviewer

  • Member since: 2011

  • Organization: King Saud University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Excellent outcomes, nothing possible without this machine.
Rating: 4.3

  • Application Area:Food analysis

"Since 2010, I've used this instrument and have been getting excellent outputs in terms of sensitivity, selectivity, linearity and accuracy. This is really a very robust instrument and very easy to use. Of course the system is little bit expensive but very very reliable and trustworthy instrument. I have already recommended many colleagues to purchase this instrument."

Review date: 21 Feb 2018 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Neon



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Love it
Rating: 4.0

  • Application Area:Small molecules, peptides

"Very good customer service. Easy to use. "

Review date: 06 Mar 2017 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Bristol-Myers Squibb



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Good instrument
Rating: 3.7

  • Application Area:Assay testing

"Easy to use instrument. Easy to take care. User friendly."

Review date: 06 Mar 2017 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: NCTR



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Overall a breakthrough for high quality data for HTS.
Rating: 5.0

  • Application Area:High Throughput Screening, Drug discovery

"Enabling, high quality, easy to integrate. Very much recommend to other."

Review date: 08 Feb 2017 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: NCTR



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Waters UPLC is the best reliable system for metabolomics study
Rating: 4.3

  • Application Area:Analytical chemistry, metabolomics

"The Waters UPLC system is very robust and reliable. The retention time is always within 0.02min, very consistent. It can be run 7 days per week, 24hrs per day."

Review date: 09 Jan 2017 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Tulex Pharmaceuticals



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Generate great results and excellent instrument
Rating: 5.0

  • Application Area:Analysis for assay, impurity, dissolution of the raw materials and finished products.

"The products are very easy to use, I can do the analysis in a very short time and the instrument is robust and precise. The service is right way."

Review date: 23 Dec 2016 | Ultra Performance LC (UPLC)
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: NCTR/ US FDA



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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UPLC is highly recommended
Rating: 4.0

  • Application Area:Analyze metabolites in blood, urine and tissue

"UPLC from Waters is very robust, reliable for use. It can be run 24h a day and 7 days a week. The peak resolution is wonderful."

Review date: 16 Dec 2016 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Tulex Pharmaceuticals



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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The UPLC provides great results in a short period of time
Rating: 5.0

  • Application Area:Analysis for assay, impurity, dissolution of the raw materials and finished products

"The UPLC can produce the data faster and accurately so the projects can be completed on time. The method development, method validation, and the product release can be finished within much shorter time than the HPLC."

Review date: 04 Nov 2016 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2012

  • Organization: CAL



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good UPLC, better results and less trouble. Save costs and good for environment
Rating: 5.0

  • Application Area:pharmaceutical drug

"We achieve very good reproducibility for the test for any subject in pharmaceutical field. It is really worth the investment. Save more and more for long term. Short run with perfect results."

Review date: 18 Dec 2015 | Ultra Performance LC (UPLC)
  • Status:

    Advanced Reviewer

  • Member since: 2014

  • Organization: Boehringer Ingelheim



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Very modern and advanced technology, every laboratory should have this equipment.
Rating: 4.3

  • Application Area:pharmaceuticals R&D

"Very advanced technology and easy to use, decreases your run time from traditional HPLC. Has very good value for money. Saves time, your solvents, sharper peaks with better resolution."

Review date: 07 Dec 2015 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Par Active Technologies Pvt Ltd



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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highly robust, dependable, and reproducible.
Rating: 4.7

  • Application Area:Application for related substances in API

"Better resolution for complex samples It is highly robust, dependable, and reproducible. "

Review date: 11 Sep 2015 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: JNI Medical Corporation



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.3

  • Application Area:Size exclusion chromatographic characterization of conjugate vaccines

"We use Waters Acquity H Class system for both HPLC and UPLC needs of vaccine quality control. Size exclusion columns UH1000, UH2000 help us enormously for conjugate vaccine quality control. Unbound carrier protein content estimation is made possible in the SEC HPLC. We also use UPLC C18 for finding trace process impurities such as formaldehyde and hydrazine. The system is very dependable and user-friendly. Empower software is easy to learn, amazingly useful in processing. Autosampler works excellent. "

Review date: 15 Jul 2015 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: VACSERA - EGY VAC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
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Rating: 4.3
"Easy to use. Accurate. Good after sale service. Best measurements performance. "

Review date: 18 Jun 2015 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: ASTRAZENECA



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Rating: 3.7

Review date: 14 Apr 2009 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Aspen Pharmacare



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.3
"The days of the 20 min run time are over."

Review date: 14 Sep 2007 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Gedeon Richter Ltd.



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.7
"Easy to use."

Review date: 09 Aug 2007 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Biogen idec.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"Easy to connect to mass spec and once set up, it runs reliably."

Review date: 05 Jul 2007 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Exelixis



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.0

Review date: 06 Jun 2007 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Dalian Institute of Chemical Physics



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Rating: 4.3

Review date: 06 Sep 2006 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Sanofi Aventis



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.0

Review date: 05 Sep 2006 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Richter Gedeon Ltd



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Rating: 3.3
"Column thermostat is good for Waters columns only."

Review date: 31 Aug 2006 | Ultra Performance LC (UPLC)
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Bayer CropScience



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.3
"Product is beyond competitor standards."

Review date: 03 Jul 2006 | Ultra Performance LC (UPLC)
Making more informed decisions in less time is a universal asset in today's laboratory. Ultra Performance LC™ (UPLC™ ), a new category of separation science pioneered by Waters, will eliminate significant time and cost per sample from your analytical process—while improving the quality of your results.

With UPLC technology you benefit from:

  • more data, faster
  • unparalleled sensitivity
  • greater efficiency and confidence in results

Waters ACQUITY UPLC™ and nanoACQUITY UPLC™ Systems use unique small particles, very low system volumes and greater throughput to detect more peaks with faster run times.

Ultra Performance LC not only advances what you can accomplish with liquid chromatography analysis. Mass spectrometry’s low dispersion, high-speed detection requirements significantly benefit from the performance characteristics of UPLC.

Product Overview

Ultra Performance LC (UPLC) by Waters product image

Ultra Performance LC (UPLC)

Manufacturer Waters

4.5 / 5.0 | 34 reviews