Twist Universal Blockers
Twist Universal Blockers enhance the specificity of next-generation sequencing (NGS) target enrichment by preventing non-specific hybridization between adapter sequences, thereby improving on-target capture and reducing sequencing costs.
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In NGS workflows, targeted enrichment of genomic regions is crucial for efficient sequencing. Twist Universal Blockers are designed to prevent non-specific hybridization between adapter sequences, thereby enhancing the specificity of target capture. By blocking these non-specific interactions during hybridization, Twist Universal Blockers simplify experimental design, reducing sequencing costs and improving the results of targeted sequencing efforts.
Key features:
- Improved On-Target Capture: Prevents cross-hybridization between TruSeq-compatible adapters, enhancing the performance of target enrichment workflows.
- Unmatched Flexibility: Compatible with various adapter designs and barcode lengths, effective across singleplex and multiplex target enrichment workflows, and improves on-target capture regardless of panel size.
- Maximized Efficiency: Ready-to-use formulation that reduces per-sample sequencing costs and simplifies experimental design and execution.
- Applications:
- Genomic Research: Enhances the accuracy and efficiency of targeted sequencing projects by improving on-target capture rates.
- Agrigenomics: Facilitates the study of specific genomic regions in agricultural species by reducing non-specific hybridization events.
For research use only. Not for use in diagnostic procedures."
