PURELAB® flex 3

Water is essential as a raw material and as a solvent in almost any area of pharmaceutical production you might consider, from drug processing to formulation, manufacture and monitoring. Its purity is therefore of major concern, particularly with respect to microbiological contamination, and is dictated by strict published guidelines at both national and international levels.

In this interactive eBook, we look at several applications of HPLC and LC-tandem mass spectrometry (LC-MS/MS) in pharmaceutical analysis and drug monitoring, but also forensic toxicology, to see how water quality impacts results.

Discover how using ultrapure water improves accuracy, eliminates false readings, and removes sources of variability, as we cover:

• HPLC in pharmaceutical analysis
• How to reduce risk in therapeutic drug treatment and monitoring
• Water in pharma & healthcare: Interactive quiz

In this guide, ELGA shares its expert knowledge about laboratory water and discusses the different options available for achieving a reliable source of purified water. ELGA demonstrates why using the right level of water purity is essential in helping you achieve more consistent, accurate results and how installing an in-house purification system can save you time, money and reduce your environmental impact.

There are many potentially toxic substances in the environment that may contaminate our food, so is vital that measures are taken to protect against these threats to human health. In this application note, ELGA LabWater discusses sensitive new techniques that can accurately detect and measure chemical contaminants in food. ELGA LabWater also explores the benefits of using water purified in a PURELAB® laboratory water purification system for these experiments.

Understanding which foods we should eat for specific health benefits can be difficult – especially as these claims are not always backed up with sufficient scientific evidence. To address this, researchers are analyzing the bioactive compound profiles of different foodstuffs and assessing their potential health-improving properties. In this application note, ELGA LabWater explores the benefits of using ELGA PURELAB® Water Purification Systems in these experiments.

In this application note, discover a new sensitive technique for fingerprint examination allowing forensic scientists to gain more information - such as visualizing hidden fingerprints left on challenging surfaces or analyzing the chemicals in residues.

There are now some 70,000 chemicals on the commercial market, with many others produced each year as intermediates, waste or laboratory chemicals. Many are released into the environment with little or no knowledge of the potential long-term impact on ecosystems. Scientists are developing sensitive techniques that can accurately detect and measure these synthetic compounds so their effects on humans and wildlife can be carefully monitored.

After a skin injury, our body normally triggers a complex wound healing process to repair the damage. Scientists are investigating the use of tissue engineering to mimic the body’s natural processes and help promote the healing of chronic wounds. In a recent study published in Carbohydrate Polymers, scientists create porous 3D scaffolds made of a naturally-occurring polysaccharide derived from crustacean shells and demonstrate their wound-healing potential.

Many emerging viral infections can lead to life-threatening complications involving the central nervous system – including encephalitis or meningitis. But treatment can be challenging, due to difficulties with delivering antiviral drugs across the blood-brain-barrier. A recent study published in Drug Delivery demonstrates the potential of a new inhaled powdered formulation for the direct nose-to-brain delivery of the antiviral drug ribavirin (RBV).

Every day, scientists around the world are using water for a multitude of purposes. But the quality of this reagent is too important to ignore - contaminants and variabilities in laboratory water are putting too many results at risk. This guide shares ELGA’s expert knowledge about laboratory water and water purification technologies. Different levels of water purity are explored and some of the challenges around choosing what to use for a successful experimental outcome at the most economical cost are examined.

Undetectable levels of DNase and RNase in purified water

Discover a range of new technologies and applications for biopharmaceutical development in this special editorial feature