Oasis® Sample Extraction Products by Waters

Manufacturer Waters
4.6
/
5.0
  |  38 reviews
Oasis® sample extraction products are used by separation scientists across the globe to deliver unmatched purity, consistency and quality in their sample analysis. Oasis polymeric products deliver consistent retention and capacity - even if the sorbent dries out. A number of formats are available, including our patented µElution plate. These products deliver: Optimal sensitivity for small molecule and therapeutic peptide analysis Reduced matrix effects Unsurpassed selectivity Cons... Read more


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Oasis® Sample Extraction Products
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Average Rating: 4.6
38 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2018

  • Organization: WV Dept of Agriculture



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great results
Rating: 4.7

  • Application Area: Sample preparation

"It's a great product. It is super easy to use and works great."

Review date: 10 Jun 2019 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: University of Plymouth



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
The best performing among a set of other cartridges.
Rating: 4.7

  • Application Area:Environmental analysis

"The product was highly reliable and easy to use. It was the best performing among a set of other cartridges"

Review date: 17 Jan 2019 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Ohio State University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
It is fine, if it can be cheaper, we may buy again.
Rating: 4.0

  • Application Area:Omic study of whole wheat bread

"When I use prime HLB, there are certain non polar compounds that can not retain on the cartridge but can retain well on C18. And also prime HLB has less loading amount comparing to HLB. However, prime HLB is easier to use."

Review date: 14 Dec 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: marchwood scientific services ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Simple, easy and effective for clean up of matrices for vet drug residue analysis
Rating: 5.0

  • Application Area:Veterinary drug residue analysis

"Easy to use and effective for multi-residue vet drug analysis to meet EC2002/657 guidelines and suitable for a wide variety of sample matrices. Recommended by our Waters representative who kept us updated with any new application note releases relevant for our application (thank you James!)"

Review date: 10 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: University of Verona



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
So far, I experienced only positive aspects after the use of Oasis HLB Prime.
Rating: 4.7

  • Application Area:Plant extract purification

"The purification protocol through OASIS HLB prime cartridges is well described in Waters website and in different experiments carried out by Waters scientists. I have to say that the use of these cartridges is very user-friendly, especially when coupled with the Waters Extraction Manifold system. The main advantage is the avoiding of the first two steps of activation and equilibration of the cartridge, that results in saving at least 10-20 minutes. This can be achieved since the matrix of the cartridge is water wettable (HLB resin presents both lipophilic and hydrophilic retention features). The purification could be made by following one of the two possible procedures and the decision depends on what the user is looking for (i.e. purification from sugars? Purification from phospholipids?...) and the extraction solvent that has been used to extract the metabolites (water, buffer, or methanol). The first strategy (A) occurs when the extracts consist of water or buffer. In this case, sugars and polar metabolites are removed from the sample. The extracts must be passed through the cartridge without any previous operation, then water can be used to wash the cartridge from sugars and other very polar metabolites. This step can be repeated twice. Subsequently, methanol or other less polar solvent can be used for the elution of mildly, less polar metabolites. b) In the other case, methanolic extracts must be supplied with acetonitrile to reach the final ratio of 10:90 of Methanol:Acetonitrile (v/v). Then, the solution can be passed through the cartridge and the flow trough can be collected. The main disadvantage of this point is that you will have a more diluted sample, but phospholipids and other contaminants will remain attached to the cartridge, thus reducing the matrix effects in the following mass spectrometer analysis. Moreover, one can overcome the dilution problem by using a speedvac system to evaporate the solvent and then re-suspend the resulting “powder” with methanol. However, special attention should be taken into account since some metabolites could degrade during the evaporation process. We are still evaluating this point for our analysis. In summary, Oasis Prime HLB might be a precious tool for sample purification, especially from those metabolites which can affect the ionization in mass spectrometry, such as salts, organic acids, sugars and phospholipids. They are also a flexible tool since prime HLB can be used before or after other Oasis cartridges, for example MCX or MAX. I would recommend the use of these cartridges for quantitative analysis in targeted and untargeted metabolomics."

Review date: 09 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: NICC



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    1 out of 5
Price versus usage is not very good
Rating: 3.0

  • Application Area:Solid and liquid extraction in forensic analysis

"We use the 30mg MCX cartridges, but they are very expensive. Also 96 well plates are not very interesting for microelution because sometimes we can not use all the plates and it is difficult to put a label on each column to avoid getting too much sample."

Review date: 09 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: NESTEC S.A.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Very good product for a daily usage
Rating: 4.3

  • Application Area:Smaple Prep Cleaning

"Good reliability and easy to use. Very good for application on polar compounds using ion chromatography."

Review date: 08 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Buyer near Poliambulatorio Dalla Rosa Prati



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Good results, we will order this product in the future.
Rating: 5.0

  • Application Area:Nuclear Medicine

"We use this product in nuclear medicine and radiopharmacy"

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Ohio State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Loosing some compounds that can be retained on C18.
Rating: 4.3

  • Application Area:Analyze small molecules in bread

"Prime HLB is good, but the price is high. Also it is similar to HLB and HLB is cheaper. In my case, I found C18 is much cheaper and gives better results."

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Novartis



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
The tests were fine, to be confirmed in a broader range of samples
Rating: 4.3

  • Application Area:Analytical Chemistry: use the OASIS plate to quench a reaction and elute it prior to MS analysis

"We have been testing a few compounds and it seems to work! We will use Methanol/Acetonitrile mix to elute our compounds of interest. Next step for us would be to automate everything. The goal is to use our TECAN Evo to make all the sample preparation including loading the OASIS plate, washing and eluting through a signal which will trigger a vacuum. We are now waiting for them to provide the parts. If it works in a larger scale, then the assay will become HTS thanks to the OASIS plate."

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products


  • Status:

    Reviewer

  • Member since: 2018

  • Organization: University of Illinois at chicago



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Easy to use
Rating: 4.3

  • Application Area:Peptide desalting and enrichment

"The best part of prime line products is being able to load samples directly without pre-conditioning, which saves time and solvent. It is more "GREEN" than other products."

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: University of Hertfordshire



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Good product.
Rating: 4.3

  • Application Area:Analyse drug and metabolite in tissue samples

"Great product. Works as described for my application. HLB = probably applicable to a wider range of compounds, so less need to buy a wide variety of cartridges."

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Jagiellonian Center for Experimental Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
OASIS = Outstanding, Awesome, Simple, Invaluable , Super!
Rating: 5.0

  • Application Area:Analyze tyrosine derivatives in tissue samples

"I love working with OASIS PRIME HLB! Procedure is simple, reproducible, and highly efficient. I recommend Waters uSPE to everyone!"

Review date: 05 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Laboratori Agroalimentari



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great results
Rating: 5.0

  • Application Area:Analysis fipronil in animal feed samples

"The product is very effective and easy to use. It allows the elimination of a large part of the matrix components and good results of analytes recoveries."

Review date: 04 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: PharmaMar



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Good product that is easy to use and high quality but it did not improve to SLE+.
Rating: 4.3

  • Application Area:Bioanalytical samples extracction

"It is a good product that is easy to use and high quality. Unfortunately we cannot apply to our compound, SLE+ (Biotage) showed a better results in terms of recovery and reproducibility. However, this technique allows us to have other possibilities when developing methods in our laboratory. We would like to make a special mention to the Madrid sales team for their technical support an dedication. Many thanks."

Review date: 04 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: KU Leuven



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
A must-have for each analytical lab
Rating: 5.0

  • Application Area:Analyze bisphenol A in saliva and urine

"There is BPA contamination leaching from the cartridge, but by adding the necessary procedural blanks, we are still able to detect very low levels of BPA (pg/mL)."

Review date: 04 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Michigan State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Good product
Rating: 5.0

  • Application Area:Analyze plasma media and tissue extracts

"I have much better recovery since changing to Oasis prime"

Review date: 04 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Origin Bioanalytical Laboratory



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Solid results with these cartridges for difficult extraction method.
Rating: 4.3

  • Application Area:Extraction and LC-MS/MS analysis of small molecule prodrug and metabolites

"We used Oasis HLB Prime cartridges (1cc) for the extraction and LC-MS/MS analysis of a small molecule prodrug and its 5 metabolites. We needed something that extracted all these compounds with very low matrix effects because four of the compounds shared a common internal standard. Other methods worked for extraction but none removed the matrix effects (presumeably phospholipids) to ensure that all 6 compounds could be validated in plasma. The cartridges are consistent and easy to use and work without conditioning however you'll need a vaccuum manifold to draw sample in without conditioning."

Review date: 03 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: US EPA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Our new go-to SPE
Rating: 5.0

  • Application Area:Steroid analysis

"The Oasis prime product line is an awesome solid phase extraction product line. The ease of use and the variety in the product line has made methods development a breeze. The micro elution plates have reduced the loss in evaporation steps that we had experienced in the past."

Review date: 03 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Almirall, s.a.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Produces great results.
Rating: 4.7

  • Application Area:plasma samples

"good product for our work, excellent results. Ease of use in plasma and Urine drugs."

Review date: 02 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Boehringer Ingelheim Animal Health



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Easiest SPE!
Rating: 4.7

  • Application Area:small molecule extraction in tissue

"Supremely easy, with less steps...excellent results."

Review date: 01 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Donald Danforth Plant Science Center



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Good product and easy to use
Rating: 4.3

  • Application Area:Sample preparation for LC-MS analysis

"The Oasis PRIME HLB column is easy to use and achieve the goal of cleaning up protein digests sample prior to LC-MS analysis. For $2 a piece, it's good for its value. Though I used it interchangeably with C18 colume, I had one experience that the HLB was causing problem for downstream enrichment, but when I use C18 instead, it was fine. So, for each own particular application, some pilot test may be a good idea."

Review date: 01 Oct 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: PRA Health Sciences



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Great Results - will use again.
Rating: 4.7

  • Application Area:LCMS/MS extraction and chromatography

"We look forward to using this again. Thank you so much."

Review date: 28 Sep 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Deutsches Institut für Lebensmitteltechnik e.V.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Good reproducible results
Rating: 4.7

  • Application Area:Analyze veterinary drugs in different food samples

"The Oasis HLB cartidge 6cc 200 mg is very useful for the simultaneous extraction of many different residues of veterinary drugs from various matrices like meat, milk or honey and provides good reproducible results. For the chromatographic separation of these substances, the column ACQUITY UPLC BEH C18 1.7μm 2.1x100mm is well suited."

Review date: 10 Jul 2018 | Oasis® Sample Extraction Products
  • Status:

    Advanced Reviewer

  • Member since: 2012

  • Organization: Abu Dhabi Forensic Laboratory



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Good value vs. price and no blocks
Rating: 5.0

  • Application Area:Extraction of drugs from urine, blood and tissues.

"Very clean extract, high recovery. Easy use with manual or automated extraction"

Review date: 28 Mar 2018 | Oasis® Sample Extraction Products
  • Status:

    Advanced Reviewer

  • Member since: 2015

  • Organization: Microtherapeutic Research Labs



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Simply Awesome!
Rating: 5.0

  • Application Area:Drug Separation from Matrix such as plasma, serum, saliva etc

"It has been helpful in extracting the compounds from sample matrix in an easy way with minimum steps compared to other products which is cumbersome. The extraction efficiency was also very good. Designed in a way that different types of drugs (Acidic, basic and Neutral) can be easily eluted in single cartridge."

Review date: 31 Jan 2018 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Lab. Reg. Salud Publica Comunidad Madrid



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
removes matrix interferences from sample extracts. Useful for LC/MS
Rating: 4.0

  • Application Area:Acrylamide in food.

"Reliably removes matrix components to increase analyte signal. Samples tested: crisps, biscuits and bread. Its ability to remove matrix interferences from a high organic extract (80 % acetonitrile) makes it a very useful tool for sample preparation of biological samples in LC/MS."

Review date: 12 Dec 2017 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: irstea



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Good results to reduce matrix effects
Rating: 4.0

  • Application Area:pesticide analysis in environment

"Study of matrix effects Three types of leaves (alder, poplar and oak leaves – decomposed or not) were spiked at three concentration levels. To limit strong matrix effects, several steps of SPE purification and extract dilution were tested: 2 Oasis Prime HLB: 6 cc 200 mg and 3cc 60mg 3 dilution factors: 1/2, 1/5, 1/10. Signal inhibition decreased to less than 16 % after “Pass through” SPE purification (Oasis HLB 6cc 200 mg) and extract dilution (1/10)."

Review date: 21 Jul 2017 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Santiago de Compostela



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Good choice for a large number of molecules
Rating: 4.7

  • Application Area:Forensic Toxicology

"These cartridges are very useful for the extraction of molecules with different chemical properties at the same time. Also they have very good reproduciblity between assays."

Review date: 22 Dec 2016 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Comedical Trento Italy



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Allows to work with different biological matrices.
Rating: 5.0

  • Application Area:Toxicology and Forensic

"We have developed a protocol for the dosage of drugs of abuse with Oasis PRiME HLB, in hair, blood and serum. Excellent solution for the determination of Thccooh in hair. Very fast, reproducible, excellent sample cleaning, very high recovery. "

Review date: 29 Jun 2016 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Astex Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Good results easy to use
Rating: 3.7

  • Application Area:Sample extraction for bioanalysis

"Both the Ostro filtration plate and the Oasis sample extraction plate have been quickly and easily integrated into our sample extraction procedures. Both provide a consistent improvement over our previous methods."

Review date: 23 Jun 2016 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: CDC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
The cartridges from Waters are the only ones that helped clean-up the samples for our method.
Rating: 5.0

  • Application Area:Analyze metabolites in human urine samples.

"Waters' cartridges produce high quality data and it is a great value for the price."

Review date: 31 May 2016 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: York Bioanalytical Solutions



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Sample clean up

"We tested the Waters Oasis HLB µElution PRiME plate by direct comparison with a standard HLB µElution plate using a validated method for 2 analytes. The ends results were the same, in terms of sample cleanliness and recovery. The flow characteristics were also the same (some positive pressure required, not unexpected with µElution SPE). Time was saved as no conditioning or equilibration was required. As the price is the same as the standard HLB plates, we would not hesitate to use it routinely in our lab in order to save time and money (no solvent required for conditioning). I look forward to using the standard HLB PRiME plate for flow rate comparison."

Review date: 09 Sep 2015 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: University College London



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0

  • Application Area:Sample extraction

"I have been using the Waters Oasis HLB cartridge (both 500mg/6cc and 200mg/6cc) for about three years. I really think this product is the best one I have ever used. My research area mainly focuses on pharmaceuticals and personal care products, including tetracyclines, sulphonamides, DEET, caffeine and triclosan etc. I compared different cartridges and it gives me the best overall recovery rates under complex matrices, such as wastewater, river water and even soil and manure samples. Also the reproducibility is excellent! Recently the Waters company representative told me that HLB cartridges can also get good recovery rate without the step of conditioning, which surprised me a lot! I tested and it is true!"

Review date: 24 Mar 2015 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Dublin City University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Rating: 4.3

  • Application Area:Environmental

"Ease of Use: Relatively easy to use, especially with no issues related to sorbent drying, which makes it particularly easy when getting started on the instrument. After Sales Services: Quick replies to emails and support. Value for Money: Slightly more expensive than others but well worth it. "

Review date: 19 Apr 2013 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Merck



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Rating: 4.3
"Excellent product, does a great job of cleaning up lipids."

Review date: 13 Jun 2011 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: BioScreen Testing Services, Inc.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"Waters products perform very well for difficult sample preparations involving complex matrices and are reliable with respect to reproducibility and quantitation."

Review date: 04 Jun 2010 | Oasis® Sample Extraction Products
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: Sun Chemical



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Rating: 4.0

Review date: 01 Jul 2008 | Oasis® Sample Extraction Products

Oasis® sample extraction products are used by separation scientists across the globe to deliver unmatched purity, consistency and quality in their sample analysis.

Oasis polymeric products deliver consistent retention and capacity - even if the sorbent dries out. A number of formats are available, including our patented µElution plate. These products deliver:

  • Optimal sensitivity for small molecule and therapeutic peptide analysis
  • Reduced matrix effects
  • Unsurpassed selectivity
  • Consistent retention and capacity, yielding the highest SPE recovery
  • Wide selection of sorbents
  • Broad array of formats

Oasis sorbents are available in seven different solid-phase extraction (SPE) chemistries, designed to meet a wide variety of sample preparation needs. These sorbents include:

  • Oasis PRiME HLB
  • Oasis PRiME MCX
  • Oasis HLB
  • Oasis MCX
  • Oasis MAX
  • Oasis WCX
  • Oasis WAX