Status:
ReviewerMember since: 2009
Organization: Alklaloid AD Skopje
Great value for the money as UHPLC instrument
Application Area: Pharmaceutical industry
"When comparing different UHPLC instrument from different vendors, we hit a wall with an analytical method for separating 4 (four) components in finished pharmaceutical product, using UPLC or UHPLC columns. Only Nexera UHPLC 40 series gave us results because of the suitable combination of total system volume, dwell volume and injection volume. It is an instrument that could work both as HPLC and UHPLC, which saves money for every laboratory, it is very rigid and could be used 24/7, and the maintenance is very easy for the end user."
Status:
ReviewerMember since: 2023
Organization: Safeeds
Cost-benefit, easy to use
Application Area:Analyze organic molecules in complex mixtures
"The UHPLC software runs smoothly, very simple to use and with many options. Hadrware itself is robust and easy to change consumable. Auto-check is also something useful."
Status:
ReviewerMember since: 2022
Organization: Food analysis lab
Time consuming and easy handling model
Application Area:Food safety
"As comparing with other products, Nexera series is the best user friendly model I ever used. Customerization is the most important criteria for every post sale user's. In that case, spincotech provide on time Manpower support on customer requirements. "
Status:
ReviewerMember since: 2022
Organization: Standpharm Pakistan (Pvt) Ltd.
Great addition
Application Area:Chromatography
"It is quite good addition in lab, it help in reducing the time for new developments and help in stability studies. Services are good enough."
Status:
Expert ReviewerMember since: 2015
Organization: Amriya Pharmaceutical Industries
Great results and high efficiency
Application Area:Analysis raw materials quantitative and qualitative
"Very fast and accurate results"
Status:
ReviewerMember since: 2022
Organization: Pharmanza Herbal Pvt. Ltd.
A valuable asset for our analytical lab
Application Area:Very robust UHPLC system with ease of use in terms of instrument and software
"We have been using Nexera N-Series for two years and we have many developed and validated methods for phytopharmaceuticals. We get great results in terms of accuracy, precision, robustness etc."
Status:
ReviewerMember since: 2022
Organization: Assistant professor, PBMMEC
Great reproducibility and trustworthy.
Application Area:Phytochemical assay and neurotransmitters
"The UHPLC by shimadzu is an excellent analytical system for quantitative estimation of chemical constituents in the food, plant and animal samples. I use it for estimation of neurotransmitters and plant compounds (Phytochemicals). The system we have here has a diode array and fluorescence detectors which is an efficient set for reproducible results"
Status:
Expert ReviewerMember since: 2015
Organization: Amriya Pharmaceutical Industries
Great results and high performance
Application Area:Quantitative and qualitative analysis of pharmaceutical dosages
"Very accurate and easy to use."
Status:
ReviewerMember since: 2014
Organization: Micro Labs Ltd.
Great out put with less maintenance
Application Area:Pharmaceutical products analysis
"Great instruments, no maintenance, and good to use"
Status:
ReviewerMember since: 2021
Organization: Smithers
Great results, love this instrument and also recommend to others.
Application Area:Sample analysis
"Very high throughput. Highly efficient and highly reproducible. Fast injection. Love this HPLC."
Status:
Expert ReviewerMember since: 2015
Organization: Amriya Pharmaceutical Industries
Very accurate and stable instrument.
Application Area:Quantitative and qualitative analysis
"Very easy to use and very accurate."
Status:
ReviewerMember since: 2020
Organization: biodeal laboratories ltd
Great value for money and easy to use.
Application Area:Analyze pharmaceutical drug substance and drug product
"Shimadzu Nexera series is an integrated machine that work with precision to deliver results for drug analysis in a fast and secure way. It is integrated with a LC solution software that makes data processing faster and easier. The support for the machine, repairs and spares are readily available making it good value for money. "
Status:
Advanced ReviewerMember since: 2020
Organization: National University of Singapore
Great result.
Application Area:Drug discovery system
"Nexera UHPLC and an LCMS-2020 mass spectrometer is a powerful choice for analysis."
Status:
ReviewerMember since: 2020
Organization: ROLAND INSTITUTE OF PHARMACEUTICAL SCIENCES
A must have innovation for every analytical chemist.
Application Area:Analytical chromatography
"AI and IoT based UHPLC is the best choice for pharmaceutical applications."
Status:
ReviewerMember since: 2013
Organization: CLVCE
It is pleasure to work with this instrument.
Application Area:Drug related compounds and impurities
"I obtain high quality LC data with good reproducibility. The sensitivity is perfect."
Status:
ReviewerMember since: 2020
Organization: University of Arizona
Good for testing purities. Hope it can be made better.
Application Area:Separate mixtures of isomers and removing imourities
"It works well for separating the impurities from the analyte before using it for further analysis. However, lacks resolution for isomeric mixtures. 5' and 6' isomers are hard to separate."
Status:
ReviewerMember since: 2020
Organization: The University of Arizona
Good but could be better.
Application Area:Separation
"The separation effectiveness is not as much as expected. Isomers are eluting at the same time but it can separate the other interfering compounds from the isomers that I am interested in and use for further analysis using CZE."
Status:
ReviewerMember since: 2020
Organization: Analyticaone
A lot of features to guide the user to operate the system efficiently.
Application Area:DOA
"The new nexara UPLC has many artificial intelligence features, such as pilot, weight sensor for solvents, and many others which make the use of the system very easy and straight forward. Shimadzu gives very good service and support - the team is available to support us any time."
The Nexera UHPLC series maximizes reliability and uptime with fully unattended workflows that span from startup to shut-down. Operators can set the Nexera to start up at a specified time, so that it can complete auto-purge, equilibration, baseline checks and system suitability in advance, and be ready for analysis before they arrive at the lab. In addition, FlowPilot ramps up the flow rate gradually, reducing the possibility of damage to columns. The Nexera also has auto-diagnostics and auto-recovery capabilities that allow it to monitor pressure fluctuations to check for anomalies.
With remote mobile phase monitoring and integrated consumables management, the system maximizes uptime and reliability. Real-time monitoring of mobile phase levels allows lab personnel to efficiently run batches and respond accordingly if there isn’t enough mobile phase before starting a run. In addition, Nexera tracks consumable usage and sends alerts when parts need replacing, allowing users to keep the system running at peak performance. The Nexera UHPLC series allows analysts to confirm parameters and monitor chromatograms in real time directly from a web browser on their smart device.
The Nexera UHPLC increases efficiency by automating workflows and maximizing throughput analysis. The SIL-40 autosampler can process the entire injection cycle time in as little as seven seconds, and continuous analysis can be carried out on up to 44 MTPs (using 3 plate changers). The SIL-40’s plate changers enable non-stop temperature-controlled analysis of thousands of samples. The Nexera automatically blends mobile phases at any set ratio, which speeds up the preparation of buffer solutions and the dilution of solvents. Because it prepares the exact amounts required for analysis, the Nexera reduces waste and labor.