Nexera 40 Series UHPLC by Shimadzu Corporation

4.6
/
5.0
  |  25 reviews

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Nexera 40 Series UHPLC by Shimadzu Corporation product image
Nexera 40 Series UHPLC
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Average Rating: 4.6
25 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2009

  • Organization: Alklaloid AD Skopje



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great value for the money as UHPLC instrument
Rating: 4.7

  • Application Area: Pharmaceutical industry

"When comparing different UHPLC instrument from different vendors, we hit a wall with an analytical method for separating 4 (four) components in finished pharmaceutical product, using UPLC or UHPLC columns. Only Nexera UHPLC 40 series gave us results because of the suitable combination of total system volume, dwell volume and injection volume. It is an instrument that could work both as HPLC and UHPLC, which saves money for every laboratory, it is very rigid and could be used 24/7, and the maintenance is very easy for the end user."

Review date: 02 Sep 2023 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2023

  • Organization: Safeeds



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Cost-benefit, easy to use
Rating: 4.7

  • Application Area:Analyze organic molecules in complex mixtures

"The UHPLC software runs smoothly, very simple to use and with many options. Hadrware itself is robust and easy to change consumable. Auto-check is also something useful."

Review date: 01 Sep 2023 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Morgan State university



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Very good results
Rating: 4.0

  • Application Area:Compounds

"One of the best HPLC I have ever worked with"

Review date: 23 Mar 2023 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Food analysis lab



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Time consuming and easy handling model
Rating: 4.7

  • Application Area:Food safety

"As comparing with other products, Nexera series is the best user friendly model I ever used. Customerization is the most important criteria for every post sale user's. In that case, spincotech provide on time Manpower support on customer requirements. "

Review date: 30 Nov 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Standpharm Pakistan (Pvt) Ltd.



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great addition
Rating: 4.3

  • Application Area:Chromatography

"It is quite good addition in lab, it help in reducing the time for new developments and help in stability studies. Services are good enough."

Review date: 16 Nov 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: ITC Ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very great results
Rating: 5.0

  • Application Area:Food Testing

"n-series nexera UPLC , it was very simple to use and cost saving for chemicals "

Review date: 15 Nov 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Spinco biotech pvt ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Superb
Rating: 5.0

  • Application Area:Pharma

"I used this product at different labs its very nice and minimal carry over"

Review date: 15 Nov 2022 | Nexera 40 Series UHPLC
  • Status:

    Expert Reviewer

  • Member since: 2015

  • Organization: Amriya Pharmaceutical Industries



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and high efficiency
Rating: 5.0

  • Application Area:Analysis raw materials quantitative and qualitative

"Very fast and accurate results"

Review date: 31 Oct 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Pharmanza Herbal Pvt. Ltd.



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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A valuable asset for our analytical lab
Rating: 4.7

  • Application Area:Very robust UHPLC system with ease of use in terms of instrument and software

"We have been using Nexera N-Series for two years and we have many developed and validated methods for phytopharmaceuticals. We get great results in terms of accuracy, precision, robustness etc."

Review date: 29 Sep 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Assistant professor, PBMMEC



  • Ease of use
    5 out of 5
    After sales service
    2 out of 5
    Value for money
    5 out of 5
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Great reproducibility and trustworthy.
Rating: 4.0

  • Application Area:Phytochemical assay and neurotransmitters

"The UHPLC by shimadzu is an excellent analytical system for quantitative estimation of chemical constituents in the food, plant and animal samples. I use it for estimation of neurotransmitters and plant compounds (Phytochemicals). The system we have here has a diode array and fluorescence detectors which is an efficient set for reproducible results"

Review date: 28 Sep 2022 | Nexera 40 Series UHPLC


  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Food and Drug Administration - DTQAL



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Very user friendly
Rating: 4.0

  • Application Area:ASSAY OF PHARMACEUTICAL PRODUCTS

"Very easy to use"

Review date: 18 Jul 2022 | Nexera 40 Series UHPLC
  • Status:

    Expert Reviewer

  • Member since: 2015

  • Organization: Amriya Pharmaceutical Industries



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and high performance
Rating: 5.0

  • Application Area:Quantitative and qualitative analysis of pharmaceutical dosages

"Very accurate and easy to use."

Review date: 17 Jul 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Micro Labs Ltd.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great out put with less maintenance
Rating: 5.0

  • Application Area:Pharmaceutical products analysis

"Great instruments, no maintenance, and good to use"

Review date: 30 Mar 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Smithers



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, love this instrument and also recommend to others.
Rating: 5.0

  • Application Area:Sample analysis

"Very high throughput. Highly efficient and highly reproducible. Fast injection. Love this HPLC."

Review date: 04 Feb 2022 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UNIQUE PHARMACEUTICAL LABORATORIES



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Nice instrument
Rating: 5.0

  • Application Area:NDMA Analysis

"Nice and robust system"

Review date: 20 Nov 2021 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Deccan Fine Chemicals



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent
Rating: 5.0

  • Application Area:Pesticide analysis

"Excellent product"

Review date: 16 Nov 2021 | Nexera 40 Series UHPLC
  • Status:

    Advanced Reviewer

  • Member since: 2005

  • Organization: University of Tokyo



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Average
Rating: 3.0

  • Application Area:Biomolecule analysis

"Average compared to other company's ones."

Review date: 24 Sep 2021 | Nexera 40 Series UHPLC
  • Status:

    Expert Reviewer

  • Member since: 2015

  • Organization: Amriya Pharmaceutical Industries



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very accurate and stable instrument.
Rating: 5.0

  • Application Area:Quantitative and qualitative analysis

"Very easy to use and very accurate."

Review date: 16 Jul 2021 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: biodeal laboratories ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great value for money and easy to use.
Rating: 5.0

  • Application Area:Analyze pharmaceutical drug substance and drug product

"Shimadzu Nexera series is an integrated machine that work with precision to deliver results for drug analysis in a fast and secure way. It is integrated with a LC solution software that makes data processing faster and easier. The support for the machine, repairs and spares are readily available making it good value for money. "

Review date: 25 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: National University of Singapore



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result.
Rating: 5.0

  • Application Area:Drug discovery system

"Nexera UHPLC and an LCMS-2020 mass spectrometer is a powerful choice for analysis."

Review date: 24 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: ROLAND INSTITUTE OF PHARMACEUTICAL SCIENCES



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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A must have innovation for every analytical chemist.
Rating: 4.3

  • Application Area:Analytical chromatography

"AI and IoT based UHPLC is the best choice for pharmaceutical applications."

Review date: 24 Dec 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: CLVCE



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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It is pleasure to work with this instrument.
Rating: 4.0

  • Application Area:Drug related compounds and impurities

"I obtain high quality LC data with good reproducibility. The sensitivity is perfect."

Review date: 26 Apr 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of Arizona



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good for testing purities. Hope it can be made better.
Rating: 4.3

  • Application Area:Separate mixtures of isomers and removing imourities

"It works well for separating the impurities from the analyte before using it for further analysis. However, lacks resolution for isomeric mixtures. 5' and 6' isomers are hard to separate."

Review date: 04 Mar 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: The University of Arizona



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good but could be better.
Rating: 4.7

  • Application Area:Separation

"The separation effectiveness is not as much as expected. Isomers are eluting at the same time but it can separate the other interfering compounds from the isomers that I am interested in and use for further analysis using CZE."

Review date: 04 Mar 2020 | Nexera 40 Series UHPLC
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Analyticaone



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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A lot of features to guide the user to operate the system efficiently.
Rating: 5.0

  • Application Area:DOA

"The new nexara UPLC has many artificial intelligence features, such as pilot, weight sensor for solvents, and many others which make the use of the system very easy and straight forward. Shimadzu gives very good service and support - the team is available to support us any time."

Review date: 10 Feb 2020 | Nexera 40 Series UHPLC

The Nexera UHPLC series maximizes reliability and uptime with fully unattended workflows that span from startup to shut-down. Operators can set the Nexera to start up at a specified time, so that it can complete auto-purge, equilibration, baseline checks and system suitability in advance, and be ready for analysis before they arrive at the lab. In addition, FlowPilot ramps up the flow rate gradually, reducing the possibility of damage to columns. The Nexera also has auto-diagnostics and auto-recovery capabilities that allow it to monitor pressure fluctuations to check for anomalies. 

With remote mobile phase monitoring and integrated consumables management, the system maximizes uptime and reliability. Real-time monitoring of mobile phase levels allows lab personnel to efficiently run batches and respond accordingly if there isn’t enough mobile phase before starting a run. In addition, Nexera tracks consumable usage and sends alerts when parts need replacing, allowing users to keep the system running at peak performance. The Nexera UHPLC series allows analysts to confirm parameters and monitor chromatograms in real time directly from a web browser on their smart device. 

The Nexera UHPLC increases efficiency by automating workflows and maximizing throughput analysis. The SIL-40 autosampler can process the entire injection cycle time in as little as seven seconds, and continuous analysis can be carried out on up to 44 MTPs (using 3 plate changers). The SIL-40’s plate changers enable non-stop temperature-controlled analysis of thousands of samples. The Nexera automatically blends mobile phases at any set ratio, which speeds up the preparation of buffer solutions and the dilution of solvents. Because it prepares the exact amounts required for analysis, the Nexera reduces waste and labor. 

Product Overview

Nexera 40 Series UHPLC by Shimadzu Corporation product image

Nexera 40 Series UHPLC

Manufacturer Shimadzu Corporation

4.6 / 5.0 | 25 reviews