Q-TOF LCMS-9030
Offering effortless Q-TOF LCMS performance, the LCMS-9030 allows users to perform critical qualitative and quantitative analysis with genuine confidence and ease.
Q-TOF LCMS-9030
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The LCMS QTOF 9030 stands out for its exceptional high-resolution mass spectrometry, delivering accurate and sensitive results. Its intuitive interface and efficient workflow boost productivity, and its advanced data acquisition capabilities offer in-depth molecular analysis. It remains a valuable tool for complex research tasks.
Biopharma
As a user of the LCMS QTOF 9030, I’ve been thoroughly impressed with its performance and versatility. The high-resolution mass spectrometry capabilities offer exceptional accuracy and sensitivity, making it a valuable tool for complex quantitative and qualitative analyses. The system’s user-friendly interface and streamlined workflow significantly reduce setup time and enhance productivity. I particularly appreciate the instrument’s robust data acquisition and analysis features, which provide detailed insights into molecular structures and dynamics. Overall, the LCMS QTOF 9030 has proven to be a powerful asset in our lab, delivering reliable results and supporting a wide range of research applications.
Review Date: 11 Sept 2024 | Shimadzu Corporation
Great results and accurate.
Biopharmaceutical
Great results and accurate
Review Date: 20 Jul 2021 | Shimadzu Corporation
Great results and good service
Pharmaceuticals
Lot of applications and ease of doing complex things at one time.
Review Date: 11 Apr 2019 | Shimadzu Corporation
We are using it in a daily basis and would not replace it with another machine.
Environmental
Very easy to use instrument, providing excellent resolution.
Review Date: 15 Mar 2019 | Shimadzu Corporation
Perfect combination.
Food Safety
Low detection limit. High mass accuracy. Easy to use. Good support
Review Date: 15 Mar 2019 | Shimadzu Corporation
Shimadzu's spend in R & D shows the inventsment in their products. They're bullet proof.
Research and Development
Always recommend SHIMADZU to other customers as their products are robust and reliable with great after sales support
Review Date: 15 Mar 2019 | Shimadzu Corporation
Next era of TOF technologies.
Forensic sciences
Formula predictor is very easy to use and works great. Speed and resolution is the biggest advantages of this device. It is like hybrid of LCMSMS and Q-TOF system.
Review Date: 15 Mar 2019 | Shimadzu Corporation
It is a very nice instrument.
Lipids analysis
The instrument is a quadrupole time-of-flight mass spectrometer with a very fast acquisition rate and a very high sensitivity.
Review Date: 18 Feb 2019 | Shimadzu Corporation
The LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with powerful TOF architecture to transform high mass accuracy workflows by achieving high-sensitivity, high-speed, and high-resolution detection.
The LCMS-9030 Q-TOF delivers outstanding mass accuracy over a wide mass range, enabling users to consistently produce accurate identification results. The need for infrequent calibration makes it easy to achieve high mass accuracy over long periods. High efficiency ion guides, quadrupole, and collision cell enable high sensitivity for the detection of trace level compounds. And, due to its robust platform, the LCMS-9030 achieves reproducible quantitative analysis over longer periods of time.
The LCMS-9030 incorporates the patented ultrafast technologies used in Shimadzu LC-MS/MS platforms to deliver outstanding speed. Innovative TOF architecture, such as the iRefTOF reflectron technology, which generates an ideal reflectron field, enables precise, ultra-fast pulsing of ions into the flight tube and ideal reflection back to the detector. The result is high-speed data acquisition compatible with the high-throughput laboratory.
A fast and simple workflow for mAb post-translational modifications study using LCMS-9030 Q-TOF
During drug development, it is crucial to closely monitor the changes in the post-translational modification (PTM) amino acid relative site abundance percentage values, such as methionine (M) oxidation or asparagine (N) deamidation, as it can impact the efficacy, stability and immunogenicity of monoclonal antibodies (mAbs).
Explore a simple and straightforward workflow to quantify the amino acid site relative abundance using peptide mapping analysis. Discover how a Shimadzu LCMS-9030 QTOF mass spectrometer coupled with Protein Metrics software provides high mass resolution to accurately identify, separate, and quantify the modified peptides with small mass shift differences. The use of peptide mapping analysis for PTM study can provide valuable insights into the mAbs characteristics to support early to late-stage drug development.
Multi-charged ion analysis of intact antibodies using a Q-TOF mass spectrometer
Explore the use of mass spectrometry for characterizing antibody drugs, including monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs). Shimadzu examines the challenges of structural heterogeneity in antibody production and introduces examples of analyzing pseudo ADCs with MALDI-TOF MS and trastuzumab with its LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer. The LCMS-9030 integrates quadrupole technology with TOF capabilities for accurate mass measurement. Techniques like charge deconvolution aid in molecular weight and glycosylation analysis, ensuring drug quality and efficacy.
Revealing the invisible web: Solutions for an efficient analysis of PFAS
In this application note, Shimadzu discusses the challenges and solutions for per- and polyfluorinated alkyl substances (PFAS) analysis, including how to avoid sample contamination and sample loss, and how to optimize data processing. PFAS are a family of synthetic chemicals resistant to degradation and accumulate in the environment and living organisms, posing risks to humans and ecosystems. Shimadzu’s LC-MS/MS instruments and LabSolutions Insight software can streamline PFAS analysis, automate QA/QC flagging, and ensure data integrity. The use of PFAS-free containers, avoiding storing samples in glass, and SPE cartridges tests are necessary to avoid sample contamination.
Solutions for infectious diseases
In this application note, Shimadzu Corporation introduces three analytical instruments to evaluate infectious diseases caused by harmful microorganisms: liquid chromatography-mass spectrometer (LC-MS), matrix assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS), and gas chromatography-mass spectrometer (GC-MS). The note highlights the rise of bacterial infectious diseases in the past 10 years, emphasizing the importance of investigating and examining these infections.
Managing the risk of nitrosamines in medicinal drugs
Nitrosamines, also known as N-nitrosamines, refer to any molecule with a nitroso functional group (NO⁺) bonded to a deprotonated amine. Nitrosamine impurities are of particular concern as there is evidence that they can be carcinogenic, and therefore their presence in medicines is considered unacceptable.
In this free eBook, discover a range of ultra-fast mass spectrometry technologies for the quantification of trace levels of nitrosamine impurities from various drug substances, drug products, and solvents.
This eBook will also cover:
- Sartan analysis
- Metformin analysis
- Other API analyses
- Residual solvent analysis
High-resolution mass spectrometry and fluorescence detection using Restek’s Raptor Polar X Column and Protein Metrics’ Software Suite
In this application note, Shimadzu demonstrates how the LCMS-9030 promises excellent mass accuracy for N-linked glycans on several proteins and explains how Restek's Raptor Polar X, an innovative hybrid ion exchange/HILIC column, is an ideal column for glycans.
Monoclonal Antibody Workflows on the Shimadzu Q-TOF LCMS-9030 Using the Protein Metrics Software Suite
Accurate characterization of monoclonal antibodies is essential to the development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess production, product formulation, and product dosage. In this application note, learn how the new Shimadzu Q-TOF LCMS-9030 can be used to characterize the recombinant human IgG1ҝ NIST mAb reference standard as a model of biotherapeutic monoclonal antibodies.
LCMS-9030 Quadrupole Time-of-Flight Liquid Chromatograph Mass Spectrometer
The LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer integrates fast and sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed, and effortless performance enable the LCMS-9030 to address qualitative and quantitative challenges with genuine confidence and ease.
LCMS-9030 Quadrupole Time-of-Flight Liquid Chromatograph Mass Spectrometer
This video provides an overview of the LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer.
Latest Advancements in Biopharmaceutical Research and Technologies
Discover a range of new technologies and applications for biopharmaceutical development in this special editorial feature
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