Revealing the invisible web: Solutions for an efficient analysis of PFAS

In this application note, Shimadzu discusses the challenges and solutions for per- and polyfluorinated alkyl substances (PFAS) analysis, including how to avoid sample contamination and sample loss, and how to optimize data processing. PFAS are a family of synthetic chemicals resistant to degradation and accumulate in the environment and living organisms, posing risks to humans and ecosystems. Shimadzu’s LC-MS/MS instruments and LabSolutions Insight software can streamline PFAS analysis, automate QA/QC flagging, and ensure data integrity. The use of PFAS-free containers, avoiding storing samples in glass, and SPE cartridges tests are necessary to avoid sample contamination.