mosquito® HV genomics
Unlocking the potential of genomics with miniaturized, automated liquid handling
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A great instrument for miniaturization of workflows
NGS, WGS of pathogens, ISO accredited environment
The instrument is very user friendly. Custom workflows can be programmed by lab technicians after an introduction, which is not possible for many other devices. While we use workflows provided by SPT Labtech, we also set up additional programs to make the daily life in the lab easier. The Mosquito allowed us to reduce consumable use significantly. We currently work in 96-well format and were able to reduce the volumes by a factor 5 to 10, depending on the protocol, the batch size and the plates used. SPT Labtech's technical support is very responsive and helped us efficiently to set up protocols that were not readily available. Compared to other liquid handlers we have in the lab, the Mosquito requires more hands on time as it is not intergrated with shakers, PCR machines and the like in our setup. Additional equipment could fill this gap but require further investments and space. Given the amount we save in term of consumables, the higher cost for technicians per samples is well compensated.
Review Date: 8 Apr 2025 | SPT Labtech
Save your hands and your sanity, use the mosquito!
Genomics
The mosquito is wonderful, very easy to use once it is set up and calibrated correctly. I've been using it to dispense small volumes into 384 well plates - so happy not to do it by hand!
Review Date: 26 Mar 2021 | SPT Labtech
Enabling miniaturized molecular biology with our multi-talented liquid handler. mosquito® HV (High Volume) genomics offers highly accurate and precise multi-channel pipetting from 500 nL to 5 µL, leading to significant savings on precious reagents and time.
User friendly and flexible; low volume pipetting at your fingertips
mosquito® HV genomics provides you with highly accurate and precise low volume pipetting, picking up where traditional liquid handling falls down. mosquito can handle even highly viscous samples (e.g. genomic DNA or enzymes in 50% glycerol), operates with standard microwell plates and can be easily programmed to run a wide range of protocols, which makes mosquito an extremely versatile tool for any genomics lab.
Genomics the mosquito way; miniaturize to maximize
mosquito is changing the way genomics is done - the ability to accurately set up reactions at a fraction of the traditional volumes (often one tenth or less) leads to a step-change in productivity. NGS library preparation, magnetic bead cleanup, cDNA synthesis, whole genome amplification, PCR and qPCR all have been successfully automated and miniaturized with mosquito. Miniaturization leads to large cost savings and allows researchers to maximize their output of results for a given budget.
Automated liquid handling miniaturization for genomics applications
Genomics research has come a long way in recent years, supported by ever-evolving technologies which aim to mitigate on-going challenges such as increased R&D costs, achieving greater throughput, and the need for reproducible and reliable experimental results.
Miniaturization has been a major step forward in tackling issues with laborious manual sample preparation and is particularly feasible for next-generation sequencing library preparation due to the sensitivity and precision of the enzymes involved.
In this SelectScience guide, discover how SPT Labtech’s automated platforms are revolutionizing liquid handling and providing consistency across multiple users within the same facility, or even across different sites.
Download this SelectScience guide to learn about:
- Key automation & miniaturization considerations
- Miniaturization & automation of NGS library prep
- Miniaturized library prep for high-throughput screening
- Accurate, miniaturized DNA quantification assays
- Low-volume, single-cell RNA-seq library prep
- Proven miniaturization of NGS methods
Resource details:
- Document type: SelectScience guide
- Page count: 31
- Read time: 47 mins
- Edition: 2nd
An introduction to miniaturization and automation of NGS library preparation workflows
In this application note, SPT Labtech provides an introduction to miniaturization and automation of next-generation sequencing (NGS) library preparation workflows. NGS has revolutionized the biological and medical sciences, offering superior throughput and greater affordability. Although there has been a considerable drop in the cost of whole-genome sequencing, and the time required, the fundamentals of NGS library preparation remain largely unchanged.
NGS workflows require precise and accurate liquid handling to support both high-throughput demands and sample preservation. Download this application note to learn how to automate and miniaturize NGS workflows, using dynamic, low-volume liquid handling solutions to ensure optimal sequencing depth and coverage for any application.
Miniaturize NGS methods with automated liquid handler duo
Discover how genomics researchers can miniaturize NGS methods to increase throughput and lower costs using the combination of the mosquito® and dragonfly® automated liquid handlers from SPT Labtech in this interview with Field Application Scientist, Chris Waddling. Hear how the combination of mosquito's highly accurate positive displacement pipetting with dragonfly's non-contact, nanoliter-to-milliliter dispensing provides a solution for laboratories looking to scaleup throughput, and learn about the benefits of these instruments in the field of genomics and beyond.
This video was filmed at SLAS2023, San Diego.
The "dynamic duo" of liquid handling: The power of mosquito and dragonfly instrumentation
In this video, Paul Lomax and Donald Ogg from SPT Labtech discuss the dragonfly liquid handling and mosquito reagent dispensing platforms and share how they can be seamlessly used in combination to increase throughput and flexibility of workflows, whilst reducing costs.
This video was filmed at SLAS Europe 2022
SPT Labtech's dragonfly discovery automates Design of Experiments (DOE) to create robust, high-throughput methodology
In this video, Shama Chilakwad, an EngD candidate at Synthace Ltd., describes how SPT Labtech's dragonfly discovery automated the execution of an experiment that used a Design of Experiments (DOE) framework. The dragonfly dispensed fluid rapidly and was able to generate large datasets efficiently.
This interview was filmed at SLAS2020 - watch other highlights from the show here >>
Combination of scRNA-seq strategies to untangle complex cell populations
In this workshop recorded at EMBO Single Cell Biology 2019, Dr. Emilio Yanguez Lopez-Cano from the Functional Genomics Center Zurich discusses the single cell sequencing strategies deployed at his core facility. He explains how they select and combine different single cell RNA-seq approaches, adapting them to the requirements of the research project and the complexity of the samples.
Dr. Klaus Hentrich provides an introduction to SPT Labtech's (formerley TTP Labtech) liquid handling instruments and their applications in single cell genomics.
High-Throughput Microbiome Characterization
In this video, Mike Humphrys, project manager at the University of Maryland's Microbiome Service Laboratory, describes a novel automated workflow for 16S rRNA sequencing using the mosquito HV genomics liquid handling platform from SPT Labtech. This method demonstrates dramatically reduced hands-on time and reagent consumption with miniaturized reaction volumes.
How GeneCore at EMBL combines automation with human expertise
Miniaturization and automated liquid handling transform NGS workflows for precious sample processing
London’s Natural History Museum transforms molecular research
Discover how experts at the London Natural History Museum are advancing molecular biology through cutting-edge automation and robotics
Cellular decision making in normal and leukemic blood stem cells
This guest editorial explores how advances in single-cell technologies to reveal novel insights into hematopoietic development
Taking single-cell RNA-seq by STORM
Join us on Thursday, September 10, to learn how the Mosquito HV liquid handler can help in obtaining single-cell RNA data
Trending in microbiome: From comprehensive culture workflows, to novel biotherapeutics, and microbial characterization
Discover the latest technologies and techniques that are revolutionizing microbiome research
