Lumos Optical Stimulation System by Axion BioSystems
Status:
Reviewer
Member since: 2022
Organization: Baylor College of Medicine Room 506C
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- Ease of use
- After sales service
- Value for money
High quality product. Good value for money.
Application Area: Molecular biology
"High quality product. Good value for money."
Review date: 31 Mar 2022 | Lumos Optical Stimulation System
Status:
Reviewer Member since: 2020
Organization: Shirley Ryan AbilityLab
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- Ease of use
- After sales service
- Value for money
Easy to use, great support.
Application Area:Optogenetic stimulation of HiPSC derived neural spheres
"The Lumos is a powerful system that is easy to use. The software is intuitive. The support team is very responsive to any questions I have about using the device."
Review date: 07 Jan 2020 | Lumos Optical Stimulation System
Status:
Reviewer Member since: 2019
Organization: Northwestern University
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- Ease of use
- After sales service
- Value for money
Good software, reliable device, happy with results.
Application Area:Optogenetically stimulate dissociated DRG neurons
"The Axion software made the Lumos incredibly easy to use. Additionally, the Axion team was incredibly responsive to any questions we had regarding the device and how to use it. For us, it was one of those few pieces of lab equipment we could plug in, turn on, and use with very little fuss. We paired it with Axion's OptiClear plates for imaging of our neurons post-light stimulation. "
Review date: 20 Dec 2019 | Lumos Optical Stimulation System
Status:
Reviewer Member since: 2019
Organization: Georgia Institute of Technology
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- Ease of use
- After sales service
- Value for money
Simple to control high-intensity light patterns without cross-talk between wells
Application Area:Optogenetic stimulation of iPSC-derived neural cultures
"Lumos is a snap to start working with right off the bat. The software makes it really easy to start controlling different lights with different colors and pulse patterns within a couple minutes. By hooking up a light meter under the plate to an oscilloscope, I could see that the light is controlled very precisely (microsecond precision) with really high max intensity reaching the bottom of the well. Perhaps the best thing for me was that the plate/lid design prevents light targeted to one well from bleeding over or reaching adjacent wells, which is pretty important for experiments."
Review date: 19 Dec 2019 | Lumos Optical Stimulation System
Incorporate cutting-edge optical techniques into your in vitro research using Axion BioSystems’ Lumos. Previous in vitro optical stimulation devices provided low throughputs or limited control of light delivery, hindering the adoption of optogenetic techniques in research and development. Lumos is one of the first commercial multiwell optical stimulation systems to offer precise control over intensity and duration to up to four stimulation wavelengths in each of a multiwell plate. Designed to pair with the Maestro Pro and Edge MEA platforms, the Lumos allows researchers to simultaneously direct and record functional network activity.
The Lumos optical stimulation system is available in 3 formats:
- Lumos 24 – four wavelengths per well in a 24-well plate format (i.e. total 96 LEDS): Blue (475 nm); Green (530 nm); Orange (612 nm); Crimson (655 nm)
- Lumos 48 – four wavelengths per well in a 48-well plate format (i.e. total 192 LEDS): Blue (475 nm); Green (530 nm); Orange (612 nm); Crimson (655 nm)
- Lumos 96 – two wavelengths per well in a 96-well plate format (i.e. total 192 LEDS): Blue (475 nm); Green (530 nm)
SYSTEM FEATURES
- HIGH-THROUGHPUT - Simultaneous control of light delivery to each well of a standard SLAS-compliant 24-, 48-, or 96-well microplate
- FULLY CONFIGURABLE - Powerful onboard electronics, enable each of the 96 (Lumos 24) or 192 LEDs (Lumos 48 and Lumos 96) to be independently controlled with finely graded output intensities that are dynamically adjustable on a microsecond timescale
- COMPLETE WAVELENGTH COVERAGE - Four wavelengths per well span the visible spectrum for selective stimulation of all the most-commonly used opsins
- ENVIRONMENTAL CONTROL COMPATIBILITY - Options for the regulation of temperature, CO₂, and humidity enable extended benchtop experimentation
- USER FRIENDLY SOFTWARE - Intuitive “drag-and-drop” style blocks enable quick and easy design of light delivery patterns and selection of target wells
- TOPSIDE LIGHT DELIVERY - Delivery of light from above each well enables even light distribution and leaves the bottom of the microplate open for simultaneous electrophysiology, imaging, or other interfacing modalities
- INDUSTRY-LEADING LIGHT INTENSITIES - Large dynamic range with minimal cross-talk between wells
- PAIRS WITH THE MAESTRO MEA SYSTEM - Seamless integration with the Maestro Pro and Edge MEA systems for optical control of cell activity during real-time recordings of functional responses
Product Overview
