Locked Nucleic Acid probes by LGC Biosearch Technologies

Manufacturer LGC Biosearch Technologies  |  Available Worldwide
Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos). LNAs are modified RNA bases in which the ribose is “locked” with a methylene bridge, connecting the 2' oxygen atom to the 4' carbon atom, fixing it in the C3'-endo conformation.  


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Locked Nucleic Acid probes
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LNAs enable a shorter probe, which supports assay design for:

  • Improved assay sensitivity
  • Higher quenching efficiency (lower background)
  • Greater signal-to-noise ratio
  • Increased hybrization specificity
  • Targeting A-T rich sequences
  • Better mismatch discrimination in SNP genotyping assays
     

Product Overview

Locked Nucleic Acid probes by LGC Biosearch Technologies product image

Locked Nucleic Acid probes

Manufacturer LGC Biosearch Technologies  |  Available Worldwide

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