Invitrogen™ TrueGuide™ Synthetic Guide RNAs
Ready-to-transfect CRISPR sgRNAs designed and validated to provide specific and high-efficiency knockout of your target gene

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Invitrogen TrueGuide Synthetic gRNAs are ready-to-transfect synthetic gRNAs designed and validated to work with the Invitrogen suite of genome editing tools to provide consistent high efficiency editing. Invitrogen is utilizing Synthego's high performance oligo manufacturing to bring you TrueGuide Synthetic gRNAs. Whether you need an economical solution for routine editing tasks or you want to drive maximum editing efficiency, particularly in primary or stem cells, TrueGuide Synthetic gRNAs offer the reagents you require to introduce your specific edit in your cell line.
Key considerations in genome editing
CRISPR gene editing has emerged as one of humanity’s most powerful technologies. Less expensive and relatively easy to design and use compared with older technologies such as zinc finger nucleases, CRISPR-Cas9 approaches are transforming biomedical science. Used initially as a tool to study gene function, the next generation of CRISPR-Cas9 tools are now allowing researchers to target almost any gene for modification in a highly specific and reliable way.
In this eBook, we take a look at the innovative suite of CRISPR-based editing tools from Thermo Fisher Scientific, how those tools can support both basic and applied research applications, and how these tools can be used to improve fidelity and efficiency along every stage of a gene editing workflow – from guide RNA (gRNA) design to cell transfection and characterization of successful edits.
Download for expert advice including how to:
- Design your genome editing experiments with ease
- Achieve high editing efficiency
- Leverage CRISPR for target identification
- Seamlessly translate your research from bench to clinic
Design your CRISPR gene editing experiments in as little as five minutes
Discover how the suite of gene editing technologies from Thermo Fisher Scientific is simplifying gRNA and experimental design












