Fluidity One-W by Fluidic Analytics

Manufacturer Fluidic Analytics  |   Model: 1003-90001
4.7
/
5.0
  |  1 reviews
Assess on-target protein interactions even in crude biological backgrounds.


Fluidity One-W by Fluidic Analytics product image
Fluidity One-W for protein interactions.
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Average Rating: 4.7
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: University of Cambridge



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
The machine is great for investigating the behaviour of proteins in complex solutions.
Rating: 4.7

  • Application Area: Protein binding studies, protein characterisation, molecular sizing

"The Fluidity One-W is an easy to use machine. Pipetting 5 ul of sample on a microfluidic chip is the only thing to do. The advantage of being able to use labelled proteins is that it allows sizing of target proteins in complex solutions and therefore asses binding between proteins. I was able to measure a binding curve in solution within a day. Furthermore, the machine is able to measure low nanomolar concentrations of labelled protein. Currently, the only drawback is the upper limit of the measurable hydrodynamic radius of 20 nm. The service is great and immediate help was promoted in case of malfunctioning."

Review date: 20 Oct 2019 | Fluidity One-W

The Fluidity One-W’s unique capabilities allow you to study protein complexes and their formation in crude biological backgrounds such as lysates or blood plasma. 

Critically measurement of protein size by Fluidity One-W helps determine the identity of your complex and means you can control for off target binding and false positive measurements.

Binding is identified by simple size change from free to bound species — because there is no surface attachment this means you can study proteins in near native conditions. Binding affinity (KD) and stoichiometry of binding are quickly and easily determined.

All measurements are performed fully in solution, with no immobilization to a surface. The award winning microfluidic diffusional sizing (MDS) technology allows highly sensitive analysis, even at low concentrations.
 

Product Overview

Fluidity One-W by Fluidic Analytics product image

Fluidity One-W

Manufacturer Fluidic Analytics

4.7 / 5.0 | 1 reviews