Direct-zol™ RNA Miniprep Plus by Zymo Research

Manufacturer Zymo Research  |   Model: R2070
4.8
/
5.0
  |  272 reviews
The Direct-zol™ RNA Kits provide a streamlined method for the purification of up to 100 ug (per prep) of high-quality RNA directly from samples in TRI Reagent® or similar. Spin column procedure bypasses phase separation and precipitation procedures, for non-biased recovery of miRNA.
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Direct-zol™ RNA Miniprep Plus by Zymo Research product image
Direct-zol RNA Miniprep Plus Kit

The supplier does not provide quotations for this particular product through SelectScience. You can search for similar products in our product directory.




Average Rating: 4.8
272 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Advanced Reviewer
  • Member since: 2021

  • Organization: Texas A&M University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results
Rating: 5.0

  • Application Area: RNA extraction

"The quality of RNA was good for sequencing."

Review date: 05 Jun 2023 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Boston Children's Hospital



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Sold me on the ease of use and time saving
Rating: 4.7

  • Application Area:Isolate RNA from human cell lines

"I like the straightforward protocol direct from Trizol to column. Definitely faster than competitors (not quite 7 minutes though!). Clean high quality results, easiest for cell lines, primary cells gets trickier."

Review date: 27 Mar 2023 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2023

  • Organization: Guillermo Almenara Irigoyen National Hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Useful and effective for different type of samples.
Rating: 4.7

  • Application Area:RNA extraction from blood for RNA expression analysis.

"Easy to use with a high yield of product. It includes a useful DNase step to get a RNA sample ready to downstream process like RT-PCR."

Review date: 25 Mar 2023 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2023

  • Organization: Jordan University of science and technology



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Nice kit for viral detection
Rating: 4.7

  • Application Area:Viral RNA extraction from ear notch samples

"Very nice kit with great RNA yield and purity."

Review date: 10 Feb 2023 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2023

  • Organization: Los Angeles Biomedical center at Harbor UCLA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product and great outcomes. simple and easy to carry out. Highly recommended
Rating: 5.0

  • Application Area:high quality RNA was purified from the primary cells.

"Total RNA, including small RNAs, is effectively isolated from the cells and tissues. The eluted RNA is of high quality and suitable for further molecular and gene expression assays."

Review date: 08 Feb 2023 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Ben Gurion University



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Decent product
Rating: 4.0

  • Application Area:Molecular biology

"Easy to use with decent quality and quantity."

Review date: 10 Dec 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Clemson University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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High-quality product.
Rating: 5.0

  • Application Area:Total RNA extraction for qPCR

"This kit offers the cheapest price for total RNA extraction per unit. The quality of extracted total RNA is high based on spectrometric and electrophoretic analysis. The total extraction time can be done in 30-35 min including 15 minutes of DNAase digestion."

Review date: 06 Dec 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Expert Reviewer

  • Member since: 2016

  • Organization: University of North Carolina at Charlotte



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great, and Accessible RNA Extraction Kit
Rating: 4.3

  • Application Area:A solution kit for best results

"This is an excellent kit for RNA extraction. It provides great quality, and quantity to get the hardest molecule i.e. RNA, which can degrades very easily with the extraction using other kits. However, the zymo plus kit provides an easy and accessible solution and helped me in my research till a great extent."

Review date: 06 Dec 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Miami University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great RNA isolation product and very easy to use
Rating: 4.7

  • Application Area:To isolate total RNA from mouse tissue samples

"I typically get good-quality RNA and good yield too. RNA works very fine for all my downstream experiments."

Review date: 23 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2016

  • Organization: University of Michigan



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and efficiency is high, easy to use and RNA can be used multiple times
Rating: 5.0

  • Application Area:Ion channels analysis

"Great results and efficiency is high, easy to use and RNA can be used multiple experiments"

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus


  • Status:

    Reviewer

  • Member since: 2022

  • Organization: The College of St. Scholastica



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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I highly recommend it if you are working with undergraduate students.
Rating: 5.0

  • Application Area:Messenger RNA expression study using qPCR

"My research lab is mainly for undergraduates. We used to isolate RNA by using the phase separation technique. It was time-consuming, and my students often had to stop in the middle of the procedure. We also had issues with RNA quality associated with inconsistent pipetting of the aqueous phase. After a small accident during one RNA isolation, we made a switch. My students have been happier with the switch because of the reduced time needed for RNA isolation and fewer steps involved in the procedure. The quality of isolated RNA also improved significantly. The kit has saved time and money."

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Harvard Medical School



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great purity RNA!
Rating: 5.0

  • Application Area:Extract and purify RNA from C. elegans.

"Using the Direct-zol RNA mini-prep plus kit, I was able to yield good quality and high concentrations of RNA from C. elegans lysates, allowing me to send for RNA-seq."

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Tabor College



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, easy to use, will continue to use it as my go-to RNA-isolation method.
Rating: 5.0

  • Application Area:RT-qPCR of immune cells in the context of Cancer

"I have been using Zymo's Direct-zol kit for 6 years now and absolutely love it. The price to value is unbeatable. As a graduate student, my PI made us compare results to the standard chloroform spin-down method for both purity and cost. There was nearly no comparison. If you care about purity, saving time, and simplicity, there isn't another option I would recommend."

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: GMU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great reagent and easy to use
Rating: 5.0

  • Application Area:Analyze gene expression

"The reagent is cost effective and easy to use. Purified RNAs are of great quality and reasonable quantity."

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Florida



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product, cannot live without it
Rating: 5.0

  • Application Area:Analyse gene expression in liver samples

"My lab has been using this product for many years. It is easy to use, robust, and with a high yield. More importantly, it also captures small RNA, so we can quantify both protein-coding RNA and miRNAs in the same sample. After beginning using this product about 10 ago, we had never used other similar kits, nor will switch to other kits in the future."

Review date: 21 Nov 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Texas A&M University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Consistent results, good price!
Rating: 4.7

  • Application Area:Extract RNA from mice tissues

"After some optimization, the kit worked well with consistent results. The Support team was amazing."

Review date: 23 Sep 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Rutgers University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great yield.
Rating: 5.0

  • Application Area:RNA extraction

"Great yield."

Review date: 08 Jul 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: University of Minnesota



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It's great!
Rating: 5.0

  • Application Area:Tissue processing and RNA extractions

"The RNA yield was good!"

Review date: 08 Jul 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UC Riverside



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great, consistent product that works better than alternative methods.
Rating: 5.0

  • Application Area:Molecular biology

"Very clean RNA with consistent results. Protocol is easy to follow with good support from the company. The DNase in column treatment works well and saves time downstream. "

Review date: 07 Jul 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UC Riverside



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good kit that is straightforward and gives consistent results
Rating: 5.0

  • Application Area:Molecular Biology

"Kit is easier and quicker to use than alternatives with more consistent results. It is also considerably more affordable than other comparable kits."

Review date: 07 Jul 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UH Manoa



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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nice product with a good price.
Rating: 5.0

  • Application Area:RNA extraction

"The RNA miniprep kit is very easy to use and I got excellent yield and quality of RNAs. Very happy with the kit."

Review date: 09 Jun 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: University of California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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A perfect and reliable way to isolate high-quality RNA
Rating: 5.0

  • Application Area:RNA isolation from tissue

"This is a very easy to use kit for RNA isolation from tissue and cells. A straight forward protocol makes it easy to process multiple samples in a small amount of time. The RNA is of high quality and the data are reproducible and reliable."

Review date: 09 Jun 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Duke University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Satisfied with the results
Rating: 5.0

  • Application Area:Whole RNA extraction from variety of tissues and cells

"Very easy and straight forward protocol. Yield good quantify and high quality of RNA. Good value for the price compare to some other RNA extraction kits."

Review date: 09 Jun 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Northern Illinois University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great product at a moderate price
Rating: 4.7

  • Application Area:DNA isolation

"Achieved high quality yield of DNA. Easy to follow protocol and user's friendly. The price is also cheap"

Review date: 09 Jun 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Federal University of São Paulo



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fast and easy RNA with no contaminants
Rating: 5.0

  • Application Area:Fungal RNA extraction

"My samples are very challenging to lyse pathogenic yeasts. I was used to work with phenol but often had contamination due to our in house protocol. This kit optimized my workflow from 2 days to 20 min experiment"

Review date: 24 May 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: ASU



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great yields, good value!
Rating: 4.3

  • Application Area:Analyzing metabolites in human cells

"This kit provides high yields for an affordable value. Moreover, what I like about all Zymo kits is that you can order just one of the components if it runs low, while in most others you have to buy a new kit!"

Review date: 20 May 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Rutgers University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great results
Rating: 4.7

  • Application Area:RNA extraction for ribosome profiling

"We use Zymo RNA extraction kit to extract RNA from monosome fractions. The quality of the RNA using the kit is excellent, which is so important for downstream library preparation. The kit is also easy to use."

Review date: 20 May 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Bali International University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Can not do research without this
Rating: 5.0

  • Application Area:Research biology molecular

"That product is effective in my research, for sequencing DNA or proteins, analyses of DNA, very easy to use, good quality and stable."

Review date: 01 Apr 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: univerisity



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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It is good
Rating: 3.7

  • Application Area:Tissue samples

"It's an easy of use product, good balance between value and money"

Review date: 31 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: UNAM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good results in short time
Rating: 5.0

  • Application Area:Analyze gene expression

"Easy to use, with great results."

Review date: 30 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: ESALQ/USP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product!
Rating: 5.0

  • Application Area:RNA extraction from tissue

"The kit is easy to be used, the final product (RNA) quality was excelent."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Northern Arizona University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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By far the easiest method I've used.
Rating: 4.3

  • Application Area:RNA isolation from embryos

"DirectZol is super easy to use and I routinely get excellent quality total RNA (e.g., RINs 9-10)."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: National Institute on Aging, NIH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Highest quality reagent for RNA isolation
Rating: 5.0

  • Application Area:RNA isolation from small cell numbers

"Compared to other RNA isolation kits, the Direct-zol RNA Miniprep plus maximizes the amount of RNA isolated from a small sample size. The ability to go directly from TRI Reagent/trizol along with the on-column DNA digestion step reduces sample handling to minimize RNA loss. The RNA is of high quality allowing for several different downstream uses."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: National Institute on Aging, NIH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Highest quality reagent for RNA isolation
Rating: 5.0

  • Application Area:RNA isolation from small cell number

"Compared to other RNA isolation kits, the Direct-zol RNA miniprep plus maximizes the amount of RNA isolated from a small sample size. The ability to go directly from TRI Reagent/trizol along with the on-column DNA digestion step reduces sample handling to minimize RNA loss. The RNA is of high quality allowing for several different downstream uses."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UConn Health



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent kit for excellent results
Rating: 5.0

  • Application Area:RNA extraction from cells and mouse tissues

"I love Zymo products and I cannot wait to open my own lab someday and use exclusively Zymo reagents. I have never had issues with their products and this RNA miniprep kit works wonders for Trizol reactions. It is very dynamic and have gotten me great yields for many papers so far."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Delaware State University



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Good results, compared with competitors.
Rating: 4.3

  • Application Area:Plant viruses

"This kit produces high quality RNA, which can be concentrated using a small volume of elution buffer; no need concentrating afterwards."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Miami University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great cost effective and fast kit
Rating: 5.0

  • Application Area:Transcriptomics

"I used the Direct Zol RNA miniprep kit to isolate total RNA from my bacterial cultures. I was able to receive a high yield with no problem and the kit only takes 20 -30 minutes in total to finish up the whole process. We have purchased this kit multiple times and I highly recommend it as well."

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Johns Hopkins University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great results! easy to use
Rating: 4.3

  • Application Area:Analyze gene expression in cell lines

"Great results! Easy to use, very reproducible"

Review date: 29 Mar 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: NIOF



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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I highly recommend it
Rating: 4.7

  • Application Area:Extracting DNA for PCR applications

"Easy to use, it gives high quality DNA yield, it can be used for PCR applications, it gives reliable results. Good efficiency in time and money saving."

Review date: 01 Feb 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UCI-Medical Center



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Easy protocol and good yield results.
Rating: 4.3

  • Application Area:Extract RNA for further analysis from tissues and cells.

"It has better quality and yields RNA. The protocol is easy and simple and the result is consistent among samples."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: GWU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It worked!
Rating: 5.0

  • Application Area:QRT PCR

"They came on time. Got good quality and yield of RNA. Would highly recommend."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Plant Sciences Inc.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great RNA extraction kit ever
Rating: 5.0

  • Application Area:RNA extraction from plant tissue

"I used Direct-zol RNA Miniprep Plus to extract RNA from plant samples. It ended up in high quality and quantity."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UMW



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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This kit was comparable to others I've used
Rating: 4.3

  • Application Area:Analysis of brain tissue

"The kit worked well and was easy to use. I analyze brain tissue (hippocampus and amygdala) and needed to wash multiple times to eliminate fat. Otherwise was able to use standard protocol that came with kit."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Genome Explorations



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fantastic Products.
Rating: 5.0

  • Application Area:Extraction of RNA for Next Gen Sequincing

"Zymo Research products are by far the easiest kits to use and are extremely effective without and surprises."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Umass Amherst



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product. Time saving. Labor saving!
Rating: 5.0

  • Application Area:RNA extraction for gene expression

"I really appreciate your products which saved a lot of time for me. As a graduate student and a mother of two kids, time is everything. I love your products. By the way, separated purchase available is very consumer friendly. Like the choice a lot."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Narayan Lab @NIH/NIDDK



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Time-saving alterative to traditional RNA isolation.
Rating: 4.7

  • Application Area:RNA isolation from iPSC-derived brain cell types for for qPCR and RNA-seq analysis and validation

"The Zymo RNA MiniPlus kit is very user-friendly. It achieves RNA isolation through a column-based approach. The benefit is a time-saving prep that yields high-quality RNA as analysis by NanoDrop spectra. The one limitation is the column lowers the total RNA yield. Flushing of the column helps to recapture total RNA. This is a great alternative to traditional Trizol and phenol: chloroform isolation protocols which require special waste procedures for both phenol-containing liquid and plastic waste."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Altay Therapeutics Inc



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fast workflow and good quality RNA! Recommend!
Rating: 4.7

  • Application Area:RNA extraction from cells

"This kit is quite easy to use. The RNA quality is very good. The workflow is very easy and quick. The only thing about it that is a little frustrating is that the tubes a slippery and not so easy to handle. They dont have good grip. You have to be very careful or they'll slip out of your fingers."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: CIRB - Collège de France



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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The kit was very easy to use, very fast and provided good results
Rating: 4.7

  • Application Area:Analyse gene expression in human (post-mortem) brain tissue

"Direct-zol RNA Miniprep Plus Kits are great! I'm very satisfied with the efficiency/quickness of RNA extraction from human brain samples, especially when we need high quality RNA for quantification and sequencing. This product is extremely easy to use and provided a good purity of the extracted RNA. And finally, the technical support were very helpful and very responsive."

Review date: 31 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: ASDRP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Awesome!
Rating: 5.0

  • Application Area:Extract bacterial RNA for analysis

"The instructions were easy to follow and I got a good and pure yield for the PCR experiment I needed to conduct using the RNA."

Review date: 27 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: University of Pittsburgh



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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The kit was very easy to use and provided good results.
Rating: 4.0

  • Application Area:Sequence RNA

"The TRI-reagent should always be handled inside of a fume-hood. If you are planning to work with more than 20 samples, a second kit is necessary to have enough of the flow through columns."

Review date: 26 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: University of Nevada, Las Vegas



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, will stick with Zymo for a while.
Rating: 5.0

  • Application Area:RNA isolation for PCR

"This kit is very easy to use and quick to use. I was able to achieve high yield with clean results time after time. I was able to use it for blood, cheek swabs, and saliva. Anytime I called support, they were very helpful and very responsive. I couldn't be happier."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UCR



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, affordable, easy to use!
Rating: 5.0

  • Application Area:RNA extraction for insect samples

"I used this kit to extract RNA from insects and need to detect a RNA virus from it. The kit is very easy to use, save time, and all can be performed under room temperature. I can extract RNA from a singe insect as well as a pool of insects. The chemical reagents within the kit are super enough for extraction uses. This kit is cheaper than Qiagen kit, so it is more affordable. And the extraction result is also very good! BTW, the technical support is very helpful!"

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Georgetown University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good value for money.
Rating: 5.0

  • Application Area:RNA isolation

"Good value for money. Zymo doesn't rip you off, unlike other companies."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Houston Methodist Research Institute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great kit! Use it whenever possible.
Rating: 5.0

  • Application Area:Clean and prepare cytoplasmic RNA for capping analysis.

"This product is extremely easy to use. I love that all of the needed reagents come prepared and aliquoted for continued ease of use. The protocols are easy to follow and provide reproducible results."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Texas Tech University Health Sciences Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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User friendly!
Rating: 5.0

  • Application Area:Analyzing the oncotargets

"The product is quite user friendly. The results were reproducible and high quality. Everyone should know about the great Zymo support team who helps when needed as far as technicalities are concerned. It is a 5/5 for me in all aspects."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Houston Methodist Research Institute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great kit for beginners and very fast.
Rating: 4.7

  • Application Area:RNA Extraction

"The DirectZol kit is great (most of the time). The RNA yields from cell culture are reproducible and the purification process is a "piece of cake." Anyone with novel experience can use this kit and get great results FAST."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: UIC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good product and quality
Rating: 5.0

  • Application Area:Chicago

"If I place order the product today, then I can receive it the next day. After using it, the product is high quality and shows my result. Compare with other vendors, the price is a reasonable. Thank you."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: University of Minnesota



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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The samples were clean and the concentrations were good
Rating: 5.0

  • Application Area:Preparing the samples for qPCR runs

"The samples were clean and the concentrations were good."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Yale School of Medicine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results
Rating: 5.0

  • Application Area:RNA isolation from sorted cells

"I have used this kit for the isolation of RNA from a small number of sorted cells. It worked great, we sent it for RNA-seq and got incredibly good results."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Expert Reviewer

  • Member since: 2016

  • Organization: University of North Carolina at Charlotte



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great Results and Quantity Providing RNA purifying Kit
Rating: 4.3

  • Application Area:To Purify the RNA

"A great kit to increase the quantity and purity of the extracted RNA. I am very happy to use it for my lab samples which needs high quality RNA for quantification and sequencing. Very amazed with the productivity of this kit."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: university of vermont



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Works well to provide pure mRNA at a good price.
Rating: 5.0

  • Application Area:mRNA isolation from whole tissue in Trizol

"Our lab tried this product after years of Trizol/Chloroform extractions. We needed a kit that would produce *clean* mRNA with little Trizol carryover for downstream RNAseq applications. This kit did its job well and produced clean, pure mRNA and is less expensive than RNeasy and RNaqueous counterparts. The Zymo website also provides a brief video of the protocol which we found to be a helpful introduction. Our procedure, briefly: After grinding the tissue in liquid nitrogen and adding Trizol, we passed the mixture through a Qiashredder. After pelleting the debris, the Trizol/lysate supernatant was put through the Direct-Zol kit."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: USUHS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great quality results!
Rating: 5.0

  • Application Area:Analyze transcripts in a tissue sample

"It is easy to use. Great quality end product."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: university of florence, Italy



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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RNA extractions with optimal RIN score, NGS ready
Rating: 5.0

  • Application Area:NGS ready total RNA in minutes

"I had to extract 50 samples for total RNA, these samples had to be sequenced for splice variants. Considering that the number of samples were quite a few, I did opt for the traditional method nor the Qiagen (as the DNAse treatment is a column and not a physcial enzyme). I used the RNAzolkit, and within 15 mins is at least 95% of the samples with RIN of >7. This kit is rather easy to use with the DNAse I digestions step in the column itself, so that was good. The NGS run was great so this one is good especially because you can also store your RNA in TRIZOl and extract the RNA whenever you want without the fear of degradation."

Review date: 25 Jan 2022 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Universidad Juárez del Estado de Durango



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Excellent product I think is the best with regards to cost benefit relation
Rating: 4.7

  • Application Area:Gene expression in tissue samples

"It is really very easy to use, we just had the problem with the sample homogenization, we were working with pancreas tissue and the RNA was easily degraded, but this kit was the option with one we got the best result using a homogenization with trizol in low temperature."

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Texas at San Antonio



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Easy to use
Rating: 3.3

  • Application Area:Analyze RNA

"Product was effective and easy to use. Price is also okay"

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: UNAM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Best tool for RNA isolation it helps to achieve high quality and purity
Rating: 5.0

  • Application Area:Analyze gene expression

"Direct Zol was the best tool for RNA isolation it helps to achieve high quality and purity from my samples also reduces the time consuming compared with the traditional method"

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: University of Cordoba



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results. It´s my favourite method for RNA isolation
Rating: 5.0

  • Application Area:RNA isolation in tissue samples for gene expression analysis

"An excellent method to quickly isolate high-quality RNA directly from samples in Trizol, TRI Reagent or similar from different sample sources (cells, tissues, serum, plasma, etc.)."

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Texas A&M University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fantastic kit! I look forward to using it again.
Rating: 5.0

  • Application Area:Isolation of insect RNA for RNA sequencing and de novo transcriptome assembly

"I used Zymo's Direct-zol RNA miniprep kit for the isolation of RNAs from specific caterpillar tissues for Next Gen Sequencing. Because I was isolating RNAs from multiple different tissues of each individual, I had to process 100s of samples! I was able to rapidly isolate high-quality RNA from the tissues and obtain high yields. This kit really saved the day when it came to processing 100s of tissue without losing any quality of isolated RNA in the sample!"

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: ASDRP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Extremely good at extracting RNA, would definitely recommend!
Rating: 4.7

  • Application Area:RTqPCR/RNA extraction from cancer cells

"The Miniprep Plus was extremely good at extracting RNA in sufficient concentrations. The instructions were also very clear, but I think it would have been beneficial to have more volume of each solution. Other than that, it was great!"

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: University of Ilorin, Nigeria



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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The RNA yield and purity was simply fantastic
Rating: 4.3

  • Application Area:Extraction of RNA for gene expressions studies

"The RNA yield obtained using the kit was great and the purity was ok to perform any throughput analysis."

Review date: 16 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Sao Paulo



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result and easy to use.
Rating: 5.0

  • Application Area:RNA sequencing

"I achieve high quality RNA that is used as an input for RNA sequencing."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Efficient RNA extraction in 0.5 h and good quantity/quality of RNA from small tissue.
Rating: 5.0

  • Application Area:Extract RNA from small tissue like choroid plexus to explore differential gene expression

"The sample kit is a good start for my first trial of RNA prep and it is very useful for me to compare different kit based on my sample size."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Florida



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and very easy to do the assays
Rating: 5.0

  • Application Area:Analysis of mRNA level changes

"The kit is very easy to use, even my undergraduate students can finish the experiments very well and fast, the RNA quality and yield is pretty high. The price of this kit is reasonable."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Virginia Tech



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great RNA quality.
Rating: 5.0

  • Application Area:RNA extraction from mosquito midguts

"The product is very easy to use, in a relatively less amount of time with better RNA quality."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: NYU Grossman medical school



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent value for money
Rating: 5.0

  • Application Area:RNA isolation from primary cells.

"The protocol is straightforward and easy to use. Compared to red/blue it's also relatively cost effective. The yeild concentrations are spectacular!"

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UNC Charlotte



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great Results, with High Efficiency
Rating: 4.0

  • Application Area:Good Kit to Work With

"I like the capacity of the kit. It provides good results and very easy to use. Highly efficient and cost effective. Very happy to have and would recommend for the best RNA procedure."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Uni of Hawaii-JABSOM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results.
Rating: 5.0

  • Application Area:RNA seq

"This item is very useful for the quick extraction of tissue RNA samples with high purity."

Review date: 15 Dec 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: MGH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, easy to use, worked well.
Rating: 5.0

  • Application Area:Extracting RNA from cells in culture

"Anyone who has tried RNA extraction from tissue/cell lines can attest to the frustrations that may be present throughout the process. From low yield to degradation, RNA extraction can be very challenging using any method. This kit was surprisingly easy to use, and gave great results. Will definitely be purchasing the full kit for future use."

Review date: 17 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: ASDRP



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great results! Would definitely recommend!
Rating: 4.3

  • Application Area:Extracting RNA from tissue culture

"This prep kit is easy to use and has all the materials. We were able to isolate the RNA in good concentrations, which we then used for our projects."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Low yield from biofilmy bacterium, good yield from green alga..
Rating: 4.7

  • Application Area:Transcriptomics

"Unfortunately, this kit did not allow me to purify sufficient RNA from a tough-to-lyse bacterium that makes some unknown biofilmy stuff. However, it did result in high yield RNA from the alga chlamydomonas reinhardtii, albeit the quality assessed via bioanalyzer trace was just OK (not perfect)."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: ISU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results generated for NGS.
Rating: 5.0

  • Application Area:RNAseq

"Great kit. Easy to use and reliable results. Perfect for NGS applications."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Louisville



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results!
Rating: 5.0

  • Application Area:RNA extraction and gene expression

"Very easy to extract RNA, simple fast and good concentrations."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: SDSMT



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great results. We use this kit very often in our lab now
Rating: 4.3

  • Application Area:RNA extraction from thermophiles

"The Direct-zol kit is very useful for extracting DNA from bacteria, and it worked just so well for our thermophilic cultures. The results and yields were reproducible too, and the transcriptomic data that was processed using the RNA extracted from RNA zol was of high quality."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: mayo clinic



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product and guarantee to get what you want.
Rating: 5.0

  • Application Area:Gene expression

"Using this kit to obtain RNA is easy and very effective. You can get higher yield and purer RNA. The RNA obtained is great for downstream application, such as RT-PCR, RNA sequencing, and gene cloning. Customer service is great too, very informative and helpful."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Kansas State Unvieristy



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product for RNA extraction.
Rating: 5.0

  • Application Area:RNA extraction for wheat plants

"Rapid and reliable isolation of RNA for qRT-PCR analysis in plants."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Perelman School of Medicine at the University of Pennsylvania



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Works with frozen samples
Rating: 5.0

  • Application Area:Neuroscience

"We had existing samples that were frozen in tri-reagent and these kits worked well for extracting high quality RNA."

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: GMU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result.
Rating: 5.0

  • Application Area:Purify RNA from suspension cells

"This product is very easy to use. The protocol is simple to follow. I got great RNA quality and quantity. The qRT-PCR Results from the RNA were very clean"

Review date: 16 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: University of Penn



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent results.
Rating: 5.0

  • Application Area:RNA Purification

"Excellent to purify RNA in an easy and fast way with high quality and quantity RNA."

Review date: 15 Nov 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: The Ohio State University



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Excellent products for consistent results!
Rating: 4.3

  • Application Area:Analysing recombinant RNA molecules

"The kit has been working very well with consistent results with good RNA quality and yield. The spun columns are handy compared to the Trizol method. The procedure is straightforward to follow as well."

Review date: 07 Sep 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Instituto de Investigação e Inovação em Saúde (i3S)



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great. Easy and efficient kit.
Rating: 5.0

  • Application Area:Adipose tissue

"Very interesting, feasible, and highly efficient method for RNA extraction from adipose tissue."

Review date: 21 Aug 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Virginia



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Quick and easy isolation of high quality RNA.
Rating: 5.0

  • Application Area:RNA isolation from murine cell lines and tissues for RT-qPCR and RNA-seq

"RNA quality is very good and the kit is very easy to use, which makes the whole procedure more reproducible even in unexperienced hands. You can quickly get high quality RNA without worries of losing your RNA pellet."

Review date: 01 Aug 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Marine Biological Laboratory



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Simple and robust kit with great price.
Rating: 4.3

  • Application Area:Transcriptomics

"Direct Zol is a simple and robust kit to get your RNA out of cells. You may better off with your turboDNAse treatment, althugh kit has its own DNAse in it and recomended to use following the protocol."

Review date: 29 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Minnesota



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great results.
Rating: 4.0

  • Application Area:Gene expression

"This kit is easy to use and we can get enough amount of RNA for RT-qPCR from mouse skeletal muscle tissues and cultured cells. The protocol is simple and we do not need any special equipment for this kit. The price is not as expensive as other similar kits."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: ASDRP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very easy to use and worth the money!
Rating: 5.0

  • Application Area:Extracting RNA

"This kit was very useful to extract RNA from cancer cells to use for qPCR experiments. The instructions were easy and efficient!"

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Suretox lab



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great yields, minimal time and authenticated downstream application results.
Rating: 5.0

  • Application Area:Using for TaqMan Assays for cytokines

"I have used so far 10 Direct-zol RNA Miniprep Kits to purify RNA from adherent and suspension cell samples lysed in Trizol and always performed the optional on-column DNAse digestion. The yields were extremely good, most samples show RNA yield more than expected over OD 260/280 2.0. I stopped using big brand kits, which take a much longer time to purify with lower yields and this Direct-zol RNA Miniprep Kit seemed like such a convenient alternative."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: ASDRP



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Amazing results for research work.
Rating: 5.0

  • Application Area:Analyze various biological samples

"It is easy to use, reliable, and accurate. Good for beginners as well."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Expert Reviewer

  • Member since: 2020

  • Organization: Montana State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good efficiency and plasmid recovery.
Rating: 5.0

  • Application Area:Gene cloning

"Easy to use, reproducible results, and no special aftercare needed."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Washington University Biology



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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DirectZol is wonderful for RNA isolation and transcription reaction cleanup.
Rating: 5.0

  • Application Area:Direct isolation of RNA from Trizol lysates; isolation of capped mRNA

"I find the Direct Zol RNA isolation kit the fastest, easiest, and highest yielding method for isolation of RNA from Trizol extracted Drosophila tissue lysates. So much easier than centrifugation followed by phase separation. I've also started using the kit to clean up capped mRNA T7 ARCA transcription reactions, and the yields are wonderful! Usually get 600 to 700 ng/microliter of clean useable mRNA for insect transgene injections. I highly recommend this product."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: UNAM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results.
Rating: 5.0

  • Application Area:Analyze gene expression

"Is really easy to use and reduces steps on the traditional method to obtain pure RNA."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Northwestern University-Feinberg School of Medicine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy and simple, High yield and high quality of RNA prep kit.
Rating: 5.0

  • Application Area:Total RNA extraction from live cells after FACS sorting

"We’ve been working to generate pipeline with bulk RNA seq. Our lab tried several kits from different companies, then decided to purchase the entire kit from Zymo after trying a sample kit. This kit gave us highest amount of RNAs with hight quality for RNA-seq from both whole tissue and cells collected from FACS. The columns works perfect with Trizol agent-which is the most common reagent and in-column digestion to remove DNAs was another benefit! Easy to follow the directions and reasonable price for 50 preps, compared to other competitors. Highly recommend."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: The Jackson Laboratory-GM



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Does the job with ease.
Rating: 5.0

  • Application Area:RNA-seq, quant-seq, qPCR

"Direct-zol™ RNA Miniprep Plus is excellent value for money over similar products."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: Universidad de Córdoba



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use. Good yield.
Rating: 4.7

  • Application Area:Isolation of nucleic acids

"It was easy to manipulate, product isolated was good on both yield and quality."

Review date: 28 Jul 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: DermBiont



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good performance.
Rating: 4.3

  • Application Area:RNA extraction for RNAseq

"The RNA yield was better than other products, but the column-based method does not have a high throughput. It would be helpful if the product can be improved for automated pipelines."

Review date: 09 Jun 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Witwatersrand



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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RNA extraction has never been easier.
Rating: 4.7

  • Application Area:RNA extraction

"Gives you great quality RNA in high concentrations every time! It’s very simple and easy to use and instructions are crystal clear. "

Review date: 07 Jun 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: University of Toronto



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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It is good.
Rating: 4.0

  • Application Area:Nucleic acid - protein extraction

"It is easy to use, you can use trial in the beginning. The protocol is short and effective. Technical support is good."

Review date: 26 May 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: UNMC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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New staple in our lab!
Rating: 5.0

  • Application Area:RNA Isolation

"This product is quick and easy to use. Very reliable with clean RNA. We switched from a standard RNA isolation method to this product because of its consistency and reliability of the final product."

Review date: 14 May 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Texas A&M University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Awesome kit, would recommend to other scientists.
Rating: 5.0

  • Application Area:RNAseq

"This is a great and easy kit that reliably gives really high quality and great yield as well. Our lab's go-to for RNAseq projects."

Review date: 18 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Assam University, Silchar, Assam, India



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Fantastic package! Simple to use and extremely dependable in terms of performance.
Rating: 4.3

  • Application Area:Pathway analysis in Yeast Cells

"This is a very simple and fast product for RNA extraction from a variety of yeast cells. Postgraduate and PhD students routinely isolate mRNA from several yeast species. We tested several species from Pichia, Candida, Saccharomyces, and Komagataella. On average we get RIN value of 9 for the isolated RNA which is great for our downstream applications expression analysis. The recovery is good too, with yield ranging from 850-1000 ng/ul RNA. We simply love the on column DNAase digestion, clean up in 45 minutes. Above all, the price per sample fits to our budget. With wide range of distributors we get this product in the remote area in weeks. It fits the bill perfectly."

Review date: 18 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: UTMB



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good results.
Rating: 5.0

  • Application Area:PCR applications

"Efficient, high quality easy to use."

Review date: 17 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Berlin Institute for Medical Systems Biology at MDC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy, fast & reliable.
Rating: 5.0

  • Application Area:RNA extraction from human cell lines

"The product is extremely easy to use and saves time compared to the competition, without compromising the yield and quality of the extracted RNA."

Review date: 17 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Awesome results, very happy with the product!
Rating: 5.0

  • Application Area:RNA isolation

"I have been using this product for a year now and it works very good for RNA isolation from all kinds of samples."

Review date: 17 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: SUNY BINGHAMTON UNIVERSITY



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Student friendly.
Rating: 5.0

  • Application Area:Drosophila studies

"Absolutely easy to use. The students were able to complete the experiment independently and the results were very similar to the results from Qiagen."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Expert Reviewer

  • Member since: 2020

  • Organization: Montana State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use, good results.
Rating: 5.0

  • Application Area:Molecular cloning

"High quality and clean recovery of products, Easy to use, Fast and time saving."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Massachusetts General Hospital/Harvard Medical School



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results. Cannot go back to other similar products!
Rating: 5.0

  • Application Area:Miniprep for vector cloning

"It is easy to use, I especially love that we do not have to pellet the bacteria and resuspend before lysis. The yield and quality is good as well. Worth the money, and you save time and work."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Illinois



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results!
Rating: 5.0

  • Application Area:Analyze mRNA in bovine tissue samples (liver, uterus, uterine smear, rumen pappillae...)

"I found this kit one of the easiest ones to extract RNA from tissue samples and it works very nicely as well with smear samples (from uterine content). The protocol steps are easy to follow and I have always received the product in great condition - I bought it several times already!"

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Greatest.
Rating: 5.0

  • Application Area:Isolate RNA from cells and tissues

"Great product."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Pacific University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Best for the price, but get other DNase.
Rating: 4.3

  • Application Area:RNA expression tracking

"Overall, I think this is a great product. It is easy to use and the steps are pretty clear. You can't beat the price either. My only negative comment is that the DNase doesn't seem to work very well. Our labs ended up buying it from another supplier and just using it with this kit."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Southern California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
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Quick isolation of RNA for sequencing or PCR.
Rating: 4.3

  • Application Area:RNA isolation for sequencing

"The product comes easy to use, with minimal steps after trizol application to 2D tissue culture on plastic or glass. The purity comes out pretty close to what is reported, although it seems less consistent when cell counts are lower. Time of isolation is cut significantly. I think it is worth it if you are willing to pay a premium compared to traditional methods of isolation."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UNAM



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Compared to other kits it is very good.
Rating: 4.3

  • Application Area:Lymphocyte mRNA extraction

"The procedure is clear, easy to carry out, the amount of mRNA was lower than expected and the quality was regular, we are in the standardization phase, I hope that once the points to be corrected have been identified, the performance of the insert can be achieved."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Universidad Autónoma de Yucatán



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent result and easy to use.
Rating: 5.0

  • Application Area:Extraction DNA and RNA

"We purchace Zymo Resesrch because, the data we get is better in comparison with other companies."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Princeton University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good product and saves your time.
Rating: 5.0

  • Application Area:RNA extraction

"This product is really easy to use. Take less time and generate high quality RNA in most of my samples."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Clemson University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Amazing results. Easy to use.
Rating: 5.0

  • Application Area:Extracting RNA from cell culture samples

"This product is 100% effective when used in extracting RNA from cell / tissue samples. The simplicity of the protocol is amazing. It is well detailed and easy to follow. The RNA yield is usually pretty accurate based on my hypothesis. Also, the product content last a long time."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: North dakota state University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results from this kit.
Rating: 5.0

  • Application Area:RNA isolation from cells and tissue

"This kit gives reproducible results all the time I use it and the most important thing is that it is very easy to use just by following the procedure."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Kansas State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Time efficient, great reproducibility.
Rating: 5.0

  • Application Area:Virus detection and human immunology

"I have used exclusively Zymo products for 10 years now in all my RNA and DNA extractions. Great products, increase reproducibility, easy to follow protocols."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: CSS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Takes the worry out of isolating RNA.
Rating: 5.0

  • Application Area:Cleaning and isolating RNA from a variety of samples

"This is my go-to product for the application. It's easy to use, quick and efficient. The protocol is clear enough that students can handle the extraction process too."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Mount Sinai



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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The Zymo kits are easy to use and cheap! The results are awesome.
Rating: 5.0

  • Application Area:Molecular biology - extraction of RNA

"The product is cheap and easygoing. The results are delightful."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Tulane National Primate Research Center



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great kit for isolation of good quality RNA.
Rating: 4.7

  • Application Area:Analyze RNA in samples

"Good quality RNA can be obtained with easy to use kit."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Clemson University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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High purity, and easy protocol.
Rating: 5.0

  • Application Area:Purify the total RNA from eukaryotic cells

"The protocol is easy to use and the produced total RNA is high purity and does not contain genomic DNA, since there is a step for DNase incubation during purification. The yield is comparable to other vendors."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Brown University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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High quantity with good quality of RNA sample.
Rating: 4.7

  • Application Area:RNA isolation from tissue samples

"It worked nicely. I got a lot of RNA with good quality. 260/280 is 2.5."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: COLUMBIA UNIV



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product, highly recommend.
Rating: 5.0

  • Application Area:Extract RNA from tissue sample

"A very good product, has detailed protocol, easy to use and can get good results. Highly recommend."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Yale School of Medicine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results.
Rating: 5.0

  • Application Area:RNA isolation from PBMC

"The product was good and RNA quality was good."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Virginia Tech



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Definitely great results obtained really easily.
Rating: 4.7

  • Application Area:Digestion of mosquito midguts for RNA

"The RNA yields were pretty good, it was easy to use and definitely worth the money."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Johns Hopkins University



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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I obtained reproducible results and it is easy to use.
Rating: 4.0

  • Application Area:Pasmid isolation for KO clones

"I obtained reproducible results and it is easy to use."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Cornell University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Share this ReviewShare this Review on TwitterShare this Review
Great results, good yield!
Rating: 5.0

  • Application Area:RNA seq experiments from samples

"Direct-zol RNA Miniprep Plus kit is the best in the market for RNA extraction. It is easy to use and gives great yield. The best part is that it can also extract small RNAs from samples. I would definitely recommend for use to everyone!"

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UMASS Medical School



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Strongly recommended to isolate RNA from mycobacteria and eukaryotic cells.
Rating: 5.0

  • Application Area:RNA isolation

"Reliable and consistent quality of RNA obtained when using these Zymo kits."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Boston children’s hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Reliable product and wonderful service.
Rating: 5.0

  • Application Area:RNA extraction and qPCR

"It’s a very good and reliable product. We use it to extract RNA from fungal samples, and it’s quite easy to use and compatible with trizol stored samples. The only thing is that we tend to have to do a second round of DNAse digestion to remove trace amount of gDNA contamination. The customer service is very nice and once they even offered to fill up our back ordered kit with free samples (didn’t go for that but really appreciate their kind gesture to do anything possible to care for the customers). RNA quality off the column is always good."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Institut Pasteur Montevideo



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great and esay to use extraction and purification RNA kit.
Rating: 5.0

  • Application Area:Molecular biology

"Really ease to use RNA purification kit directly from phenol/trizol or directly extraction from cell. I use in general from trizol (cells ans tissue). It work really nice, with very good RIN number (>9 in general) generated in bioanlayzer equipment. RNA was used to downstream RNAseq analysis, cDNA generation an RT-qPCR without problems."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Nord University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Perfect RNA extraction kit for the scientist who doesn't like to waste her/his time.
Rating: 5.0

  • Application Area:Total RNA extraction from the different types of animal tissues such as gills, liver, and embryos

"Direct-zol™ RNA Miniprep Plus is a very simple and fast resolution of the RNA extraction issues. RIN values usually higher than 9.0 for the fresh tissues."

Review date: 16 Mar 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Louisville



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product can’t live without it!
Rating: 5.0

  • Application Area:RNA purification

"Zymo's Direct-zol RNA Miniprep Plus is the bomb! It provides the easiest, best, and most economical way for us to isolate RNA from microbial cells (especially fungi). The on-the-column DNase is quicker and easier to use than other kits where the treatment has to be done separately."

Review date: 02 Feb 2021 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: DEPARTMENT OF GENETICS UNIVERSITY OF DELHI SOUTH CAMPUS



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results obtained.
Rating: 5.0

  • Application Area:RNA isolation from animal cells

"Used this product for RNA isolation from animal cells. The quality of isolated RNA was very good in terms of RIN value. Used the isolated RNA for cDNA synthesis, gene-expression microarray and transcriptome sequencing."

Review date: 09 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: nyu



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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This is an easy to use RNA prep kit with good quality.
Rating: 5.0

  • Application Area:System biology

"This is an easy to use RNA prep kit with good quality."

Review date: 08 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Boston Children’s Hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very reliable product and easy to use.
Rating: 5.0

  • Application Area:Define expression level in Candida Albicans

"This is a very good product that was recommended by my colleagues. It is suitable for the extraction of yeast/Candida total RNA from samples stored in Trizol. It is very easy to use, takes around 30-40 total to finish the extraction, on column DNase digestion and the final concentration reading. The recovery is good too, I ususally get 800-1000 ng/ul RNA from the column. One thing to notice that is these columns do have maximum capacity. Since we tend to have slightly higher cell numbers to apply to the column, we have used an additional ‘in the tube’ DNase digestion step to make sure the complete removal of gDNA contamination. We also purchase the columns separately just for regular RNA cleaning procedure. All the qRT results look quite good."

Review date: 05 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: DUKE



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Amazing kit! Easy to use and very reliable to obtain results. Highly recommend it!
Rating: 5.0

  • Application Area:RNA extraction in PBMC and human tissue

"The quality I am looking for in PBMC is usually as high as possible in both ratios 260/280 and 260/230 because these samples are usually sent for sequencing and many of them are nor replaceable. This kit, in addition to be easy to use and to explain to others, ensure high yields and ratios if it is used properly. Highly recommended to use!"

Review date: 04 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: UCLA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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I like this product so much, saving me from RNA extraction.
Rating: 5.0

  • Application Area:RNA extraction from tissue samples

"1. It's easier to use with column filters than regular Trizol extraction of RNA. DNase I included guarantees the quality of RNA without DNA contamination, good for various downstream applications. Also, the small RNA is collected and can be used for more comprehensive RNA profiling. 2. I remember once I contacted the technical support for some questions, I got the reply pretty quick. That makes me more confident in the company's devotion on customers. 3.The price is more competitive compared to other companies, considering the performance and easiness."

Review date: 04 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: Keck of USC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Save time! Save money! Save life!
Rating: 5.0

  • Application Area:Transcriptom in human samples

"The Direct-zol RNA Miniprep Plus Kit is very effective for purifying total RNA from Human cancer cells. The protocol is pretty straightforward and time efficient. The RNA quality is very high. I used the RNA for the total RNA sequencing. The data is great with average read quality higher than 35.50. And the results are very reproducible. I strongly recommend this product."

Review date: 04 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Colorado State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, easy to use, great quality reagents.
Rating: 5.0

  • Application Area:Plant tissue for viral testing

"This product yields amazing results with easy to use instructions. It is a time saver - a big plus for the lab. Very cost effective and highly reproducible. High quality RNA. In my lab, students can follow instructions without having prior experience minimizing errors and repeats. Quality of reagents is superb. I would highly recommended."

Review date: 04 Dec 2020 | Direct-zol™ RNA Miniprep Plus
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: UNC Chapel Hill



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results in less time than using conventional methods.
Rating: 5.0

  • Application Area:RNA isolation

"This kit significantly reduces the time of extraction without compromizing the quality of RNA. The protocol is very easy to follow and it does not require any special reagent preparation. I strongly recommend it for tissue and cells."

Review date: 04 Dec 2020 | Direct-zol™ RNA Miniprep Plus