Member since: 2020
Organization: Institue of Materia Medica Chinese Academy of Medical Science
Speed up your drug discovery process with low cost!
Application Area: Drug Screening
"Dianthus is an effective tool for lead discovery, we use it for small molecular screening. It just need 20 uL samples & 30 mins to screen 384 samples. Meanwhile, the use of multi-well plates can save a lot of money for our lab so it is a quick, simple & cost effective instrument for lead discovery."
Member since: 2006
Organization: Birla Inst of scientific Research
Data quality is amazing.
Application Area:Biomolecular interactions
"Dianthus is a simple, easy instrument to measure binding affinities. Most importantly, it doesn't need any maintenance. NanoTemper support post sales is exceptional."
Dianthus removes the complexity of binding interaction measurements for drug discovery screening. Get the fastest time to meaningful results with no immobilization required, because you demand it.
Explore every target, even the most challenging ones
There’s no end to the projects you can do. Study targets of any size or mass — from ions to multimeric proteins — and type — proteins, nucleic acids, saccharides, and more.
Evaluate any sample type in any buffer
Dianthus isn’t picky. Feel free to prep your target in the buffer that ensures its stability and integrity. Even use lysates or bioliquids without diluting them.
Measure affinities with the highest sensitivity
Whether strong or weak, Dianthus detects a wide range of binding affinities — picomolar to millimolar — so you don’t have to use other methods.
Characterize in solution, no immobilization required
Analyzing interactions in close-to-native conditions is ideal. Dianthus characterizes in solution, so interfering with your target’s binding site or spending on expensive immobilizing chemistries isn’t an issue.
Consume small amounts of target and compounds
Every little bit counts. Saving on costly sample and library compounds means you can do more screening or use them in other projects.
Get meaningful results faster at any throughput
Dianthus swiftly analyzes 384 data points in 30 minutes and has flexible throughput. Choose to run one sample or as many as you want.
With Dianthus, there’s no fluidics. That means regular maintenance is not required which means there’s no downtime which means you can use it 24/7 whenever you want. Since Dianthus uses a 384-well microplate format, it’s compatible with many automation solutions and easily fits into your current workflow for even more hands-free time.