Corning® Supersomes™ P450 Inhibition Kit CYP19/MFC, 1/Case by Corning Life Sciences

Kit Components:• CYP19 + P450 Reductase• Control: Insect Cell Membrane Protein• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized• Stop Solution: 0.5 M Tris Base, filter sterilized• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)• MFC (7-Methoxy-trifluoromethylcoumarin): Fluorescence substrate, 1.21 mg• KTZ (Ketaconazole): CYP19 selective positive control inhibitor, 0.0... Read more


Corning® Supersomes™ P450 Inhibition Kit CYP19/MFC, 1/Case by Corning Life Sciences product image
Corning® Supersomes™ P450 Inhibition Kit CYP19/MFC, 1/Case


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Kit Components:
• CYP19 + P450 Reductase
• Control: Insect Cell Membrane Protein
• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized
• Stop Solution: 0.5 M Tris Base, filter sterilized
• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate
• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)
• MFC (7-Methoxy-trifluoromethylcoumarin): Fluorescence substrate, 1.21 mg
• KTZ (Ketaconazole): CYP19 selective positive control inhibitor, 0.032 mg
• HFC (7-Hydroxytrifluoromethylcoumarin): Metabolite standard (0.25 mM in 0.1 M Tris-pH 9.0)

Note
• Freeze/thaw stability: This CYP19 inhibitor screening kit was subjected to 6 freeze/thaw cycles without a change in IC50 value for ketaconazole or a significant loss of signal to noise
• xx = Actual values can be found on the data sheet accompanying each shipped product

Preparation and Storage
Store at -80°C

Product Overview

Corning® Supersomes™ P450 Inhibition Kit CYP19/MFC, 1/Case by Corning Life Sciences product image

Corning® Supersomes™ P450 Inhibition Kit CYP19/MFC, 1/Case

Manufacturer Corning Life Sciences

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