Anti-GABPA Antibody by Merck KGaA, Darmstadt, Germany

Manufacturer Merck KGaA, Darmstadt, Germany  |  Available Worldwide
4.7
/
5.0
  |  1 reviews
Detect GABPA using this Anti-GABPA Antibody validated for use in Western Blotting and Chromatin Immunoprecipitation (ChIP).


Anti-GABPA Antibody by Merck KGaA, Darmstadt, Germany product image
Anti-GABPA Antibody

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Average Rating: 4.7
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: King's College London



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Works for IP. Less sensitive for Western Blot.
Rating: 4.7

  • Application Area: Immunoprecipiation, Western blot

"It works for IP at the dilution suggested. For Western Blot it's not very powerful. Weak signal, however clean (no background). Needs to be used concentrated (1:250-1:500)."

Review date: 09 Aug 2019 | Anti-GABPA Antibody

GA-binding protein alpha chain (UniProt Q00422; also known as GA repeat binding protein alpha, GABP subunit alpha, GABPalpha, NRF-2, Nuclear respiratory factor-2) is encoded by the Gabpa gene (also known as E4tf1a) in murine species (Gene ID 14390). GABPalpha is a redox-responsive transcription factor that plays an anti-oxidant, pro-survival role in mitochondrial biogenesis process. GABPalpha is upregulated in response to oxidant exposure or increased cellular reactive oxygen species (ROS), where it mediates the transcription of mitochondrial transcription factor A (mtTFA) that is needed for mitochondrial DNA transcription.

Product Overview

Anti-GABPA Antibody by Merck KGaA, Darmstadt, Germany product image

Anti-GABPA Antibody

Manufacturer Merck KGaA, Darmstadt, Germany  |  Available Worldwide

4.7 / 5.0 | 1 reviews