Xpert® GI Panel
The Xpert® GI Panel provides fast, accurate detection of multiple bacterial, viral, and parasitic pathogens with results in about 74 minutes. Its streamlined, <1‑minute hands‑on workflow delivers actionable information to support confident clinical decisions across care settings.
Xpert® GI Panel cartridge
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The Xpert® GI Panel is designed to bring clarity and speed to the diagnosis of infectious gastroenteritis—an illness that remains a leading cause of morbidity, mortality, and healthcare visits¹. Because bacterial, viral, and parasitic pathogens often present with similar symptoms, clinicians can struggle to distinguish between infectious etiologies based on clinical presentation alone¹. Traditional diagnostic methods add further complexity, as they are frequently time‑consuming, costly, and limited in sensitivity². Fast, accurate detection is essential to guide appropriate therapy and support infection control and epidemiologic measures that help reduce or prevent the spread of disease¹.
Built to address these challenges, the Xpert® GI Panel delivers quick, actionable, and accurate results in approximately 74 minutes, helping clinicians make timely decisions that support better patient management. Its standardized, streamlined workflow is clinically tailored to identify common pathogens associated with suspected gastrointestinal infection³⁻⁴, reducing unnecessary testing and medical procedures while enabling earlier, appropriate interventions²⁻⁵. This combination of speed, simplicity, and reliability reflects a practical solution for improving care in settings where rapid clarity matters.
The panel’s targeted, mid‑plex design captures meaningful proportions of clinically relevant pathogens while reducing over‑ or co‑detection of organisms with limited clinical significance⁶. By focusing on the pathogens that matter most, the Xpert® GI Panel supports confident interpretation and minimizes diagnostic ambiguity—helping clinicians act decisively and efficiently when managing suspected infectious gastroenteritis.
References
1. Binnicker MJ. 2015. Multiplex Molecular Panels for Diagnosis of Gastrointestinal Infection: Performance, Result Interpretation, and Cost‑Effectiveness. J Clin Microbiol 53. https://doi.org/10.1128/jcm.02103-15
2. Beal SG, Tremblay EE, Toffel S, Velez L, Rand KH. 2018. A Gastrointestinal PCR Panel Improves Clinical Management and Lowers Health Care Costs. J Clin Microbiol 56. https://doi.org/10.1128/jcm.01457-17
3. Shane AL et al. 2017. Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea. Clin Infect Dis.
4. CDC Yellow Book 2024. Travelers’ Diarrhea. https://www.cdc.gov/yellow-book/hcp/preparing-international-travelers/travelers-diarrhea.html
5. Moon RC et al. 2023. Relationship between Diagnostic Method and Pathogen Detection, Healthcare Resource Use, and Cost in U.S. Adult Outpatients Treated for Acute Infectious Gastroenteritis. J Clin Microbiol.
Comparison of Target Detection Rates of Multiplex Gastrointestinal PCR Panels: A Systematic Literature Review & Meta-Analysis
Multiplex gastrointestinal (GI) panels have transformed the detection of infectious gastroenteritis by enabling rapid identification of multiple pathogens from a single test. However, broader panels can introduce challenges, including detection of non-clinically relevant organisms, increased diagnostic uncertainty, and potential overtreatment.
Developed by Cepheid and presented at IDWeek 2025, this scientific poster explores how targeted multiplex GI panel design can improve diagnostic confidence while supporting antimicrobial stewardship. Discover how targeted multiplex GI panel design can improve diagnostic confidence, support antimicrobial stewardship, and optimize laboratory efficiency.
Resource details:
- Resource type: Resource (presented at IDWeek 2025)
- Topic: Multiplex gastrointestinal PCR testing / infectious gastroenteritis
- Focus: Targeted vs broad GI panels and diagnostic stewardship
- Page count: 2
- Read time: 3 mins
Detection and identification of DNA and RNA from multiple bacteria, parasites, and/or virus in approximately 74 minutes
Multiplex gastrointestinal (GI) testing plays a critical role in the rapid and accurate identification of pathogens responsible for infectious gastroenteritis. Traditional diagnostic methods can be time-consuming and may lack sensitivity, making it challenging to guide timely and appropriate clinical decisions.
This resource sheet from Cepheid outlines the clinical utility and performance of the Xpert® GI Panel, a targeted multiplex PCR solution designed to deliver actionable results in approximately 74 minutes. Discover how by enabling fast pathogen identification, the panel supports earlier intervention, improved patient management, and more efficient laboratory workflows.
Resource details:
- Resource type: Product reference sheet
- Technology: Multiplex real-time PCR
- Application: Detection of gastrointestinal pathogens
- Pages: 2
- Read time: 2 mins
CE-IVD Xpert Test Menu
Multiplex molecular diagnostics are transforming the way clinical laboratories detect and manage infectious diseases, enabling faster and more accurate identification of pathogens across a wide range of applications.
This resource from Cepheid provides a comprehensive look at the CE-IVD Xpert® portfolio, highlighting available assays across multiple disease areas. Designed to deliver actionable results with speed and accuracy, the GeneXpert® system supports streamlined workflows and rapid clinical decision-making when it matters most.
Resource details:
- Resource type: Product text menu
- Technology: Molecular diagnostics (real-time PCR)
- Application: Multi-disease diagnostic testing
- Pages: 2
- Read time: 3 mins
Diagnostic excellence in the use of GI pathogen panels
Wednesday, July 15 at 16:00 BST | 17:00 CEST | 11:00 EDT | 08:00 PDT
With the expanding range of gastrointestinal (GI) diagnostic options, selecting the right test has become increasingly complex. In this SelectScience® webinar, hosted in collaboration with Danaher company, Cepheid, explores how principles of diagnostic excellence and stewardship can guide optimal use of GI pathogen panels.
Through a combination of clinical and laboratory perspectives, speakers will discuss practical strategies for improving test selection, interpretation, and clinical impact. They will also highlight key challenges such as co-detection, distinguishing colonization from infection, and aligning testing approaches with clinical context.
Attendees will gain actionable insights to enhance diagnostic accuracy and support better patient care.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
- Cost: Free to attend
- Location: Online
- Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
A look inside Cepheid's Xpert GI Panel
This video introduces syndromic PCR testing for acute gastroenteritis, highlighting the benefits of multiplex molecular diagnostics for rapid pathogen identification.
Discover how the Xpert® GI Panel from Cepheid enables the simultaneous detection of 11 common causes of gastroenteritis in just over an hour, supporting faster clinical decision-making compared with traditional testing approaches. By focusing on the most relevant pathogens associated with acute gastroenteritis, the test helps clinicians deliver targeted care while supporting diagnostic stewardship practices.
