xMAP® Technology

Since biological assays are typically coupled to a colorimetric readout, the notion of ‘multiplexing’, or reading multiple test results in a single sample volume has been complicated primarily by spectral overlap. Color from one assay detection channel interferes with color in other detection channels. This limitation has made such multi-color assays useful only to a few analytes per sample. Download this application note to find a variety of methods and protocols for multiplex assays using xMAP® Technology.

The 4vHPV and 9vHPV vaccines provide additional protection against types of HPV responsible for other diseases, including genital warts along with vulvar, vaginal, and anal cancers. xMAP multiplexing technology, especially the cLIA and total IgG LIA assays, has facilitated the development and clinical testing of these vaccines in a high-throughput and robust manner. Download this white paper to find out the true power of xMAP technology.

In this white paper, Luminex outlines the applications and benefits of its xMAP technology for serological analysis. Multiplex serological testing can be particularly useful in a pandemic, as it can simultaneously analyze large numbers of antigens for large-scale screening and has the potential to replace traditional ELISA assays. Here, it is demonstrated that xMAP technology has become an established benchmark for running these multiplex serology tests.

This whitepaper explains how multiplex methods deep bisulfite sequencing and bisulfite PCR-Luminex can be used for DNA methylation analysis in research examining epigenetic modification.

Until recently, none of the commercially available multiplex molecular tests could provide the flexibility to satisfy clinicians' desire for both targeted and broad respiratory pathogen testing in a cost-effective manner for the lab and patient. The VERIEGENE® Respiratory Pathogens Flex Test (RP Flex) is the first commercial test that allows the user to choose any combination of 16 viral and bacterial targets for an individual sample at the time of test ordering, based on the clinician and patient’s needs. The purpose of this white paper is to deliver an overview of the advantages of using VERIEGENE® for your diagnostic needs.

Timely and accurate identification of suspected pathogens in stool specimens from gastroenteritis patients can be challenging due to the similar clinical signs and symptoms in many diarrheal diseases. In this white paper, Luminex describes the use of the xTAG® Gastrointestinal Pathogen Panel (GPP) to accurately identify pathogen species involved in diarrheal and gastrointestinal infections.

In this video, Luminex describes how it is working with Wageningen University to help the center explore the potential of nature to improve the quality of life.

Luminex Corporation was awarded with a SelectScience Digital Marketing Award for its social media parody video, Multiplex Star. Here, Hilary Graham, Ph.D., virtually accepts the award for Best Viral Branded Video.

In this video, discover DigiWest, a high-throughput immunoassay that can analyse up to 800 proteins. DigiWest combines xMAP® multiplexing technology from Luminex with classic Western Blot procedure for high-content protein profiling.

Luminex’s xMAP® Technology combines advanced fluidics, optics, and digital signal processing with proprietary microsphere technology to deliver multiplexed assay capabilities. Featuring a flexible, open-architecture design, xMAP Technology can be configured to perform a wide variety of protein or nucleic acid assays quickly, cost-effectively and accurately.

In this video, Professor Godfrey Grech, of the University of Malta, presents data on how multiplex bead-based RNA assays have enabled his team to identify key cancer-driving amplifications in triple negative breast cancer and develop novel therapeutic compounds.

Professor Evi Lianidou discusses how her team at the University of Athens is using multiplex bead-based assays to profile circulating tumor cells at the single-cell level, in an attempt to understand why some have a greater propensity to metastasize than others.

Associate Professor Jochen Schwenk discusses how bead-based affinity proteomics, using xMAP technology, is enabling researchers at the KTH Royal Institute of Technology, Stockholm, to map the entire human proteome.

Dr. Tim Waterboer, head of the Infection and Cancer Epidemiology research group at the German Cancer Research Center, specializes in understanding population trends in infectious disease and cancer. In this video, he provides an insight into some of his most recent findings using multiplex serology – including the realization that HPV accounts for a large proportion of head and neck squamous cell carcinoma cases in men.

Accurate discrimination of pneumococcal serotypes is critical to defining the most appropriate treatment regimen for patients and tracking population changes. In this video, Ger Rijkers, Professor in Biomedical and Life Sciences at University College Roosevelt, discusses how his team is focused on developing tools for easy and accurate identification of all serotypes, with multiplex antigen serology.

Discover how Thomas Joos and his team at Natural Medicines Institute (NMI) are utilizing the xMap Technology from Luminex and have become leaders in multiplex immunoassay development.

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Prof. Dr. Ger Rijkers tells SelectScience how he is using Luminex xMAP Technology® to develop a multiplex assay that can identify specific antibodies to multiple serotypes of S. pneumoniae in a single test

Customized multiplex xMAP assays enable the development of efficient, cost-effective diagnostic tests for cancer and infectious diseases