Products & ReviewLab Automation

Thermo Scientific Multidrop Combi nL

The Thermo Scientific Multidrop Combi nL – A low volume bulk reagent dispenser, expanding the range of the market-leading Multidrop product family. The Multidrop Combi nL provides accurate and consistent high throughput reagent dispensing across a volume range of 50nL to 50µL. It offers low volume dispensing into 96-, 384- and 1536- well plates with excellent precision and accuracy. Fast dispensing combined with full robotic…

Thermo Fisher Scientific

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Average Rating 4.5

|6Scientists have reviewed this product

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Very precise and easy to operate; highly reliable

 

Average Rating 5.0

Application Area:

High throughput screening in 1536well format

Highly efficient and very reliable reagent dispenser especially for high through put screen assays. Chances of clogged tips is relatively low. Pressure system instead of vacuum seems to work very well. I compared this with other vendors and in house built reagent dispensers. For cell dispensing, this system is highly reliable. Highly precise dispensing of reagents. Very easy to operate and consistent results. Having a lap top computer to operate the instrument may be a little inconvenient. However, the ease of operation and reliability compensates for it.

Review Date: 2 Feb 2017 | Thermo Fisher Scientific

Average Rating 4.0

Application Area:

Reagent Dispensing

This instrument works great for small volume (nL) dispensing of any pattern into microwell plates including 384 and 1536. Because of the small bore size of the valve necessary to dispense nL volumes you must rinse the lines thoroughly after each use or clogs will form. Nice price point, great accuracy and precision. I recommend this instrument.

Review Date: 26 Sept 2014 | Thermo Fisher Scientific

Average Rating 4.0

Application Area:

Liquid Dispensing

I have used the Multidrop Combi nL consistently during my years of lab work. It is very user-friendly and extremely precise and accurate. My application was mostly on various types of 384-well plates running fluorescence assays with multiple reagent additions to single plates. The Combi nL was quick and reliable. Any errors generated could be quickly resolved without intervention of an expert, which was very important to me as I was doing time-sensitive assays. It's flexibility in allowing additions to various rows and columns of the plate was invaluable. I always QC'd the Combi before any screen, and never found issues in the QC. If this piece of equipment is properly maintained (ie. cleaning protocol followed every time, and corrosive reagents avoided during use), it is an extremely solid piece of automation to have in the lab. I never used after-sales services, which is why I gave that portion of the review 3/5 stars.

Review Date: 20 Mar 2014 | Thermo Fisher Scientific

Average Rating 4.0

I find the Combi nL to be a very useful and easy to use instrument. However programming the methods could be a bit more intuitive.

Review Date: 15 Jun 2011 | Thermo Fisher Scientific

Average Rating 5.0

An excellent liquid handler.

Review Date: 3 Feb 2010 | Thermo Fisher Scientific

Average Rating 4.7

Review Date: 3 Feb 2010 | Thermo Fisher Scientific

The Thermo Scientific Multidrop Combi nL – A low volume bulk reagent dispenser, expanding the range of the market-leading Multidrop product family.

The Multidrop Combi nL provides accurate and consistent high throughput reagent dispensing across a volume range of 50nL to 50µL. It offers low volume dispensing into 96-, 384- and 1536- well plates with excellent precision and accuracy. Fast dispensing combined with full robotic compatibility ensures increased assay throughput for laboratories needing low volume assay formats.


Key Features:

  • Reliability—accurate dispensing over a 50nL to 50µL range, giving high quality assay data
  • Increased flexibility –select rows, columns, or individual wells with the intuitive FILLit Software
  • Easy-to-use—visual, icon-based onboard user interface makes all functions easy to set up, use, and maintain
  • Reduced reagent costs—reliable low volume dispensing, a minimal dead volume and backflush of expensive reagents

Application areas:

  • Primary and secondary screening
  • Drug Discovery
  • Assay development
  • Compound management
  • PCR reaction set-up
  • Sequencing

Application NoteLife Sciences

Optimization of a Bulk Reagent Liquid Handler for Low Volume Dispensing

This application note describes the performance of Thermo Scientific Multidrop Combi nL in low volume and the operating principle of the valves. Multidrop Combi nL provides consistent, high-throughput dispensing into 1536-, 384- and 96-well microplates covering a volume range 50 nl - 50 µl. In this application note liquids with different surface tension properties were tested by dispensing multiple volumes into 1536- and 384-well plates. Descriptions of the liquid calibration and the valve correction feature with the Thermo Scientific FILLit Software are also presented.

Master the art of pipetting with techniques and trends for optimal genomic sample handling

Join Steve Beckett, Senior Technical Sales Specialist for Liquid Handling Solutions at Thermo Fisher Scientific, as he presents strategies to improve pipetting and enhance productivity in genomic workflows. He will highlight various pipetting techniques, discuss challenges and solutions for genomic workflows, and reveal future trends in laboratory products and genomic workflows.

Key takeaways include:

  • Learn the correct pipetting techniques to improve ergonomics in genomic workflows
  • Understand pipetting for genomic sample preparation and storage processes
  • Discover future trends in pipetting and liquid handling within genomic workflows

Who should attend?

This webinar is ideal for anyone involved in pipetting within genomic workflows, including those using automated liquid handlers.

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.


Multidrop™ Combi nL Reagent Dispenser

This video presents the Multidrop™ Combi nL reagent dispenser for accurate and reliable low-volume dispensing in pharmaceutical and biotechnology laboratories. The Multidrop™ Combi nL is an easy to use bench top automated system that provides accurate reagent dispensing with a volume range of 50nL to 50µL.

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