Octet® R8 BLI System
Superior quantitation and kinetics performance with increased assay flexibility and cost efficiency.
Receive your quote directly from the manufacturer.
Great Equipment, takes minimum space!
Bio Molecular Interaction Analysis and Affinity Characterization
Hi, R8 is a great Equipment!, Its very precise and user friendly. This is our second product of the same make. As service providers, the value we generate for the customers is incredible. Most of our customers are very happy with service we provide, and we could not have done without Octet Red96/R8. It's worth investing for long term usage!
Review Date: 17 Apr 2025 | Sartorius Group
BLI makes kinetic characterization and quantitation easy!
Kinetics & quantitation
Octet R8 is a great equipment for any lab which would like to test their samples for binding, do kinetic characterization and sample quantitation. It is quite fast and informative (compared to techniques such as ELISA), but it is costlier.
Review Date: 13 May 2024 | Sartorius Group
Would buy that instrument again.
IgG Quantitation in Cell Line Development
Easy to use instrument, good results. Easy to explain to new users. Great support.
Review Date: 14 Jul 2022 | Sartorius Group
Superb instrument, ideal for high throughput work!
Protein-ligand and Protein-protein interaction, fragment based drug development
The equipment is very easy to operate and great user interface. Moreover, we have achieved great results in our experiments. In fact, we need a very less quantity of protein/ligand to quantitate. It is extremely fast and can perform high throughput experiments easily. Great for screening purposes.
Review Date: 2 Apr 2022 | Sartorius Group
First choice for interaction studies.
Drug discovery
Octet is very easy to use system for fast screening of protein - small molecule interaction studies. Easy to maintain and definitely value for the money because of time saved in measurements time.
Review Date: 20 Jan 2022 | Sartorius Group
Great results, can’t live without this instrument!
Drug discovery
State of the art technology
Review Date: 19 Jan 2022 | Sartorius Group
Great value
High throughput screen
This machine is user-friendly and easy to use, which can be used for HTS.
Review Date: 19 Jan 2022 | Sartorius Group
Great results
Analysis
Great results
Review Date: 19 Jan 2022 | Sartorius Group
Using BLI technology - Octet R series has no match
Drug discovery
Octet R series is fast, easy to use & software is very friendly. Results can be obtained in 3 - 4 hrs run time, even with low volume samples. I strongly recommend as it is very economical , compared to other players in market. Efficient sales & service team to serve customers. Prompt service by team Sartorius.
Review Date: 11 Jan 2022 | Sartorius Group
Powerhouse biomolecular equipment.
Protein ligand binding and antibody kinetics
A powerful addition to our lab. The striking feature that comes up time and again is that the sample is preserved so the ability to control experiments and analyse samples by other techniques is a huge advantage over injection-based flow systems. I can run multiple antibodies through the very same sample and be certain that the result is real and not just ruled out as an anomaly or error.
Review Date: 7 Dec 2021 | Sartorius Group
The 8-channel system - Octet® R8 - offers an advanced fluidics-free approach to protein characterization. The independent biosensors allow analysis of single or up to eight channels, enabling flexibility in sample throughput based on need. The Octet system performs quantitation of 96 samples in 32 minutes and kinetic screening of 64 samples in 1.5 hours.
The system utilizes Bio-Layer Interferometry (BLI) technology. The real-time technique enables direct detection of specific proteins and other biomolecules — even in complex mixtures like cell culture supernatants and lysates and low concentration environments.
Furthermore, the label-free technology gathers physiologically relevant data quickly, proving to be a cost-effective method.
Key Benefits:
- Large dynamic range for comfortable titer determination Versatile kinetic analysis from small molecules (150 Da) to cells
- Temperature Control (15–40°C) Evaporation protection for long off-rate measurements
- Full post-analysis sample recovery Low maintenance and operational costs
- Ready for GxP regulated environments
Popular industrial applications include expression screening, on- and off-rate screening, epitope binning, cell line development and bioprocess optimization.
The Octet® R8 system is widely used in analytical core labs for protein structure/function studies and small molecule screening campaigns. The system has been developed to operate reliably in a regulated environment. Sartorius offers 21 CFR Part 11 software and a full line of GxP products and services as part of the Octet® R8 GxP Package.
Brochures
Octet System Qualification Products and Services
This product brochure provides an overview of the qualification products and services that can help you meet your initial and ongoing system qualification requirements.
Octet Assay Systems: Dip and Read Assays
The Octet family of instruments is designed to meet a broad range of application and workflow requirements, including antibody characterization, a variety of protein interactions and vaccine research. The following brochure outlines the instruments in the Octet Assay family to ensure selection of the best instrument for your application.
Octet Assay Systems Brochure
This brochure outlines the Octet family of instruments and describes the wide range of applications they can be used for, including; interaction analysis, antibody characterization, vaccine research, lead optimization and pharmacokinetics. It also includes a simple guide to help you chose the right system and biosensor for your application.
Enhanced BLI analytics with new heights of sensitivity
Explore Sartorius’ most advanced biolayer interferometry (BLI) solution, designed for high-throughput, real-time biomolecular interaction analysis. The Octet® R8e delivers best-in-class sensitivity, enabling accurate detection of low molecular weight and low-abundance analytes. With features like 384-well plate compatibility, reduced sample volume (as low as 40 µL), extended unattended runtime (up to 16 hours), and intuitive software for streamlined workflows, this system empowers researchers to achieve reliable results faster and more efficiently. Ideal for applications across drug discovery, biologics development, and manufacturing.
Octet® AAVX biosensors for quantitation of AAV capsids
Adeno-associated virus (AAV), with low immunogenicity and toxicity, has become one of the most promising viral vectors in the field of gene therapy. A rapid and robust method for AAV capsid quantitation is essential for AAV bioprocess development and manufacturing. This tech note introduces a rapid, label-free method for direct capture and quantitation of various AAV serotypes on the Octet® Bio-Layer Interferometry (BLI) Platform using the Octet® AAVX Biosensors.
Cell line development: Accelerating process optimization by combining Ambr 15 Cell Culture with Octet titer measurements
In this application note, Sartorius demonstrates the power of using the Ambr® 15 Cell Culture system with an integrated Vi-CELL XR and Ambr® Analysis Module together with an Octet® to identify optimum yield conditions in media screening and process optimization experiments.
Small molecule binding kinetics
This application note describes the method setup process for a successful protein-small molecule binding interactions analysis on Octet® R2, R4, R8, RH16, and RH96 instruments. Discover tips on best practices for the preparation of optimal reagents for small molecule binding studies and data analysis including data referencing procedures.
A fast and high-precision influenza vaccine potency assay
This application note presents a vaccine potency assay performed using Octet systems, in which samples are analyzed in their natural state without the use of detergents. Octet systems are capable of analyzing whole virus, split virions and recombinant HA vaccine samples.
Intelligent tools to generate clonal cell lines faster
The generation of biologic-producing cell lines comprises numerous time-consuming, expensive, and often technically challenging steps.
In this new eBook, we examine these challenges in greater detail and explore a range of intelligent analytical solutions that can be incorporated into cell line development workflows to eliminate bottlenecks in clone selection, fast-track development timelines, optimize CQAs, and reduce costs.
Download your free copy today to learn more about:
- Critical steps in cell line development
- Areas to improve efficiency
- Overcoming bottlenecks through streamlined clone selection
- Accelerating process optimization with integrated analysis tools
Top ten reasons to choose Sartorius Octet BLI technology to accelerate your research, development, and manufacturing
Octet® systems enable analytical assessment of biologics in various stages of the development workflow. In this infographic, Sartorius describes how Octet® bio-layer interferometry (BLI) technology can accelerate your research, development, and manufacturing.
Octet Systems: Superior performance, unrivaled flexibility
Your research should be guided by your imagination, not by the limitations of your label-free system. In this brochure, Sartorius introduces the Octet® platform's, with flexible, open-format design and comprehensive menu of biosensors letting you attack research challenges in unique new ways.
Best practices for protein characterization excellence
Recent advancements in the field of biologics, whether in terms of research, development or production, have been greatly attributed to real-time label-free (RT-LF) technologies. This biosensor-based technology is especially crucial for the characterization of molecular interactions across various stages in biopharmaceutical discovery, development and production.
Download this eBook to explore the best practices and protocols to generate high-quality data quickly and easily using the Octet® BLI platform – designed to offer a comprehensive solution for your protein characterization needs. From vaccine potency to quantitative screening of bispecific antibodies, you'll find a range of applications designed to help you:
- Avoid later-stage failures
- Rapidly screen large antibody libraries
- Evaluate diverse assay conditions
- Fast-track development
Bio-layer interferometry (BLI) technology
In this infographic, Sartorius presents a label-free alternative for characterizing protein-protein and drug-protein interactions in standard microtiter plate format and helps you choose an Octet® system tailored to your particular requirements.
Accelerate assay development and reduce cycle times for AAV quantification in complex biological samples
Assessing AAV vector quality in gene therapy manufacturing is crucial, but the current gold standard, serotype-specific ELISA, has its drawbacks — time-consuming and prone to matrix effects. In this webinar, Dr. Yoann Saucereau from ExcellGene reveals how a label-free approach not only cut down on complexities in biological matrices but also enabled a quick, routine method. Now, ExcellGene effortlessly analyzes up to 96 samples in under 30 minutes for efficient AAV platform development.
Key learning objectives
- Explore how suitable QC workflows are established in AAV development and manufacturing
- Discover the critical role of assay design and development to determine correct binding kinetics, affinity values or analyte concentrations
- Consider the optimization and evaluation of an AAV titer assay in comparison to Octet® AAVX Biosensors
Who should attend?
- Lab researchers
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
Octet BLI solutions - Part 4 - High-throughput applications
Watch this video to find out about the high-throughput applications of Sartorius' Octet Systems.
Strategies for simplifying viral vaccine and biotherapeutic discovery
Watch this presentation by Allan Schell, David Apiyo, and Victoria Yatsula, titled: Strategies for simplifying viral vaccine and biotherapeutic discovery. This talk was presented at the SelectScience® Virtual Microbiology and Infectious Disease Summit 2022.
Octet BLI solutions: Part 2 – Instruments
The Sartorius Octet® bio-layer interferometry (BLI) system allows researchers to analysis protein-protein and protein-small molecule interactions. In this video, Sartorius introduces the Octet® R series that provides a modular and scalable solution for molecular screening in 96-well microplates.
Octet BLI solutions: Part 3 – Applications
In this video, Sartorius demonstrates the range of applications bio-layer interferometry (BLI) has in biomolecular analysis workflows and the drug discovery pipeline, including the benefits of the Octet® BLI systems across the entire workflow.
Octet BLI solution: Part 1 – Technology
In this video, Sartorius presents the evolution of the Octet® bio-layer interferometry (BLI) system, providing researchers with a label-free approach to monitoring biomolecular interactions, for over 15 years.
Rapid and real-time results for the study of viral biology and development of antiviral therapies
Dr. Rebecca Dubois, Associate Professor in the Department of Biomolecular Engineering at the University of California, Santa Cruz, outlines the advantages of using Sartorius' Octet® platform in her research to understand the molecular mechanisms of human viral infection and to develop new vaccines and antiviral therapies.
Octet® Systems for Biologics Characterization
Learn why so many choose ForteBio Octet® Systems in these customer testimonials.
Revolutionize care with pioneering bispecific antibody therapy
Jiseon Kim, Senior Scientist at ProGen, explores the transformative potential of a bispecific antibody-based drug to lay the foundation for improved healthcare quality
A look at 6 top-rated biopharmaceutical products
Find out what scientists are saying about the biopharmaceutical lab products they use
Biopharmaceuticals: Oligonucleotide analysis, regulatory compliance, and more
Explore the latest research, expert insights, and new technology driving biopharmaceutical discovery and development
Harnessing the power of label-free molecular interaction analysis in biopharmaceutical characterization
Dr. Kalhari Silva, the Head of Scientific Innovation and Research at Custom Biologics, shares how her organization is able to offer a complete package of bioanalytical testing services that are compliant with evolving regulatory requirements
Meet the winners of the 2022 Scientists’ Choice Awards for Drug Discovery & Development
Scientific, technological, and communications excellence has been celebrated at SLAS2022 with MOBILion Systems, Agilent Technologies, and Wyatt Technology Corp. among those recognized
8 upcoming webinars to boost your research capacity
Discover insights on topics from lab automation and gene therapy to monoclonal antibodies and clinical diagnostics
5 upcoming webinars to support your research
Discover insights on topics from cell line development and cancer research, to preparative HPLC and COVID-19 testing
New eBook details best practices for protein characterization excellence
Download our new eBook presenting optimal label-free approaches to generate high-quality data fast
Therapeutic antibodies: Advancing the development of COVID-19 neutralizing antibodies
We hear from Kevin Entzminger on how Abwiz Bio is developing next-gen antibody therapeutics to help answer fundamental questions in science
Secrets to label-free protein analysis in a shared resource lab
Join us Tuesday, July 6, to discover how to optimize your biomolecular interaction analyses for higher throughput and efficiency
