NovoCyte Advanteon Flow Cytometer
Performance you can trust with the flexibility you need.
Receive your quote directly from the manufacturer.
Great piece of equipment and fantastic after care team!
Analyse Sperm Acrosome Reaction
Easy to use and the maintenance is easy to follow. The data provided is great and you can change and update protocols to suit your assay requirements with ease. The customer service and after-sales teams are brilliant and will answer any queries with a great response time.
Review Date: 10 May 2024 | Agilent Technologies
Easy to use.
Flow cytometry
The instrument is easy to use and with good daily QC sample.
Review Date: 16 Nov 2021 | Agilent Technologies
The NovoCyte Advanteon flow cytometer builds upon the highly successful NovoCyte, and NovoCyte Quanteon. The system provides an advanced set of capabilities for the most demanding scientists, yet is remarkably simple to operate. The NovoCyte Advanteon can accommodate high-end and increasingly sophisticated multicolor flow cytometry assays. The system offers flexibility with 1, 2, or 3 laser options, up to 21 fluorescence channels, and 23 independent detectors.
The NovoCyte Advanteon is customizable to meet your specific needs but is easily upgradeable to meet your future demands. When throughput is essential, the NovoSampler Q can be integrated into different laboratory automation platforms. The sampler can efficiently process both FACS tubes (using a 40-tube rack) and 24-, 48-, 96-, and 384-well plates. For the NovoCyte Advanteon, the intuitive and industry-honored NovoExpress software is now even more advanced, providing an exceptional user experience in data acquisition, analysis, and reporting.
Brochures
Agilent NovoCyte Advanteon flow cytometer brochure
The Agilent NovoCyte Advanteon flow cytometer builds upon the highly successful Agilent NovoCyte and NovoCyte Quanteon to provide an advanced set of capabilities for the most demanding scientists, yet is remarkably simple to operate. Download this brochure to find out more.
Rewiring the metabolism of CAR-T cells
Join Professor Mercedes Rincon, University of Colorado Anschutz School of Medicine, as she discusses the groundbreaking advancements in adoptive T cell therapy, particularly chimeric antigen receptor (CAR) T cell therapy. While CAR-T therapy has achieved impressive complete remission rates in 60–90% of patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r-B-ALL), challenges such as treatment failures and relapses remain significant obstacles.
Metabolism plays a critical role in T cell function, shaping immune responses. While glycolysis is essential for T cell expansion, it can restrict the self-renewal capacity of CAR-T cells during manufacturing. Mitochondrial respiration is vital for their survival and effectiveness. Recent findings have highlighted MCJ, a protein that negatively regulates mitochondrial function in CD8 cells. Loss of MCJ enhances mitochondrial respiration, cytokine secretion, and anti-tumor activity. Targeting MCJ to boost mitochondrial metabolism presents a promising strategy to enhance the efficacy of CAR-T cells and advance adoptive T cell therapies.
Key learning objectives
- Understand the current landscape of adoptive T-cell therapy
- Explain the role of metabolism in T cell function, highlighting the significance of glycolysis and mitochondrial respiration in enhancing CAR-T cell efficacy
- Identify the potential of MCJ as a therapeutic target to improve mitochondrial metabolism, cytokine secretion, and overall effectiveness of CAR-T cell therapies
Who should attend?
- Researchers and scientists specializing in CAR T-cell therapy, immunotherapy development, cell metabolism, glycolysis, and mitochondrial respiration.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
4 upcoming webinars to help reach your research goals
Discover the latest tools and techniques to expand your research capacity with expert-led presentations on chromatography, drug discovery, biosafety, and more
Agilent expands line of flow cytometers with the NovoCyte Penteon
The new line aims to provide unmatched sensitivity, resolution, speed, and flexibility of colors
