MILLIPLEX® MAP 11-Plex Akt/mTOR Panel – Phosphoprotein
The MILLIPLEX® MAP 11-Plex Akt/mTOR Panel – Phosphoprotein is used for the simultaneous quantification of the following Human, Mouse, Rat analytes: Akt (Ser473), GSK3α (Ser21), GSK3β (Ser9), IGF-1R, IR (Tyr1162/Tyr1163), IRS1 (Ser312), mTOR (Ser2448), p70S6K (Thr412), PTEN (Ser380), RPS6 (Ser235/Ser236), TSC2 (Ser939)
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The MILLIPLEX® MAP 11-Plex Akt/mTOR Panel – Phosphoprotein is used for the simultaneous quantification of the following Human, Mouse, Rat analytes: Akt (Ser473), GSK3α (Ser21), GSK3β (Ser9), IGF-1R, IR (Tyr1162/Tyr1163), IRS1 (Ser312), mTOR (Ser2448), p70S6K (Thr412), PTEN (Ser380), RPS6 (Ser235/Ser236), TSC2 (Ser939)
Analysis of Akt/mTOR Signalling in Cancer Cell Lines
In this application note Dr Joseph Hwang, from EMD Millipore’s Cell Signaling Group, demonstrates the utility of a bead-based multiplex assay that allows for the simultaneous detection of multiple phosphorylated Akt/mTOR pathway proteins. As nearly all of the players in the Akt/mTOR signalling pathway are co-ordinately regulated by phosphorylation, understanding the role of this pathway in normal physiological processes and in diseases such as cancer and diabetes requires the ability to simultaneously measure phosphorylation status of multiple protein targets.
