Leprechaun
The unmatched lentivirus and exosome characterization tool
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Find your pot of gold.
Leprechaun is the only system that hunts down titer and structure for viruses and exosomes without worrying about sample purity. Triple-check lentivirus particles to be sure they are the right size, have the right structure and contain RNA – in both crude and pure samples. Uncover exosome concentration and phenotype in everything from cell culture to biofluids. Make your own luck and follow Leprechaun straight to the viral titer or exosome concentration you’ve been looking for, without the noise from trickster particles throwing you off the trail.
Master EV profiling with Leprechaun – A case study from North Texas Eye Research Institute
Thursday, September 17 at 16:00 BST | 17:00 CEST | 11:00 EDT | 08:00 PDT
Extracellular vesicle (EV) profiling is critical to the understanding and diagnosis of many diseases. While essential, it is limited by traditional methods that require EV isolation, provide only one piece of the characterization puzzle, or process samples one at a time. Leprechaun is the ultimate tool for EV characterization that provides EV size, titer, and surface marker or cargo profiling from a single assay with maximum 25 µL of sample. It can work with samples direct from crude, such as biofluid or cell culture media.
Join this SelectScience® webinar for an overview of Leprechaun and see how North Texas Eye Research Institute (NTERI) uses it to profile EVs directly from tears, saliva and cultured cells. Learn how Leprechaun is critical to NTERIs mission of discovering, developing, and delivering novel therapies for the treatment of corneal trauma and diseases.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
Cost: Free to attend
Location: Online
Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
Preventing the danger of unwanted CAR expression during lentivirus production
Join this exclusive webinar to discover advanced strategies for enhancing the quality of lentiviral (LV) vectors in cell therapy manufacturing.
Quality defects in LV vectors can significantly affect the efficacy and safety of final cell therapies. Despite their critical importance, there has been minimal focus on controlling and monitoring the quality of LV vectors used in cell therapy manufacture. Of particular concern is the risk of ‘breakthrough expression’ of the transgene, leading to CAR expression in producer cells and on the surface of the LV particle.
In this webinar, Lentitek will demonstrate how its promoter system is designed to significantly reduce breakthrough expression of the transgene in producer cells, maximizing the functional LV titer during anti-CD19 CAR vector production. Additionally, the webinar will showcase the Leprechaun platform from Unchained Labs, which promises precise identification and monitoring of CAR expression on the LV surface. This webinar is essential for professionals dedicated to improving quality and safety of cell therapies.
Key takeaways include:
- Preventing breakthrough expression: Comprehend why preventing breakthrough transgene expression is critical for the safety and efficacy of your cell therapy.
- Optimizing LV performance: Understand how Lentitek’s system can help prevent unwanted transgene expression.
- Comprehensive quality monitoring: Learn how Leprechaun helps you monitor breakthrough expression by measuring the titer of LV with transgene protein on the surface straight from harvest.
Who should attend?
- Senior scientists, professors, and postdoctoral researchers working in lentiviral process and analytical development.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
