FO-SPR Carboxyl probes
Dip-in probes with a generic surface chemistry that can couple a wide range of biomolecules
Carboxyl fiber-optic SPR-based probes
Carboxyl fiber-optic SPR-based probes
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Our customizable, interchangeable probes consist of a gold-coated, optical fiber with a standard carboxyl surface chemistry that allows the binding of a range of proteins and biologics. These disposable probes are placed in the White FOx, a high-end, semi-automated analytical benchtop instrument for real-time analysis of biomolecular interactions.
This sensor technology uses the fiber-optic surface plasmon resonance (FO–SPR) principle for both labelled and label-free detection of biomolecules, including proteins, antibodies, nanobodies, complex particles, microvesicles or cells in microliter volumes.
Within a few minutes, you can get accurate information on binding affinity, kinetics or target concentration.
These interchangeable probes mean that the White FOx can detect different target molecules with a single device, giving you full flexibility in use.
Benefits:
- Easy-to-use dip-in probe
- Performance and speed of surface plasmon resonance
- Standard carboxyl surface chemistry can bind a range of proteins and biologics
- Disposable and interchangeable for easy protocol switching
Applications:
- Label-free quantification of protein and antibodies
- Fast sandwich assays
- Kinetics
- Crude matrices/blood
- Large particles and vesicles
Sensitive protein quantification in crude serum samples: Comparison of FO-SPR and ELISA
This application note demonstrates the potential of FOx BIOSYSTEMS’ fiber-optic surface plasmon resonance technology (FO-SPR) for determining the concentration of a protein or antibody in crude samples, like serum. As an example, FOx demonstrate the detection of the therapeutic monoclonal antibody, infliximab (IFX), in patient serum samples. FO-SPR is a powerful tool that harnesses the power of SPR in an easy-to-use fiber-optic sensor.
Breaking limits in bioanalysis
In this video, meet the White FOx 1.0 from Fox Biosystems, a FO-SPR instrument designed to generate high-quality, cost-effective biomolecular data, fast, and over a wide range of applications.
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