CellASIC® ONIX Microfluidic System
The CellASIC® ONIX Microfluidic Platform delivers precise control for live cell analysis experiments by facilitating long-term perfusion cell culture. Cutting-edge microfluidics technology provides an improved cell culture microenvironment, exceptional quality for high magnification microscopy, and superior media switching capabilities.
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Great results. Very fast and easy to use. I expect to use it more going forward.
Proteomic and metalonomics. Metals and volatile samples.
I have been able to obtain precise results faster than when using other platforms.
Review Date: 4 Mar 2020 | Merck
The CellASIC® ONIX Microfluidic Platform delivers precise control for live cell analysis experiments by facilitating long-term perfusion cell culture. Cutting-edge microfluidics technology provides an improved cell culture microenvironment, exceptional quality for high magnification microscopy, and superior media switching capabilities.
Measure cell responses to pre-programmed perfusion, temperature, and gas environment changes. The CellASIC® Microfluidic Platform automates all the requirements for long term control of the cell culture environment, giving you the control you need to discover new science.
Features:
- Preprogrammed changes to gas, temperature and flow for hands-free operation.
- Software-driven flow switching with customizable flow rates.
- Glass bottom plates are optimized for inverted microscope visualization.
CellASIC® ONIX Live Cell Analysis Platform for Neural Stem Cell Microenvironment Control
Neural stem cells (NSCs) are sensitive to microenvironmental cues, including cell-cell contact, cell-ECM interaction, nutrient and waste transport, as well as environmental oxygen composition. However, how these parameters in the microenvironment affect the stem cells’ morphology, proliferation, and differentiation remains an open area for research. This application note demonstrates how the CellASIC® ONIX Microfluidic Platform with its microfluidic cell culture devices are capable of multi-parametric microenvironment control for NSC studies.
Demonstration of Long-Term Culture and In-Plate Staining Protocols Using the CellASIC® ONIX Microfluidic Platform
The ability to analyze cell responses to perturbations over time greatly extends the precision and biological relevance of in vitro studies. This application note demonstrates the long-term culture of multiple cell lines using automated perfusion protocols set up with intuitive CellASIC® ONIX FG Software, comparing the results to those obtained using traditional chambered slides. The results indicate that optimal experimental parameters can vary greatly with respect to the particular cells being cultured.
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