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Organoids

Merck's offering includes exclusive access to patient-derived organoid biobanks utilizing HUB Organoids for licensing ease as well as access to organoid screening and assay development services.

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Organoids are complex collections of cells grown in a 3D culturing medium that recapitulate many of the physiological and genomic features of various tissues or organs. Organoids are derived either from embryonic stem cells (ESC), induced pluripotent stems cells (iPSCs) or adult stem cells (ASCs) and differentiate through a series of controllable signaling cues into a diverse set of cell types resembling those found in their respective physiological tissues.

Once culturing and differentiation conditions are established for a particular organoid type, they can be reproducibly created by researchers employing basic cell culturing methodologies. In the previous decade there has been an explosion of exciting advancements in this field including the generation and characterization of new organoid types, as well as applications for these organoids to advance basic biological research and in the development of novel therapeutics.

Merck's offering includes exclusive access to patient-derived organoid biobanks utilizing HUB Organoids for licensing ease as well as access to organoid screening and assay development services.

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