ACQUITY UPLC M-Class System with HDX Technology
The ACQUITY UPLC® M-Class System with HDX Technology leverages UPLC® separations and high-resolution MS to answer important questions about changes in protein conformation including: Drug candidate binding to a protein Biopharmaceutical product development Protein-protein interactions Intellectual Property The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and most o…
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The ACQUITY UPLC® M-Class System with HDX Technology leverages UPLC® separations and high-resolution MS to answer important questions about changes in protein conformation including:
- Drug candidate binding to a protein
- Biopharmaceutical product development
- Protein-protein interactions
- Intellectual Property
The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and most of all, easily, perform protein conformation studies. The system and its DynamX™ HDX Analysis Software removes the barriers to adopting high resolution LC and MS for routine studies of protein conformational changes, making hydrogen deuterium exchange with MS (HDX, HDX MS, HXMS, or H/D exchange) a core competency for your laboratory.
Why Choose the Acquity UPLC Plus Series: An Infographic
Since its introduction in 2004, each addition to the Acquity family has continuously pushed forward to enable you to find faster, simpler and better ways to support the work that you do.
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This white paper reviews various experimental parameters that influence the chromatographic performance of a trap-and-elute nanoLC method. The most important step in the method development process is to select an appropriate column and trap pair that maximizes chromatographic resolution so that the method is capable of thoroughly identifying proteolytic peptides.
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