1260 Infinity II Bio-SEC System
The 1260 Infinity II Bio-SEC System is a size exclusion chromatography (SEC) system designed to meet the challenges of analyzing biological polymers.
1260 Infinity II Bio-SEC and reliable operation
Flexible light scattering detectors in 1260 Infinity II Bio-
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The 1260 Infinity II Bio-SEC System is a size exclusion chromatography (SEC) system designed to meet the challenges of analyzing biological polymers. The metal-free flow path ensures robust and reliable operation for harsh analytical conditions at high salt concentrations and extreme pH values. The 1260 Infinity II GPC/SEC Column Thermostat with optional cooling ensures sample integrity. And advanced detection methods, like multi-angle light scattering with SEC MALS detection, allow for the measurement of absolute molecular weight, size, and conformation of macromolecules in solution.
This unique combination makes the system the perfect solution for protein molar mass, purity, and aggregation analysis with advanced detection.
Features:
- Metal-free sample flow path allows robust characterization of biological polymers
- High salt tolerance and wide pH range with active seal wash and quaternary mobile phase blending offer increased flexibility
- Dedicated SEC column thermostat provides high capacity and cooling capabilities
- Flexible addition of multi-angle light scattering (MALS) detection enables the characterization of aggregation, size, and shape of biological polymers
- Compliant software support by WinGPC Software provides a dedicated SEC software platform
- Adding multidetector or dynamic light scattering detection provides more insights
- Your choice for performance and sustainability: The 1260 Infinity II LC System has received the My Green Lab ACT (Accountability, Consistency, Transparency) label after an independent audit to verify its environmental impact throughout the product life cycle.
Part 2: Size exclusion chromatography with light scattering for biopharmaceuticals
September 29, 2025, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT
Biopharmaceuticals based on monoclonal antibodies, lipid nanoparticle-encapsulated mRNA, and transgene-carrying viral vectors, are significantly larger than traditional small-molecule drugs. This size difference requires specialized analytical tools. Size-exclusion chromatography (SEC) is particularly effective for studying proteins and has recently been adapted to analyze complex macromolecular assemblies like mRNA and DNA.
Join us for this exciting two-part webinar series where Dr. Jelle De Vos from RIC group and Dr. Sonja Schneider from Agilent Technologies will discuss how SEC is evolving to meet the demands of modern biopharma. In Part 2, our experts will share real-world application examples of SEC with light scattering detection, highlighting how this powerful combination is transforming the analysis of complex biopharmaceuticals.
Key learning objectives of Part 2:
- Understand the practical application of SEC for the characterization of:
- monoclonal antibodies
- mRNA-lipid nanoparticle formulations
- adeno-associated viruses (AAVs)
- virus-like particles (VLPs)
Who should attend?
- Scientists and researchers in biotherapeutics R&D using SEC/light scattering.
- Lab and quality leaders, including lab managers, directors, and QA/QC professionals in biopharma production.
Want to go back and watch Part 1?
Click here to register for Part 1, and hear the fundamentals of SEC and discover how coupling it with light scattering detection can advance the characterization and development of biopharmaceuticals.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Part 1: Size exclusion chromatography with light scattering for biopharmaceuticals
September 15, 2025, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT
Biopharmaceuticals based on monoclonal antibodies, lipid nanoparticle-encapsulated mRNA, and transgene-carrying viral vectors, are significantly larger than traditional small-molecule drugs. This size difference requires specialized analytical tools. Size-exclusion chromatography (SEC) is particularly effective for studying proteins and has recently been adapted to analyze complex macromolecular assemblies like mRNA and DNA.
Join us for this exciting two-part webinar series where Dr. Jelle De Vos from RIC group and Dr. Sonja Schneider from Agilent Technologies will discuss how SEC is evolving to meet the demands of modern biopharma. In Part 1, our experts will cover the fundamentals of SEC and demonstrate how combining it with light scattering detection can enhance the characterization and development of biopharmaceuticals.
Key learning objectives of Part 1:
- Fundamentals of SEC: Understand the underlying theory and principles, along with the instrumentation used.
- Key aspects of SEC: Learn about particle size, pore size, column length, and factors affecting solute retention.
- Advanced techniques: Discover how multidetector setups incorporating light scattering can determine absolute molecular weight independent of column retention volumes.
Who should attend?
- Scientists and researchers in biotherapeutics R&D using SEC/light scattering.
- Lab and quality leaders, including lab managers, directors, and QA/QC professionals in biopharma production.
Interested to watch Part 2?
Click here to register for Part 2, and hear real-world stories how using SEC with light scattering detection can accelerate therapeutic development.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
