Part 2: Size exclusion chromatography with light scattering for biopharmaceuticals

September 29, 2025, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Biopharmaceuticals based on monoclonal antibodies, lipid nanoparticle-encapsulated mRNA, and transgene-carrying viral vectors, are significantly larger than traditional small-molecule drugs. This size difference requires specialized analytical tools. Size-exclusion chromatography (SEC) is particularly effective for studying proteins and has recently been adapted to analyze complex macromolecular assemblies like mRNA and DNA.

Join us for this exciting two-part webinar series where Dr. Jelle De Vos from RIC group and Dr. Sonja Schneider from Agilent Technologies will discuss how SEC is evolving to meet the demands of modern biopharma. In Part 2, our experts will share real-world application examples of SEC with light scattering detection, highlighting how this powerful combination is transforming the analysis of complex biopharmaceuticals.

Want to go back and watch Part 1?

Click here to register for Part 1, and hear the fundamentals of SEC and discover how coupling it with light scattering detection can advance the characterization and development of biopharmaceuticals.

Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes. If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.

Webinar details

  • Cost: Free to attend
  • Location: Online
  • Duration: 60 minutes

Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.

Speakers

Dr. Jelle De Vos
Dr. Jelle De Vos
Speaker
Senior Scientist, RIC group
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Dr. Sonja Schneider
Dr. Sonja Schneider
Speaker
Scientist, Application Development, Agilent Technologies
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Matilde Marques
Matilde Marques
Moderator
Assistant Editor, SelectScience

Who should attend?

  • Scientists and researchers in biotherapeutics R&D using SEC/light scattering.
  • Lab and quality leaders, including lab managers, directors, and QA/QC professionals in biopharma production.

What will this webinar cover?

Key learning objectives of Part 2:

  • Understand the practical application of SEC for the characterization of:
    • monoclonal antibodies
    • mRNA-lipid nanoparticle formulations
    • adeno-associated viruses (AAVs)
    • virus-like particles (VLPs)

Join the webinar to get answers to these questions:

  • How is SEC practically applied to characterize monoclonal antibody size, purity, and aggregation?
  • How can SEC/light scattering be used to analyze mRNA–lipid nanoparticle formulations?
  • What SEC strategies enable detailed characterization of adeno-associated virus (AAV) vectors?
  • How does SEC with light scattering support analysis of virus-like particles (VLPs)?
  • How is SEC evolving to meet analytical challenges in modern complex biopharmaceutical development?

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