The 10 Most Popular Application Notes this Month – and How They Could Help You!

22 Sept 2014
Kathryn Rix
Administrator / Office Personnel

Editorial article



1. LC-MS/MS Screening of 64 New Psychoactive Substances Using Dried Blood Spots

Learn about a robust, fast, sensitive and specific LC-MS/MS screening method for the determination of 64 new psychoactive substances in dried blood spots using a QTRAP® 5500 LC/MS/MS System.

2. A Novel Platform for Automated Production and Screening of Scaffold-Free Organotypic Microtissues

Discover a novel high-throughput top-loadable 96-well hanging drop culture system to enable automated mass production of primary and tumor microtissues.

3. Epigeneous™ H3K27Me3 Cellular Assay for Measuring Epigenetic Methylation

Your HTRF assays can be easily implemented on the Fluent laboratory automation solution to offer an efficient and robust high throughput screening solution.

4. QC Explained 1.0 - Quality Control for Point of Care Testing

This white paper from Randox describes the fundamentals of developing a POCT QC strategy and provides different types of POC devices and tips for choosing your IQC material and EQA scheme.

5. The Analysis of Common Drugs of Abuse in an Oral Fluid Matrix using a New QTRAP® Platform

Discover a simple and robust method for the detection of 16 drugs in an oral fluid matrix, using the AB SCIEX QTRAP® 4500 LC/MS/MS System.

6. Cell Cultivation without Contamination

In this white paper, learn about the BINDER CO2 incubator to help you reduce contamination and simplify sterilization.

7. LC-MS for In Vitro Diagnostic Use

Learn how to save time in the lab with a newly designed prototype two-channel HPLC and Tandem MS, coupled with data analysis, using Thermo Scientific™ ClinQuan MD™ prototype software.

8. Fluorescent Metastatic Mouse Imaging

Easily visualize and track your metastatic processes with the iBox® Explorer2 imaging microscope to reveal patterns of metastasis formation by human pancreatic carcinoma cells in mice.

9. Mass Spectrometry Buying Guide

This Buying Guide provides you with the information you require to help you make the right decision when choosing new mass spectrometry equipment.

10. Real-Time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers

The PHERAstar FS reader enables accurate roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.

Links

Tags

LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.IncubatorsLaboratory incubators are used to provide a stable environment to cultivate and store samples in, giving you optimal control of temperature, humidity, oxygen and CO<sub>2</sub> levels. Incubators are necessary equipment for cell culture and microbial research. Control temperature with heated or refrigerated incubators, or the levels of CO<sub>2</sub> and oxygen with CO<sub>2</sub> incubators. Using environmental chambers, create a humid climate for testing samples. Find the best incubators in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.